Biography

Dr. Bor Luen Tang,

Dept. Biochemistry, National University of Singapore, Singapore

Associate Professor

 

Email:  bchtbl@nus.edu.sg

Qualifications

1994     Ph.D., National University of Singapore, Singapore

1991     M.Sc., Biochemistry, National University of Singapore, Singapore
1988     B.Sc., Biochemistry,National University of Singapore, Singapore


Publications

  1. Chen Y, Hor HH and Tang BL. AMIGO is expressed in multiple brain cells types and may regulate dendritic growth and neuronal survival. J. Cell Physiol. (in press) (doi: 10.1002/jcp.22958). 
  2. Gee HY, Roh SH, Tang BL, Kim KH, and Lee MG. Rescue of DF508-CFTR trafficking via a GRASP-dependent unconventional secretion pathway. Cell 146: 746-760. 
  3. Chua CE, Gan BQ and Tang BL (2011) Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation. Cell Mol. Life Sci. 68: 3349-3358. 
  4. Chua CE and Tang BL (2011) Rabs, SNAREs and α-synuclein - membrane trafficking defects in synucleinopathies. Brain Res. Rev. 67: 268-281. 
  5. Lim YS, Chua CE and Tang BL (2011) Rabs and other small GTPases in ciliary transport. Biol. Cell 103: 209-221.
  6. Tang BL, Gee HY and Lee MG (2011) The cystic fibrosis transmembrane conductance regulator (CFTR)’s expanding SNARE interactome. Traffic 12: 364-371. 
  7. Chen Y and Tang BL (2011) Unique intracellular trafficking processes associated with NCAM and its intracellular signaling. Cell Adh. Migr. 17:69-74. 
  8. Tang BL (2011) Sirt1's systemic protective roles and its promise as a target in anti-aging medicine. Trans. Res. 157: 276-284. 
  9. Huang TH, Tsui HA, Tang BL, Hu KY and Chen A (2011) Emerging roles of Rab23 in the pathophysiology of mesangial cells – a proteomic analysis. Proteomics 11:380-394. 
  10. Teng FY and Tang BL (2010) NF-қB signaling in neurite growth and neuronal survival. Rev. Neurosci. 21: 299-313. 
  11. Gee HY, Tang BL, Kim KH and Lee MG (2010) Syntaxin 16 binds to CFTR and regulates its membrane trafficking in epithelial cells. J. Biol. Chem. 285: 35519-35527. 
  12. Meng J, Xia W, Tang J, Tang BL and Liang F (2010) Dephosphorylation dependent inhibitory activity of juxtanodin on filamentous actin disassembly. J. Biol. Chem. 285: 28838-28849. 
  13. Ong YS, Tang BL, Loo LS and Hong W (2010) p125A exists as part of the mammalian Sec13-Sec31 COPII subcomplex to facilitate ER-Golgi transport, J. Cell Biol. 190: 331-345. 
  14. Chen Y, Gan BQ and Tang BL (2010) Syntaxin 16: unravelling cellular physiology through a ubiquitous SNARE molecule. J. Cell. Physiol. 225:326-332. 
  15. Gan BQ and Tang BL (2010) Sirt1’s beneficial roles in neurodegenerative diseases – a CCT connection? Aging Cell 9:924-929.
  16. Tang BL (2010) Is Rab25 a tumor promoter or suppressor – context dependency on RCP status? Tumor Biol. 31: 359-361. 
  17. Tang BL (2010) Resveratrol is neuroprotective because it is not a direct activator of Sirt1 - a hypothesis. Brain Res. Bull. 81:359-361. 
  18. Chua CE, Lim YS and Tang BL (2010) Rab35 – a vesicular traffic regulating small GTPase with actin modulating roles, FEBS Lett. 584: 1-6. 
  19. Tang BL and Chua CE (2010) Is systemic activation of Sirt1 beneficial for ageing-associated metabolic disorders? Biochem. Biophys. Res. Commun. 391: 6-10. 
  20. Ng EL, Ng JJ, Liang F and Tang BL (2009) Rab22B is expressed in the CNS astroglia lineage and plays a role in epidermal growth factor receptor trafficking in A431 cells. J. Cell. Physiol. 221: 716-728. 
  21. Tang BL (2009) Sirt1’s complex roles in neuroprotection. Cell. Mol. Neurobiol. 29: 1093-1103. 
  22. Ng EL and Tang BL (2009) Rabs and cancer cell motility. Cell Motil. Cytoskeleton 66: 365-370.
  23. Tang BL (2009) Neuronal protein trafficking associated with Alzheimer’s disease: from APP and BACE to glutamate receptors. Cell Adh. Migr. 3: 118-128 
  24. Chia WJ and Tang BL (2009) Emerging roles for Rab family GTPases in human cancer. Biochim. Biophys. Acta 1795: 110-116. 
  25. Huang TH, Shui HA, Ka SM, Tang BL, Chao TK, Chen JS, Lin YF and Chen A. (2009) Rab 23 is expressed in mesangial cells and plays a role in development of focal segmental glomerulosclerosis. Nephrol. Dial. Transplant 24: 743-754. 
  26. Teng FY, Hor CH and Tang BL (2009) Emerging cues mediating astroglia lineage restriction of progenitor cells in the injured/diseased adult CNS. Differentiation 77: 121-127. 
  27. Hou Q, Wu YH, Grabsch H, Zhu Y, Leong SH, Ganesan K, Cross D, Tan LK, Tao J, Gopalakrishnan V, Tang BL, Kon OL and Tan P (2008) Integrative genomic identify Rab23 as an invasion mediator gene in diffuse gastric cancer. Cancer Res. 68: 4623-4630.
  28. Teng FY and Tang BL (2008) Nogo-A and Nogo-66 receptor in amyotrophic lateral sclerosis. J. Cell. Mol. Med. 12: 1199-1204. 
  29. Ng EL and Tang BL (2008) Rab GTPases and their roles in brain neurons and glia. Brain Res. Rev. 58: 236-246.
  30. Teng FY and Tang BL (2008) Cell autonomous function of Nogo and reticulons - the emerging story at the endoplasmic reticulum. J. Cell.Physiol. 216: 303-308.
     
 
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