National Institutes of Health (NIH), USA

Email: kumarp1978@yahoo.com

Qualifications

2007 Ph.D., Chaudhary Charan Singh University in collaboration with University of Delhi, India

2000 M.Sc., Chaudhary Charan Singh University, India

1998 B.Sc., Chaudhary Charan Singh University, India

Publications (selected)

1. I. Kira Astakhova, Karol pasternak, Meghan Campbell, Pankaj Gupta and Jesper Wengel. “A Locked Nucleic Acid-Based Nanocrawler: Designed and Reversible Movement Detected by Multicolor Fluorescence” J. Am. Chem. Soc.2013,135, 2423–2426.
2. Thomas Zengeya, Pankaj Gupta and Eriks Rozners. “Triple Helical Recognition of RNA Using 2-Aminopyridine-Modified PNA at Physiologically Relevant Conditions” Angew. Chem.2012,51, 12593-12596.
3. Pankaj Gupta, Toyosi Muse and Eriks Rozners. “Recognition of Double Stranded RNA by Guanidine-Modified Peptide Nucleic Acids (GPNA)” Biochemistry2012,51, 63-73.
4. Pankaj Gupta, Thomas Zengeya and Eriks Rozners. “Triple Helical Recognition of Pyrimidine Inversions in Polypurine Tracts of RNA by Nucleobase-modified PNA” Chem. Commun., 2011,47, 11125-11127.
5. Pankaj Gupta, Sumati Bhatia, Ashish Dhawan, Sakshi Balwani, Shatrughan Sharma, Raju Brahma, Rajpal Singh, Balaram Ghosh,Virinder S.Parmar andAshok K. Prasad.“Selective biocatalytic aminolysis of (±)-epichlorohydrin: Synthesis and ICAM-1 inhibitory activity of (S)-(+)-3-arylamino-1-chloropropan-2-ols” Bioorg. Med. Chem.2011,19, 2263-2268.
6. Karol Pasternak, Anna Pasternak, Pankaj Gupta, Rakesh Veedu and Jesper Wengel. “Photoligation of self-assembled DNA constructs containing anthracene-functionalized 2'-amino-LNA monomers” Bioorg. Med. Chem.2011,19, 7407-7415.
7. Eman Zaghloul, Andreas Madsen, Pedro Moreno, Iulian Oprea, Samir EL-Andaloussi, Burcu Bestas, Pankaj Gupta, Erik Pedersen, Karin Lundin, Jesper Wengel and Edvard Smith. “Optimizing anti-gene oligonucleotide“Zorro-LNA” for improved strand-invasion into duplex DNA” Nucleic Acid Res. 2011,39, 1142-1154.
8. Benjamin L. Parker, Pankaj Gupta, Stuart J. Cordwell,Martin R. Larsen and Giuseppe Palmisano. “Purification and identification ofO-GlcNAc modified peptides using phosphate-based alkyne CLICK chemistry in combination with titanium dioxidechromatography and accurate mass spectrometry” J. Proteome Res. 2011,10, 1449-1458.
9. Pankaj Gupta, Niels Langkjær and Jesper Wengel. “Synthesis and biophysical studies of coronene functionalized 2'-amino-LNA: a novel class of fluorescent nucleic acids” Bioconjugate Chem.2010,21, 513-520.
10. Pankaj Gupta, Sakshi Balwani,Sarvesh Kumar, Neha Aggarwal, Miriam Rossi, Sarah Paumier, Francesco Caruso, Paolo Bovicelli, Luciano Sasso, Anthony L.DePass, Ashok K. Prasad, Virinder S. Parmar and Balaram Ghosh. “β-sitosterol among other secondary metabolites ofPiper galeatumshows inhibition of TNFα-induced cell adhesion molecule expression on human endothelial cells” Biochimie2010,92,1213-1221.
11. Pankaj Gupta, Jyotirmoy Maity,Gaurav Shakya, Ashok K Prasad, Virinder S Parmarand Jesper Wengel. “Synthesis and hybridization studies of -configured arabino nucleic acids” Org. Biomol. Chem.2009,7, 2389-2401.
12. Ashok K. Prasad,Pankaj Kumar,Ashish Dhawan, Anil K. Chhillar, Deepti Sharma, Vibha Yadav, Manish Kumar,Hirday N. Jha, Carl E. Olsen, Gainda L. Sharma and Virinder S. Parmar. “Synthesis and antimicrobial activity of novel 3-Arylamino-1-chloropropan-2-ols” Bioorg. Med. Chem.Lett.2008,18, 2156-2161.
13. Anil K. Chhillar, Pragya Arya, Chandrani Mukherjee,Pankaj Kumar, Yogesh Yadav, Vibha Yadav, Jyotsana Gupta, Rajesh Dabur, Hirday N. Jha, Ashok K. Prasad, Virinder S. Parmar and Gainda L. Sharma. “Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: noval compounds against Aspergillosis” Bioorg. Med. Chem.2006,14, 973-981.
14. Kunya Danprasert, Rajesh Kumar, Ming H-Cheng, Pankaj Gupta, Najam A Shakil, Ashok K Prasad, Virinder S Parmar, Jayant Kumar, Lynne A Samuelson and Arthur C Watterson. “Synthesis of novel poly (ethylene glycol) based amphiphilic polymers” Eur. Poly. J.2003,39, 1983-1990.

15. Shanghui Hu, Pankaj Gupta, Ashok K Prasad, Richard A Gross and Virinder S. Parmar. “Selective enzymatic epoxidation of dienes: generation of functional enantiomerically enriched diene monoepoxy monomers” Tetrahedron Letts.2002, 43,6763-6766.

16. Pankaj Gupta and Daniel H. Appella. “Synthesis of Pyrrole Derivatives for Selective Inhibition of Wip1 Phosphatase” Abstracts of Papers, 244th ACS National Meeting & Exposition, Philadelphia, PA, United States, August 19-August 23, 2012.

17. Eriks Rozners, Thomas Zengeya, Pankaj Gupta and Ming Li. “Sequence selective recognition of microRNAs using chemically modified peptide ncleic acids” Abstracts of Papers, 242nd ACS National Meeting & Exposition, Denver, CO, United States, August 28-September 1, 2011.

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