Prof. Igor M. Belyakov

Midwest Research Institute, USA

Email: igorbelyakov@yahoo.com

Qualifications

1993 D.Sc., Russian Academy of Medical Sciences (RAMS), Russia

1986 Ph.D., Chelyabinsk State School of Medicine, Russia

1983 M.D., North-Osetian State School of Medicine, Russia

Publications (selected)

1. Kisakov, D. N., Belyakov, I. M., Kisakova, L. A., Yakovlev, V. A., Tigeeva, E. V., & Karpenko, L. I. (2024). The use of electroporation to deliver DNA-based vaccines. Expert Review of Vaccines, 23(1), 102-123.
2. Reguzova, A. Y., Karpenko, L. I., Mechetina, L. V., & Belyakov, I. M. (2015). Peptide–MHC multimer-based monitoring of CD8 T-cells in HIV-1 infection and AIDS vaccine development. Expert review of vaccines, 14(1), 69-84.
3. Karpenko, L. I., Bazhan, S. I., Antonets, D. V., & Belyakov, I. M. (2014). Novel approaches in polyepitope T-cell vaccine development against HIV-1. Expert review of vaccines, 13(1), 155-173.
4. Smirnov, N. N., Betelin, V. B., Shagaliev, R. M., Nikitin, V. F., Belyakov, I. M., Deryuguin, Y. N., ... & Korchazhkin, D. A. (2014). Hydrogen fuel rocket engines simulation using LOGOS code. International Journal of Hydrogen Energy, 39(20), 10748-10756.
5. Zhu, Q., Talton, J., Zhang, G., Cunningham, T., Wang, Z., Waters, R. C., ... & Berzofsky, J. A. (2012). Large intestine–targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nature medicine, 18(8), 1291-1296.
6. Makidon, P. E., Belyakov, I. M., Blanco, L. P., Janczak, K. W., Landers, J., Bielinska, A. U., ... & Baker Jr, J. R. (2012). Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cell trafficking. European journal of immunology, 42(8), 2073-2086.
7. Zhu Q, Egelston C, Sui Y, Gagnon S, Belyakov I.M., Klinman DM, Berzofsky JA. Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T-cell responses needed for antiviral protection in mice. Journal of Clinical Investigation 2010;120(2):607-616. PMCID: PMC2811160
8. Sui Y, Zhu Q, Gagnon S, Dzutsev A, Terabe M, Vaccari M, Venzon D, Klinman D, Strober W, Kelsall B, Franchini G, Belyakov I.M., Berzofsky JA. Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques. Proc. Natl. Acad. Sci. USA
9. 2010; 107(21): 9843-9848. PMCID: PMC2906837
10. Mahajan B, Berzofsky JA, Boykins RA, Majam V, Zheng H, Chattopadhyay R, de la Vega P, Moch JK, Haynes JD, Belyakov I.M., Nakhasi HL, Kumar S. Multiple Antigen Peptide Vaccines against Plasmodium falciparum Malaria. Infection and Immunity 2010;78(11):4613-4624.
11. Sui Y, Gagnon S, Dzutsev A, Zhu Q, Yu H, Hogg A, Wang Y, Xia Z, Belyakov I.M., Venzon D, Klinman D, Strober W, Kelsall B, Franchini G, Berzofsky JA. TLR agonists and/or IL-15 adjuvanted mucosal SIV-vaccine reduced gut CD4+ memory T cell loss in SIVmac251-challenged rhesus macaques. Vaccine 2011; 30(1): 59-68.
12. Isakov D, Dzutsev A, Berzofsky JA, Belyakov I.M. † Lack of IL-7 and IL-15 signaling affects interferon-gamma production by, more than survival of, small intestinal intraepithelial memory CD8+ T cells. European Journal of Immunology 2011; 41(12): 3513-3528. †Corresponding author.
13. Zhu Q., Talton J., Zhang G., Cunningham T., Wang Z., Waters R.C., Kirk J., Epper B., Klinman D.M., Sui Y., Gagnon S., Belyakov I.M., Mumper R.J., & Berzofsky J.A., 2012. Large intestine-targeted, nanoparticle-releasing oral vaccine to control genitorectal viral infection. Nature Medicine 2012; 18(8): 1291-1296. doi: 10.1038/nm.2866.
14. Makidon P.E., Belyakov I.M., Blanco L.P., Janczak K.W., Landers J., Bielinska A.U., Groom J.V., and Baker J.R. Nanoemulsion mucosal adjuvant uniquely activates cytokine production by nasal ciliated epithelium and induces dendritic cells trafficking. European Journal of Immunology 2012; 42: 2071-2086. Igor M. Belyakov 6/4/2015 13
15. Makidon, P. E., Groom, J.V. II, Smith, D., Ciotti S., Cao, Z., Landers, J., Hassani A., Orr N., Belyakov, I.M., and Baker, J.R. Jr. Nanoemulsion-adjuvanted vaccine for HBV induces robust antibody and CD8+ T cell immune responses in mice immunosuppressed from chronic kidney disease. Clinical and Vaccine Immunology 2014.
16. Dzutsev A., Koo L., Hogg A., Schwartz O., Kabat J., Sui Y., Gagnon S., Belyakov I.M., Trinchieri G. and Berzofsky J.A. Dendritic cells patrol lamina propria and epithelium associated with colonic patches and uptake bacteria from the lumen of the colon.
17. Krotova O., Starodubova E., Petkov S., Kostic L., Agapkina J., Hallengärd D., Viklund A., Latyshev O., Gelius E., Dillenbeck T., Karpov V., Gottikh M., Belyakov I.M., Lukashov V., Isaguliants M.G. Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cells. PLoS One 2013; 8(5): e62720.

Profile Details

https://www.researchgate.net/profile/Igor-Belyakov
https://orcid.org/0000-0003-0648-1549