Dr. Kazuhisa Nishizawa

NIK Biomolecular Research Group, Japan

Professor

Email: kazu.nishizawa.nik@gmail.com

Qualifications

1994 Ph.D., Doctor of Medicine (Basic Medical Science, Physiology)

1989 M.D., National Medical Doctor License

1989 M.Sc.,The University of Tokyo School of Medicine

Publications(selected)

1. Nishizawa, M., & Nishizawa, K. (2025). A simulation analysis of the effect of a cholesterol-dependent fusogenic peptide from HIV gp41 on membrane phospholipid dynamics. Biochimica et Biophysica Acta (BBA)-Biomembranes, 184413.
2. Kuramata, H., Hashiba, M., Kai, Y., Nishizawa, K., Inoue, T., Kikuchi-Ueda, T., ... & Oshikane, H. (2022). Animal Species Identification Utilising DNAs Extracted from Traditionally Manufactured Gelatin.
3. Kuramata, H., Hashiba, M., Kai, Y., Nishizawa, K., Inoue, T., Kikuchi-Ueda, T., ... & Oshikane, H. (2022). Animal species identification utilising DNAs extracted from traditionally manufactured gelatin (Wanikawa). Heritage Science, 10(1), 183.
4. Nishizawa, K., & Seki, R. (2020). Epidemiological studies of uric acid: a mini-review with a focus on Mendelian randomization. Annals of Biomedical Research, 3, 119.
5. Reiko, S. E. K. I., & Nishizawa, K. (2020). Use of TLR9 and TLR7/8 agonists in combination with d-galactosamine in exploring models for distinct severities of systemic inflammation relative to liver injury. Physiological Research, 69(6), 1125.
6. Nishizawa, K., & Nishizawa, M. (2019). Atomistic simulation analyses of sequence-nonspecific effects of lipid composition on transmembrane helical peptide dimerization. Annals of Biomedical Research, 2(1), 114.
7. Seki, R., & Nishizawa, K. (2019). Shikonin: a review with a focus on anti-inflammatory and anticancer mechanisms. Annals of Biomedical Research, 2(1), 115.
8. Kawanabe, A., Hashimoto, M., Nishizawa, M., Nishizawa, K., Narita, H., Yonezawa, T., ... & Okamura, Y. (2018). The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase. Elife, 7, e41653.
9. Gnanasambandam, R., Ghatak, C., Yasmann, A., Nishizawa, K., Sachs, F., Ladokhin, A. S., ... & Suchyna, T. M. (2017). GsMTx4: mechanism of inhibiting mechanosensitive ion channels. Biophysical journal, 112(1), 31-45.
10. Nishizawa, M., Chonabayashi, K., Nomura, M., Tanaka, A., Nakamura, M., Inagaki, A., ... & Yoshida, Y. (2016). Epigenetic variation between human induced pluripotent stem cell lines is an indicator of differentiation capacity. Cell stem cell, 19(3), 341-354.
11. Nishizawa, K. (2016). Low-grade endotoxemia, diet, and gut microbiota–an emphasis on the early events leading to dysfunction of the intestinal epithelial barrier. Biomed Res Clin Pract, 1(2), 46-57.
12. Nishizawa M and Nishizawa K,Molecular dynamics simulation analysis of membrane defects and pore propensity of hemifusion diaphragmsBiophysical Journal,104:1038–1048,(2013)
13. Nishizawa M and Nishizawa K,Coarse-grained simulations of branched bilayer membranes -- Effects of cholesterol-dependent phase separation on curvature-driven lipid sortingJ Biophys Chem2: 268-284 (2011)DOI: 10.4236/jbpc.2011.23032
14. Nishizawa M, Nishizawa K.Curvature-driven lipid sorting: coarse-grained dynamics simulations of a membrane mimicking a hemifusion intermediate.J Biophys Chem(2010)1:86-95
15. Nishizawa M, Nishizawa K.Molecular dynamics simulation analyses of stalk-inducing effect of viral fusion peptides: importance of oblique orientation in membranes.J Biophys Chem(2010)1:19-32
16. Nishizawa M, Nishizawa K.Coupling of S4 helix Translocation and S6 Gating Analyzed by Molecular Dynamic Simulations of Mutated Kvchannels.Biophys J(2009)97: 90-100
17. Nishizawa M, Nishizawa K.Molecular Dynamics Simulation of Kv channel Voltage Sensor Helix in a Lipid Membrane with Applied Electric Field.Biophys J(2008)95:1729-1744
18. Nishizawa M, Nishizawa K.Molecular Dynamics Simulations of a Stretch-Activated Channel Inhibitor GsMTx4 with Lipid Membranes: Two Binding Modes and Effects of Lipid Structure.Biophys J(2007)92: 4233-4243
19. Nishizawa M,Nishizawa K.A DNA sequence evolution analysis generalized by simulation and the Markov chain Monte Carlo method implicates strand slippage in a majority of insertions and deletions.
20. J Mol Evol.55: 706-717.(2002).
21. Nishizawa M,Nishizawa K.Amino acid and nucleotide recurrence in aligned sequences: synonymous substitution patterns in association with global and local base compositionsNucleic Acids Res.28: 3801-3810. (2000).
22. Kazuhisa Nishizawa, Christian Freund, Jing Li, Gerhard Wagner and Ellis L.Reinherz.Identification of a novel proline-binding motif regulating CD2-triggered T lymphocyte activation.Proc Natl Acad Sci USA95,14897-902.(1998).

Profile Details

http://gen.g.dgdg.jp/pub.html
https://researchmap.jp/read0044952
https://orcid.org/0000-0002-7642-6054