In this study, the potential effects of palm kernel oil (PKO), pineapple peels derived-activated carbon (PPAC) and NPK fertilizer (20:10:10) as amendment agents on the natural bioattenuation of 2,6-dichlorophenol (2,6-DCP) in tropical agricultural soil were investigated. The effect of PPAC dosage on 2,6-DCP biodegradation was also studied. Column reactors containing soil were spiked with 2,6-dichlorophenol (2,6-DCP) wastewater (300 mg/l) and amended with PKO, NPK fertilizer and PPAC alone or in combinations. The rates of 2,6-DCP biodegradation were studied for a remediation period of 42 days under laboratory conditions. The results showed that there was a positive relationship between the rate of 2,6-DCP biodegradation, bacterial growth rate and presence of NPK fertilizer and PPAC (alone or in combination) in soil column microcosms contaminated with 2,6-DCP. The 2,6-DCP biodegradation data fitted well to the first-order kinetic model. The model revealed that 2,6-DCP contaminated-soil microcosms amended with NPK fertilizer and PPAC (alone or in combination) had higher biodegradation rate constants (k) as well as lower half-life times (t1/2) than soil column microcosms amended with PKO and unamended soil (natural attenuation) remediation system. Thus, the use of combined NPK fertilizer and activated carbon (NPK + PPAC) to enhance 2,6-DCP degradation in the soil could be one of the severally sought bioremediation strategies of remediating natural ecosystem (environment) contaminated with organic chemicals.