Biography

Prof. Azzam A. Maghazachi

Department of Physiology
University of Oslo, Norway


Email: azzam.maghazachi@medisin.uio.no


Qualifications

1984 Ph.D., Department of Immunology, University of Manitoba, Canada

1976 M.S., Department of Biology, New York University, USA


Publications (Selected)

  1. Kheder, W., Bouzid, A., Venkatachalam, T., Talaat, I. M., Elemam, N. M., Raju, T. K., Sheela, S., Jayakumar, M. N., Maghazachi, A. A., Samsudin, A. R., & Hamoudi, R. (2023). Titanium Particles Modulate Lymphocyte and Macrophage Polarization in Peri-Implant Gingival Tissues. International Journal of Molecular Sciences, 24(14), 11644. https://doi.org/10.3390/ijms241411644
  2. Noha M Elemam, Iman M Talaat, Azzam A Maghazachi; Dysregulation of natural killer cells’ receptor expression and cytotoxic function by hydroxychloroquine. J Immunol 1 May 2023; 210 (1_Supplement): 71.38. https://doi.org/10.4049/jimmunol.210.Supp.71.38
  3. Elemam, N.M., Maghazachi, A.A. (2023). Chemokines and Chemokine Receptors in Cancer: An Update. In: Rezaei, N. (eds) Handbook of Cancer and Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_26-1
  4. Anton Baysa, Azzam A. Maghazachi, Kristin Larsen Sand, Marika Campesan, Tania Zaglia, Marco Mongillo, Marco Giorgio, Fabio Di Lisa, Lars Gullestad, Lars H. Mariero, Jarle Vaage, Guro Valen, Kåre-Olav Stensløkken, Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein, Biochemical and Biophysical Research Communications, Volume 644, 2023, Pages 70-78, ISSN 0006-291X, https://doi.org/10.1016/j.bbrc.2022.12.085.
  5. Elemam NM, Youness RA, Hussein A, Shihab I, Yakout NM, Elwany YN, Manie TM, Talaat IM and Maghazachi AA (2022) Expression of GPR68, an Acid-Sensing Orphan G Protein-Coupled Receptor, in Breast Cancer. Front. Oncol. 12:847543. doi: 10.3389/fonc.2022.847543
  6. Shaista Manzoor, Maha Saber-Ayad, Azzam A. Maghazachi, Qutayba Hamid, Jibran Sualeh Muhammad, MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma, Neoplasia, Volume 24, Issue 2, 2022, Pages 76-85, ISSN 1476-5586, https://doi.org/10.1016/j.neo.2021.12.003.
  7. Wafaa Abumustafa, Batoul Abi Zamer, Bariaa A. Khalil, Mawieh Hamad, Azzam A. Maghazachi, Jibran Sualeh Muhammad, Protein arginine N-methyltransferase 5 in colorectal carcinoma: Insights into mechanisms of pathogenesis and therapeutic strategies, Biomedicine & Pharmacotherapy, Volume 145, 2022, 112368, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2021.112368.
  8. Elemam Noha Mousaad , Ramakrishnan Rakhee K. , Hundt Jennifer E. , Halwani Rabih , Maghazachi Azzam A. , Hamid Qutayba, Innate Lymphoid Cells and Natural Killer Cells in Bacterial Infections: Function, Dysregulation, and Therapeutic Targets, Frontiers in Cellular and Infection Microbiology, 11, 2021, https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2021.733564, ISSN 2235-2988, DOI: 10.3389/fcimb.2021.733564
  9. Dhaiban S, Al-Ani M, Elemam NM, Maghazachi AA. Targeting Chemokines and Chemokine Receptors in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis. J Inflamm Res. 2020;13:619-633, https://doi.org/10.2147/JIR.S270872
  10. Elemam, N.M., Al-Jaderi, Z., Hachim, M.Y. et al. HCT-116 colorectal cancer cells secrete chemokines which induce chemoattraction and intracellular calcium mobilization in NK92 cells. Cancer Immunol Immunother 68, 883–895 (2019). https://doi.org/10.1007/s00262-019-02319-7
  11. Maghazachi, A., Elemam, N. and Al-Jaderi, Z. (2018), HCT116 Colorectal Cancer Cells Secrete Chemokines Which Induce The Chemotaxis and Intracellular Calcium Mobilization of NK92 Cells. Influence of Dimethyl Fumarate and Monomethyl Fumarate. The FASEB Journal, 32: 667.2-667.2. https://doi.org/10.1096/fasebj.2018.32.1_supplement.667.2
  12. Maghazachi Azzam A., Editorial: Immunomodulatory Effects of Drugs for Treatment of Immune-Related Diseases, Frontiers in Immunology, 8, 2017, ISSN: 1664-3224, DOI: 10.3389/fimmu.2017.00969
  13. Guimei MM, Barqawi HJ, Dash NR, Maghazachi AA (2016) Sepsis- The Dilemma Continues. MOJ Immunol 4(3): 00125. DOI: 10.15406/moji.2016.04.00125
  14. Al-Jaderi, Z., & Maghazachi, A. A. (2015). Vitamin D3 and Monomethyl Fumarate Enhance Natural Killer Cell Lysis of Dendritic Cells and Ameliorate the Clinical Score in Mice Suffering from Experimental Autoimmune Encephalomyelitis. Toxins, 7(11), 4730-4744. https://doi.org/10.3390/toxins7114730
  15. Rolin J, Maghazachi AA. Chemokine receptors and inflammatory lipids. Implications for atherosclerosis. J. Leukoc. Biol. In press, April 2014.
  16. Rolin J, Maghazachi AA. Implications of chemokine receptors and inflammatory lipids in cancer. Immuno Targets and Therapy 3: 9-18, 2014.
  17. Al-Jaderi Z, Maghazachi AA. Effects of Vitamin D3, Calcipotriol and FTY720 on the expression of surface molecules and cytolytic activities of human natural killer cells and dendritic cells. Toxins 5: 1932-1947, 2013.
  18. Sand KL, Flatebo T, Andersen MB, Maghazachi AA. Effects of exercise on leukocytosis and blood hemostasis in 800 healthy young females and males. World J. Exp. Med. 2013 3(1): 11-20, 2013.
  19. Høglund R, Harbo HF, HolmøyT, Maghazachi AA. A one year follow-up study of natural killer and dendritic cells activities in multiple sclerosis patients receiving glatiramer acetate. PLoS One8(4): e62237, 2013.
  20. Maghazchi AA. On the role of natural killer cells in neurodegenerative diseases. Toxins 5: 363-375, 2013.
  21. Rolin J, Al-Jaderi Z, Maghazachi AA. Oxidized lipids and lysophosphatidylcholine induce the chemotaxis and intracellular calcium influx in natural killer cells. Immunobiology 218: 875-883, 2013.
  22. Maghazachi AA. Role of natural killer cells in multiple sclerosis. ISRN Immunology, 2012: article ID 795075, doi:10.5402/2012/795075, 2012.
  23. Troitskaya M, Baysa A, Vaage J, Sand KL, MaghazachiAA, Valen G. Interleukin-17 (IL-17) expression is reduced during acute myocardial infarction: role on chemokine receptor expression in monocytes and their in vitro chemotaxis towards chemokines. Toxins 4: 1427-1439, 2012.
  24. Pandya A, HøglundRA, HolmøyT, Harbo HF, Norgauer J, Maghazachi AA. Identification of human NK17/NK1 cells. PLoS One 6(10): e26780, 2011.
  25. Rolin J, Maghazachi AA. Effects of Lysophospholipids on Tumor Microenvironment. Cancer Microenvironment 4: 393-403, 2011.


Personal Profile

https://www.researchgate.net/profile/Azzam-Maghazachi-2

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