Biography

Dr. Joaquín M. Campos

Departamento de Química Farmacéuticay Orgánica

Facultad de Farmacia Universidad de Granada, Spain


Email: jmcampos@ugr.es


Qualifications

1981 Ph.D., University of Granada, Spain

1976 B.Sc., University of Granada, Spain


Publications (selected)


  1. da Silva, Á.C., Scholl, J.N., de Fraga Dias, A. et al. Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme. Purinergic Signalling 21, 39–50 (2025). https://doi.org/10.1007/s11302-023-09975-6
  2. Chayah, M., Luque-González, A., Gómez-Pérez, V., Salagre, D., Al-Shdaifat, A., Campos, J. M., … Agil, A. (2024). Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats. "Drug Design, Development and Therapy, 18, 1133–1141. https://doi.org/10.2147/DDDT.S450917
  3. Mali SN, dos Santos CBR, Campos Rosa J and Neves Cruz J (2024) Editorial: Investigation of the biological properties of natural products using experimental approaches and in silico methods. Front. Chem. 12:1406883. doi: 10.3389/fchem.2024.1406883
  4. Chayah M, Luque-González A, Gómez-Pérez V, Salagre D, Al-Shdaifat A, Campos JM, Conejo-García A, Agil A. Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats. Drug Des Devel Ther. 2024;18:1133-1141 https://doi.org/10.2147/DDDT.S450917
  5. Campos, J., Gleitze, S., Hidalgo, C., & Núñez, M. T. (2024). IP3R-Mediated Calcium Release Promotes Ferroptotic Death in SH-SY5Y Neuroblastoma Cells. Antioxidants, 13(2), 196. https://doi.org/10.3390/antiox13020196
  6. Da, Vitor & Lobato, Cleison & Silva, Luciane & Santos, Igor & Barros, Elcimar & Maciel, Alexandre & Ferreira, Elenilze & Santana, Kauê & Espejo-Román, José & Campos, Joaquín & Kimani, Njogu & Santos, Cleydson. (2024). Rational Approach to New Chemical Entities with Antiproliferative Activity on Ab1 Tyrosine Kinase Encoded by the BCR-ABL Gene: An Hierarchical Biochemoinformatics Analysis. Pharmaceuticals. 1491. 10.3390/ph17111491. 
  7. Barbosa, D. B., do Bomfim, M. R., de Oliveira, T. A., da Silva, A. M., Taranto, A. G., Cruz, J. N., de Carvalho, P. B., Campos, J. M., Santos, C. B. R., & Leite, F. H. A. (2023). Development of Potential Multi-Target Inhibitors for Human Cholinesterases and Beta-Secretase 1: A Computational Approach. Pharmaceuticals, 16(12), 1657. https://doi.org/10.3390/ph16121657
  8. Santos, C. B. R., Lobato, C. C., Ota, S. S. B., Silva, R. C., Bittencourt, R. C. V. S., Freitas, J. J. S., Ferreira, E. F. B., Ferreira, M. B., Silva, R. C., De Lima, A. B., Campos, J. M., Borges, R. S., & Bittencourt, J. A. H. M. (2023). Analgesic Activity of 5-Acetamido-2-Hydroxy Benzoic Acid Derivatives and an In-Vivo and In-Silico Analysis of Their Target Interactions. Pharmaceuticals, 16(11), 1584. https://doi.org/10.3390/ph16111584
  9. Oliveira, L. P. S., Lima, L. R., Silva, L. B., Cruz, J. N., Ramos, R. S., Lima, L. S., Cardoso, F. M. N., Silva, A. V., Rodrigues, D. P., Rodrigues, G. S., Proietti-Junior, A. A., dos Santos, G. B., Campos, J. M., & Santos, C. B. R. (2023). Hierarchical Virtual Screening of Potential New Antibiotics from Polyoxygenated Dibenzofurans against Staphylococcus aureus Strains. Pharmaceuticals, 16(10), 1430. https://doi.org/10.3390/ph16101430
  10. Bastos, R. S., de Lima, L. R., Neto, M. F. A., Maryam, Yousaf, N., Cruz, J. N., Campos, J. M., Kimani, N. M., Ramos, R. S., & Santos, C. B. R. (2023). Design and Identification of Inhibitors for the Spike-ACE2 Target of SARS-CoV-2. International Journal of Molecular Sciences, 24(10), 8814. https://doi.org/10.3390/ijms24108814
  11. Silva, L. B., Ferreira, E. F. B., Maryam, Espejo-Román, J. M., Costa, G. V., Cruz, J. V., Kimani, N. M., Costa, J. S., Bittencourt, J. A. H. M., Cruz, J. N., Campos, J. M., & Santos, C. B. R. (2023). Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach. Molecules, 28(3), 1035. https://doi.org/10.3390/molecules28031035
  12. de Almeida, R. B. M., Barbosa, D. B., do Bomfim, M. R., Amparo, J. A. O., Andrade, B. S., Costa, S. L., Campos, J. M., Cruz, J. N., Santos, C. B. R., Leite, F. H. A., & Botura, M. B. (2023). Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies. Pharmaceuticals, 16(1), 95. https://doi.org/10.3390/ph16010095
  13. Neto, M. F. A., Campos, J. M., Cerqueira, A. P. M., de Lima, L. R., Da Costa, G. V., Ramos, R. D. S., Junior, J. T. M., Santos, C. B. R., & Leite, F. H. A. (2022). Hierarchical Virtual Screening and Binding Free Energy Prediction of Potential Modulators of Aedes Aegypti Odorant-Binding Protein 1. Molecules, 27(20), 6777. https://doi.org/10.3390/molecules27206777
  14. Da Costa, G. V., Neto, M. F. A., Da Silva, A. K. P., De Sá, E. M. F., Cancela, L. C. F., Vega, J. S., Lobato, C. M., Zuliani, J. P., Espejo-Román, J. M., Campos, J. M., Leite, F. H. A., & Santos, C. B. R. (2022). Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach. International Journal of Molecular Sciences, 23(15), 8218. https://doi.org/10.3390/ijms23158218
  15. Silva, R. C., Freitas, H. F., Campos, J. M., Kimani, N. M., Silva, C. H. T. P., Borges, R. S., Pita, S. S. R., & Santos, C. B. R. (2021). Natural Products-Based Drug Design against SARS-CoV-2 Mpro 3CLpro. International Journal of Molecular Sciences, 22(21), 11739. https://doi.org/10.3390/ijms222111739
  16. Fraga Dias, A. de, Dallemole, D. R., Bruinsmann, F. A., Lopes Silva, L. F., Cruz-López, O., Conejo-García, A., … Figueiró, F. (2021). Development of Bozepinib-Loaded Nanocapsules for Nose-To-Brain Delivery: Preclinical Evaluation in Glioblastoma. Nanomedicine, 16(23), 2095–2115. https://doi.org/10.2217/nnm-2021-0164
  17. Santos, C. B. R., Santos, K. L. B., Cruz, J. N., Leite, F. H. A., Borges, R. S., Taft, C. A., … Silva, C. H. T. P. (2020). Molecular modeling approaches of selective adenosine receptor type 2A agonists as potential anti-inflammatory drugs. Journal of Biomolecular Structure and Dynamics, 39(9), 3115–3127. https://doi.org/10.1080/07391102.2020.1761878
  18. Lacal, J.C.; Zimmerman, T.; Campos, J.M. Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. Pharmaceutics 2021, 13, 788. [https://10.3390/pharmaceutics13060788]
  19. Lacal, J. C., Zimmerman, T., & Campos, J. M. (2021). Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases. Pharmaceutics, 13(6), 788. https://doi.org/10.3390/pharmaceutics13060788
  20. Macêdo, W.J.C. et al. (2021). High-Throughput-Based Virtual Screening via Molecular Docking for Oxidative Stress Mediated by ROS Enzyme. In: La Porta, F.A., Taft, C.A. (eds) Functional Properties of Advanced Engineering Materials and Biomolecules. Engineering Materials. Springer, Cham. https://doi.org/10.1007/978-3-030-62226-8_17


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