The Graduate Center for Toxicology

The Markey Cancer Center

University of Kentucky College of Medicine, USA

Assistant Professor

Email: qiou.wei@uky.edu

Qualifications

2005 Ph.D., University of South Dakota Sanford School of Medicine, Biochemistry and Molecular Biology

1997 M.M., Chongqing Medical University, Infectious Disease

1994 M.D., Chongqing Medical University

Publications (Selected)

1. Wei Q, Jiang H, Baker A, Dodge LK, Gerard M, Young MR, Toledano MB, Colburn NH. 2013. Loss of Sulfiredoxin renders mice resistance to AOM/DSS induced colon carcinogenesis. Carcinogenesis (in press).
2. Wei Q, Jiang H, Xiao Z, Baker A, Young MR, Veenstra TD, Colburn NH*. 2011. The Srx-PrxIV axis promotes human lung cancer progression through modulation of specific phosphokinase signaling pathways. Proc. Natl. Acad. Sci. USA 108 (17):7004-9.
3. Wei Q, Jiang H, Matthews CP, Colburn NH. 2008. Sulfiredoxin is an AP-1 target gene that is required for transformation and shows elevated expression in human skin malignancies. Proc. Natl. Acad. Sci. USA 105 (50): 19738-19743.
4. Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X. 2007. R-spondin1 is a high affinity ligand for LRP6 and induces phosphorylation of LRP6 and activation of the b-catenin pathway. J. Biol. Chem. 282 (21): 15903-15911. (Featured as Editor’s Choice on Science Signaling STKE, Vol. 2007, Issue 388, p. tw188)
5. Wei Q, Eviatar-Ribak T, Miskimins WK, Miskimins R. 2007. Galectin-4 is involved in p27-mediated activation of the myelin basic protein promoter. J. Neurochem 101 (5): 1214-1223.
6. Wei Q, Miskimins WK, Miskimins R. 2005. Stage-specific Expression of Myelin Basic Protein in oligodendrocytes involves Nkx2.2-mediated repression that is relieved by Sp1 family of transcription factors. J. Biol. Chem. 280 (16): 16284-1694.
7. Wei Q, Miskimins WK, Miskimins R. 2004. Sox10 Acts as a Tissue-Specific Transcription Factor Enhancing Activation of the Myelin Basic Protein Gene Promoter by p27Kip1 and Sp1. J. Neurosci. Res. 78 (6): 796-802.
8. Wei Q, Miskimins WK, Miskimins R. 2003. The Sp1 family of transcription factors is involved in p27(Kip1)-mediated activation of myelin basic protein gene expression. Mol. Cell Biol. 23 (12): 4035-4045.
9. Wei Q, Miskimins WK, Miskimins R. 2003. Cloning and characterization of the rat myelin basic protein gene promoter. Gene 313: 161-167.
10. Chen G, Qiu X, Lu X, Pei Y, Wei Q, Cheng J. 2003. Inhibition property of a polypeptide APS against phytopathogenic fungi and the possible antifungal mechanism. Sichuan Da Xue Xue Bao Yi Xue Ban 34 (2): 220-222.
11. Yang Z, Wei R, Xiang Z, Xie H, Wei Q. 2001. Experimental study on tumorigenicity of human embryonic tendon cell transformed by ptsA58H plasmid. Chinese J. Microsurgery 24 (1): 36-39.
12. Huang J, Cheng L, Yue Y, Wei Q. 2000. In vitro study of C3a des Arg produced by plasma incubation with blood purification materials. J. Biomed. Engr. 17 (4): 385-389.
13. Bu H, Wang H, Wei Q. 2000. The xenoantigenicity of Chinese inbred-line pigs. Chinese J. Reparative & Reconstructive Surgery 14 (2): 115-118, 2000.
14. Jiang H, Wei Q, Fu H. 2000. Upregulation of ICAM-1 expression enhances cytotoxic sensitivity of tumor cells to LAK by LTA from bifidobacterium. Immunological J. 16 (6): 429-431.
15. Wei Q, Jiang H, Lu X. 1999. A molecular epidemiology study on nosocomial urinary tract infection in urology patients with chronic indwelling urethral catheters. Chinese J. Nosocomiology 9(3): 137-139.
16. Yang Z, Xie H, Xiang Z, Li S, Wei Q. 1999. Culture of the transformed human embryonic tendon cells and its biological characteristics in vitro. Chinese J. Reparative & Reconstructive Surgery 13 (2): 115-118.
17. Wei Q, Peng Y, Cheng J. 1999. Determination of Neijiang pig’s serum antipyrine concentration by micellar electrokinetic capillary chromatography (MEKC). J. West China Pharmacology. 14 (4): 277-280.
18. Wei Q, Cheng J, and Cai S. 1999. Rapid determination of cefazolin in porcine serum by high performance capillary electrophoresis. J. West China Univ. of Med. Sci. 30 (2): 120-122.
19. Jiang H, Fu H, Wei Q. 1999. The inhibitory effects of bifidobacterium bifidum on candida albicans infection in immunosupprised mice. Chinese J. Microecology 10 (2): 75-77, 1999.
20. Wei Q, Jiang H, Lu X. 1998. The investigation of nosocomial urinary tract infection in urology patients with chronic indwelling urethral catheters. Chinese J. Epidemiology. 19 (5B): 229-231, 1998.
21. Wei Q, Jiang H, Lu X. 1998. Molecular epidemiology of nosocomial urinary tract infection in urology patients with chronic indwelling urethral catheters. Chinese J. Epidemiology. 19 (5B): 55-60, 1998.
22. Wei Q, Lu X. 1997. Combined typing methods of pseudomonas aeruginosa and applications in nosocomial infection. Acta Univ. Sci. Med. Chongqing 2 (22): 102-105.