Author(s)

Yuanwei Wang^1*, Xiaodong Chen¹, Xiaomei Li², Baolin Zhu¹, Daoming Tong¹

¹Department of Neurology, the People’s Hospital of Shuyang, Shuyang, China.
²Centers for Disease Control and Prevention of Binzhou City, Binzhou, China.

We report isoniazid (INH) induced tics in one male patient on hemodialysis at end-stage renal failure. He had pulmonary tuberculosis, accepted isoniazid, rifampin, ethambutol, pyrazinamide and rifampicin. He developed tics on both sides of the face. Surprisingly, he was also found the bilateral symmetrical frontal lobe and dentate nucleus hyperintensities on T2-weighted and T2 FLAIR MR imaging. After excluding other causes, INH induced neurological side effect was suspected so the drug was stopped, pyridoxine was added and hemoperfusion was applicated. Tics disappeared after 1 week.

Tic, Isoniazid, Tuberculosis, ESRD, Hemodialysis

Wang, Y. , Chen, X. , Li, X. , Zhu, B. and Tong, D. (2017) Isoniazid-Induced Facial Tics in a Patient on Hemodialysis. Neuroscience and Medicine, 8, 25-28. doi: 10.4236/nm.2017.83003.