Dr. Wuguo Chen
Lineberger Comprehensive Cancer Center
Department of Microbiology and Immunology
University of North Carolina at Chapel Hill, USA
Email: wuguo_chen@med.unc.edu
Qualifications
2006 PH.D., Life Science College of Wuhan University, China
2002 M.S., Central China Normal University, China
Publications (Selected)
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Wang, Z., Long, M., Sun, P., Zhang, Y., Chen, W., & Jia, D. (2025). Surface Defect Identification of Strip Steel Using ViT‐RepVGG. steel research international, 96(3), 2400569.
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Angius, F., Piras, E., Uda, S., Madeddu, C., Serpe, R., Bigi, R., ... & Ingianni, A. (2017). Antimicrobial sulfonamides clear latent Kaposi sarcoma herpesvirus infection and impair MDM2–p53 complex formation. The Journal of antibiotics, 70(9), 962-966.
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Zhang, Z., Chen, W., Sanders, M. K., Brulois, K. F., Dittmer, D. P., & Damania, B. (2016). The K1 protein of Kaposi's sarcoma-associated herpesvirus augments viral lytic replication. Journal of virology, 90(17), 7657-7666.
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Drancourt, M., Baquero, F., Denis, F., de Lamballerie, X., Letaief, A., de Souza, W., ... & Yang, R. (2014). New Microbes and New Infections. New Microbes and New Infections, 2(1), i.
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Yang, D., Chen, W., Xiong, J., Sherrod, C. J., Henry, D. H., & Dittmer, D. P. (2014). Interleukin 1 receptor-associated kinase 1 (IRAK1) mutation is a common, essential driver for Kaposi sarcoma herpesvirus lymphoma. Proceedings of the National Academy of Sciences, 111(44), E4762-E4768.
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Chen, W., Sin, S. H., Wen, K. W., Damania, B., & Dittmer, D. P. (2012). Hsp90 inhibitors are efficacious against Kaposi Sarcoma by enhancing the degradation of the essential viral gene LANA, of the viral co-receptor EphA2 as well as other client proteins. PLoS pathogens, 8(11), e1003048.
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Chen, W., & Dittmer, D. P. (2011). Ribosomal protein S6 interacts with the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus. Journal of virology, 85(18), 9495-9505.
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Chen, W., Hilton, I. B., Staudt, M. R., Burd, C. E., & Dittmer, D. P. (2010). Distinct p53, p53: LANA, and LANA complexes in Kaposi's sarcoma-associated herpesvirus lymphomas. Journal of virology, 84(8), 3898-3908.
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Dong, C., Zhang, J., Huang, H., Chen, W., & Hu, Y. (2009). Pathogenicity of a new China variety of Metarhizium anisopliae (M. Anisopliae var. Dcjhyium) to subterranean termite Odontotermes formosanus. Microbiological research, 164(1), 27-35.
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Chen, W., Hu, Y., Li, Y., Yu, Z., Dong, C., Cai, D., & Zhang, J. (2007). Characterization of the RNA-binding regions in protein p36 of Heliothis armigera cypovirus 14. Virus research, 125(2), 211-218.
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Li, Y., Zhang, J., Li, Y., Tan, L., Chen, W., Luo, H., & Hu, Y. (2007). Phylogenetic analysis of Heliothis armigera cytoplasmic polyhedrosis virus type 14 and a series of dwarf segments found in the genome. Journal of general virology, 88(3), 991-997.
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Dong, C., Zhang, J., Chen, W., Huang, H., & Hu, Y. (2007). Characterization of a newly discovered China variety of Metarhizium anisopliae (M. anisopliae var. dcjhyium) for virulence to termites, isoenzyme, and phylogenic analysis. Microbiological Research, 162(1), 53-61.
Profile Details
WoS ResearcherID: C-6084-2014
https://www.med.unc.edu/genetherapy/directory/wuguo-chen/
https://www.linkedin.com/in/wuguo-chen-6493625b/