Prof. Richard Daniellou

University of Orleans, France

Email: richard.daniellou@univ-orleans.fr

Qualifications

2010 Habilitation, Universityof Rennes1, Chemistry

2003 Ph.D., University of Paris XI, Chemistry

2000 M.Sc., University of Paris XI, Organic Chemistry and Biochemistry

1998 B.Sc., University of Paris XI, Biochemistry

Publications (Selected)

1. Peltier, P.; Belá!ová, M.; Diani"ková, P.; Zhou, R.; Zheng, R.B.; Pearcey, J.A.; Joe, M.; Brennan, P.J.; Nugier-Chauvin, C.; Ferrières, F.; Lowary, T.L.; Daniellou, R.; Miku"ová K. Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis. Chem. Biol. 2010, 17, 1356-1366.
2. Bellomo, A.; Daniellou, R.; Plusquellec, D. Allylation of cyclohexanones in aqueous media and influence of facial amphiphilic fructopyranosides. Tetrahedron Lett. 2010, 51, 2083-2085.
3. Sylla, B.; Descroix, K.; Pain, C.; Gervaise, C.; Jamois, F.; Yvin, J.-C.; Legentil, L.; Nugier-Chauvin, C.; Daniellou, R.; Ferrières, V. Double diastereoselection explains limitations in synthesizing mannose-containing b-(1-3)-glucans. Carbohydr. Res. 2010, 345, 1366-1370.
4. Chlubnova, I.; Filipp, D.; Spiwok, V.; Dvo#áková, H.; Daniellou, R.; Nugier-Chauvin, C.; Králová, B.; Ferrières, V. Enzymatic synthesis of oligo-D-galactofuranosides and Larabinofuranosides: from molecular dynamics to immunological assays. Org. Biomol. Chem. 2010, 8, 2092-2102.
5. Dureau, R.; Robert-Gangneux, F.; Gangneux, J.-P. ; Nugier-Chauvin, C. ; Legentil, L.; Daniellou, R. ; Ferrières, V. Synthetic UDP-furanoses inhibit the growth of the parasite Leishmania. Carbohydr. Res. 2010, 345, 1299-1305.
6. Collen, P.N.; Lemoine, M.; Daniellou, R.; Guégan, J.P.; Paoletti, S.; Helbert, W. Enzymatic degradation of k-carrageenan in aqueous solution. Biomacromol. 2009, 10, 1757-1767.
7. Gervaise, C.; Daniellou, R.; Nugier-Chauvin, C.; Ferrières, V. Influencing the regioselectivity of lipase-catalyzed hydrolysis with [bmim]PF6. Tetrahedron Lett. 2009, 50, 2083-2085.
8. Eppe, G.; Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrières, V.; Vincent, S.P. Probing the UDP-galactopyranose mutase binding pocket: a dramatic effect on substitution of the 6-position of UDP-galactofuranose. Bioorg. Med. Chem. Lett. 2009, 19, 814-816.
9. Peltier, P.; Guégan, J.P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrières, V. Stereoselective chemoenzymatic synthesis of UDP-1,2-cis-furanoses from !,"-furanosyl 1-phosphates. Eur. J. Org. Chem. 2008, 5988-5994.
10. Jakeman, D.L.; Young, J.L.; Huestis, M.P.; Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrières V. Engineering ribonucleoside triphosphate specificity in a thymidylyltransferase. Biochemistry 2008, 47, 8719-8725.
11. Peltier, P.; Euzen, R.; Daniellou, R.; Nugier-Chauvin, C.; Ferrières, V. Recent knowledge and innovations related to hexofuranosides. Structure, synthesis and applications. Carbohydr. Res. (revue) 2008, 343, 1897-1923.
12. Timmons, S. C.; Hui, J. P. M.; Pearson, J. L.; Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Soo, E. C.; Syvitski, R. T.; Ferrieres, V.; Jakeman, D. L., Enzyme-Catalyzed Synthesis of Furanosyl Nucleotides. Org. Lett. 2008, 10, 161-163.
13. Peltier, P.; Daniellou, R.; Roisnel, T.; Nugier-Chauvin, C.; Ferrieres, V., 4-Nitrophenyl !-Lrhamnopyranoside hemihydrate. Acta Crystallogr. Sect. E 2008, E64, o379.
14. Peltier, P.; Daniellou, R.; Nugier-Chauvin, C.; Ferrieres, V., Versatile Synthesis of Rare Nucleotide Furanoses. Org. Lett. 2007, 9, 5227-5230.
15. Daniellou, R.; Zheng, H.; Langill, D. M.; Sanders, D. A. R.; Palmer, D. R. J., Probing the Promiscuous Active Site of myo-Inositol Dehydrogenase Using Synthetic Substrates, Homology Modeling, and Active Site Modification. Biochemistry 2007, 46, 7469-7477.
16. Gervaise, C.; Daniellou, R.; Roisnel, T.; Nugier-Chauvin, C.; Ferrieres, V., Benzyl 4,6-di-Oacetyl-2-O-benzoyl-b-D-glucopyranoside. Acta Crystallogr. Sect. E 2007, E63, o2286-o2288.
17. Lopez, G.; Daniellou, R.; O'Donohue, M.; Ferrières, V.; Nugier-Chauvin, C., Thioimidoyl furanosides as first inhibitors of the !-arabinofuranosidase AbfD3. Bioorg. Med. Chem. Lett. 2007, 17, 434-438.
18. Daniellou, R.; Zheng, H.; Palmer, D. R. J., Kinetics of the reaction catalyzed by inositol dehydrogenase from Bacillus subtilis and inhibition by fluorinated substrate analogs. Can. J. Chem. 2006, 84, 522-527.
19. Daniellou, R.; Quail, J. W.; Palmer, D. R. J., 4/6-O-(p-Tolylsulfonyl)-myo-inositol. Acta Crystallogr. Sect. E 2006, E62, o4880-o4881.
20. Daniellou, R.; Palmer, D. R. J., Appel-Lee synthesis of glycosyl inositols, substrates for inositol dehydrogenase from Bacillus subtilis. Carbohydr. Res. 2006, 341, 2145-2150.
21. Daniellou, R.; Phenix, C. P.; Tam, P. H.; Laliberte, M. C.; Palmer, D. R. J., Stereoselective oxidation of protected inositol derivatives catalyzed by inositol dehydrogenase from Bacillus subtilis. Org. Biomol. Chem. 2005, 3, 401-403.
22. Daniellou, R.; Le Narvor, C., Synthesis of GDP-fucose on a soluble support: A donor substrate for the fucosyltransferases. Adv. Synth. Catal. 2005, 347, 1863-1868.
23. Renaudie, L.; Daniellou, R.; Augé, C.; Le Narvor, C., Enzymatic supported synthesis of lacto-N-neotetraose using dendrimeric polyethylene glycol. Carbohydr. Res. 2004, 339, 693-698.