Dr. Rahul Mahavir
Nandre
NIH National Center for Advancing Translational Sciences (NCATS), USA
Toxicologist
Email: rahulbiotech@gmail.com
Qualifications
2013 Ph.D., Chonbuk National
University, South Korea; Veterinary Medicine
2007 M.Sc., Anand Agricultural
University, India; Animal Biotechnology
2005 D.V.M., Bombay Veterinary
College, India; Veterinary Medicine
Publications (Selected)
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Nandre, R. M., Newman, A. H., & Terse, P. S. (2024). In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder. PloS one, 19(12), e0315569.
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Nandre, R. M., & Terse, P. S. (2024). An overview of immunotoxicity in drug discovery and development. Toxicology Letters.
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Nandre, R., Verma, V., Gaur, P., Patil, V., Yang, X., Ramlaoui, Z., ... & Khleif, S. N. (2022). IDO vaccine ablates immune-suppressive myeloid populations and enhances antitumor effects independent of tumor cell IDO status. Cancer immunology research, 10(5), 571-580.
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Verma, V., Jafarzadeh, N., Boi, S., Kundu, S., Jiang, Z., Fan, Y., ... & Khleif, S. N. (2021). MEK inhibition reprograms CD8+ T lymphocytes into memory stem cells with potent antitumor effects. Nature immunology, 22(1), 53-66.
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Verma, V., Shrimali, R. K., Ahmad, S., Dai, W., Wang, H., Lu, S., ... & Khleif, S. N. (2019). PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+ CD38hi cells and anti-PD-1 resistance. Nature immunology, 20(9), 1231-1243.
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Verma, V., Shrimali, R. K., Ahmad, S., Dai, W., Wang, H., Lu, S., & Nandre, R. (2019). Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1. sup.+ CD38. sup. hi cells and anti-PD-1 resistance. Nature immunology, 20(11), 1555-1556.
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Verma, V., Shrimali, R. K., Ahmad, S., Dai, W., Wang, H., Lu, S., ... & Khleif, S. N. (2019). PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+ CD38hi cells and anti-PD-1 resistance. Nature immunology, 20(9), 1231-1243.
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Duan, Q., Xia, P., Nandre, R., Zhang, W., & Zhu, G. (2019). Review of newly identified functions associated with the heat-labile toxin of enterotoxigenic Escherichia coli. Frontiers in cellular and infection microbiology, 9, 292.
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Seo, H., Nandre, R. M., Nietfeld, J., Chen, Z., Duan, Q., & Zhang, W. (2019). Antibodies induced by enterotoxigenic Escherichia coli (ETEC) adhesin major structural subunit and minor tip adhesin subunit equivalently inhibit bacteria adherence in vitro. PLoS One, 14(5), e0216076.
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Seo, H., Lu, T., Nandre, R. M., Duan, Q., & Zhang, W. (2019). Immunogenicity characterization of genetically fused or chemically conjugated heat-stable toxin toxoids of enterotoxigenic Escherichia coli in mice and pigs. FEMS microbiology letters, 366(4), fnz037.
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Gaur, P., Verma, V., Nandre, R., Vir, P., Wang, H., Kang, B., ... & Khleif, S. N. (2018). Histone deacetylase inhibitor, Entinostat enhances the tumor specific immune response by generating T-cell central memory in the TME. Cancer Research, 78(13_Supplement), 3761-3761.
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Nandre, R., Verma, V., Gaur, P., Vir, P., Wang, H., Kang, B., ... & Khleif, S. (2018). IDO vaccine enhances antigen-specific anti-tumor effects by reducing IDO-expressing antigen presenting cells and MDSCs. Cancer Research, 78(13_Supplement), 3763-3763.
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Duan, Q., Lu, T., Garcia, C., Yañez, C., Nandre, R. M., Sack, D. A., & Zhang, W. (2018). Co-administered tag-less toxoid fusion 3xSTaN12S-mnLTR192G/L211A and CFA/I/II/IV MEFA (multiepitope fusion antigen) induce neutralizing antibodies to 7 adhesins (CFA/I, CS1-CS6) and both enterotoxins (LT, STa) of enterotoxigenic Escherichia coli (ETEC). Frontiers in microbiology, 9, 1198.
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Nandre, R., Ruan, X., Lu, T., Duan, Q., Sack, D., & Zhang, W. (2018). Enterotoxigenic Escherichia coli adhesin-toxoid multiepitope fusion antigen CFA/I/II/IV-3xSTaN12S-mnLTG192G/L211A-derived antibodies inhibit adherence of seven adhesins, neutralize enterotoxicity of LT and STa toxins, and protect piglets against diarrhea. Infection and immunity, 86(3), 10-1128.
Profile Details
WoS ResearcherID: AAR-5503-2020
https://www.linkedin.com/in/dr-rahul-nandre-dvm-ms-phd/
https://scholar.google.com.hk/citations?hl=zh-CN&user=ND0EGX8AAAAJ
https://www.researchgate.net/profile/Rahul-Nandre