Dr. Robert A. Drewell

Harvey Mudd College, Canada

Email: drewell@hmc.edu

Qualifications

2011 Associate Professor, Harvey Mudd College
1999 Ph.D., University of Cambridge, Molecular & Developmental Biology
1996 B.Sc., University of London, Molecular Genetics

Publications (Selected)

1. DNA methylation in social insects: an emerging role in form and function.R. A. Drewelland B. P. Oldroyd.Submitted.
2. Transcriptional repression by the proximal exonic region at the humanTERTgene.T. C. Wong, E. S. Sokol, A. N. Schep, M. Punjiya, D. A. Tran, D. Allen andR. A. Drewell.Submitted.
3. Molecular dissection ofcis-regulatory modules at theDrosophilabithorax complex reveals critical transcription factor signature motifs.M. O. Starr, M. C. W. Ho, E. J. M. Gunther, Y. K. Tu, A. S. Shur, S. E. Goetz, M. J. Borok , V. Kang andR. A. Drewell.Submitted.
4. Disruption of theAbdominal-Bpromoter tethering element results in a loss of long-range enhancer-directed Hox gene expression inDrosophila.M. C. W. Ho, B. J. Schiller , O. S. Akbari, E. Bae andR. A. Drewell.2011.PLoS One6: e16283.
5. Characterization of an ultra-conserved putativecis-regulatory module at the mammalian telomerase reverse transcriptase gene.D. A. Tran, T. C. Wong, A. N. Schep andR. A. Drewell.2010.DNA and Cell Biology29: 499-508.
6. Dissecting the regulatory switches of development: Lessons from enhancer evolution inDrosophila.M. J. Borok, D. A. Tran, M. C. W. Ho andR. A. Drewell.2010.Development137:5-13.
7. Functional evolution ofcis-regulatory modules at a homeotic gene inDrosophila.M. C. W. Ho, H. Johnsen, S. E. Goetz, B. J. Schiller, E. Bae, D. A. Tran, A. S. Shur, J. M. Allen, C. Rau , W. Bender, W. W. Fisher, S. E. Celniker andR. A. Drewell.2009.PLoS Genetics5: e1000709.
8. Non-genic transcription at theDrosophilabithorax complex – functional activity of the dark matter of the genome.M. C. W. Ho, B. J. Schiller, S. E. Goetz andR. A. Drewell.2009.International Journal of Developmental Biology53: 459-468.
9. A conciseDrosophilalaboratory module to introduce the central concepts of genetics.M. C. W. Ho , D. R. Venema andR. A. Drewell.2008.Drosophila Information Service91: 164-168.
10. Between transcription and translation: re-defining RNA and regulation.M. C. W. Ho, B. J. Schiller, S. E. Goetz, J. M. Allen andR. A. Drewell.2008.Fly2: 152-155.
11. A novel promoter tethering element regulates enhancer-driven gene expression at the bithorax complex in theDrosophilaembryo.O. S. Akbari, E. Bae, H. Johnsen, A. Villaluz, D. Wong andR. A. Drewell.2008.Development135: 123-131.
12. TheAbdominal-Bpromoter tethering element mediates promoter-enhancer specificity at theDrosophilabithorax complex.O. S. Akbari, B. J. Schiller, S. E. Goetz, M. C. W. Ho, E. Bae andR. A. Drewell.2007.Fly1: 337-339
13. Chromatin looping mediates boundary element promoter interactions.S. Celniker andR. A. Drewell.2007.Bioessays29: 7-10.
14. The human and mouseH19imprinting control regions harbor an evolutionarily conserved silencer element that functions on transgenes inDrosophila.K. L. Arney, E. Bae, C. E. Olsen andR. A. Drewell.2006.Development, Genes and Evolution216: 811-819.
15. Unravelingcis-regulatory mechanisms at theabdominal-AandAbdominal-Bgenes in the Drosophila bithorax complex.O. S. Akbari, A. Bousum, E. Bae andR. A. Drewell.2006.Developmental Biology293: 294-304.
16. The 3’ portion of the mouseH19Imprinting-Control Region is required for proper tissue-specific expression of theIgf2gene.H. Hagège, R. Nasser, M. Weber, L. Milligan, N. Aptel, C. Jacquet,R.A. Drewell, L. Dandolo, M.A. Surani, G. Cathala, T. Forné.2006.Cytogenetic & Genome Research113: 230-237.
17. Transcription defines the embryonic domains ofcis-regulatory activity at theDrosophilabithorax complex.R. A. Drewell, E. Bae, J. Burr and E. B. Lewis.2002.Proceedings of the National Academy of Sciences USA99: 16853-16858.
18. Characterization of the intergenic RNA profile atabdominal-AandAbdominal-Bin theDrosophilabithorax complex.E. Bae, V. C. Calhoun, M. Levine, E. B. Lewis andR. A. Drewell.2002.Proceedings of the National Academy of Sciences USA99: 16847-16852.
19. Novel conserved elements upstream of theH19gene are transcribed and act as mesoderm enhancers.R. A. Drewell, K. L. Arney, T. Arima, S. C. Barton, J. D. Brenton and M. A. Surani.2002.Development129: 1205-1213
20. Methylation-dependent silencing at theH19imprinting control region by MeCP2.R. A. Drewell, C. J. Goddard, J. O. Thomas and M. A. Surani.2002.Nucleic Acids Research30: 1139-1144

Profile Details

https://www.clarku.edu/faculty/profiles/robert-drewell/
https://scholar.google.com/citations?user=zu-jPH4AAAAJ&hl=en