Biography

Prof. Hironobu Ihn

Kumamoto University, Japan

Email: ihn-der@kumamoto-u.ac.jp


Qualifications

1998 Ph.D., University of Tokyo, Japan

1990 M.D., University of Tokyo, Japan


Publications (Selected)

  1. Nakahara S, Fukushima S, Yamashita J, Kubo Y, Tokuzumi A, Miyashita A, Harada M, Nakamura K, Jinnin M, Ihn H. AT-rich interaction domain-containing protein 3B is a new tumor marker for melanoma. Acta Derm Venereol, 96: 112-114, 2017.
  2. Hamaguchi Y, Sumida T, Kawaguchi Y, Ihn H, Tanaka S, Asano Y, Motegi S, Kuwana M, Endo H, Takehara K. Safety and tolerability of bosentan for digital ulcers in Japanese patients with systemic sclerosis: prospective, multicenter, open-labele study. J Dermatol, 44: 13-17, 2017.
  3. Nakayama W, Jinnin M, Tomizawa Y, Nakamura K, Kudo H, Inoue K, Makino K, Honda N, Kajihara I, Fukushima S, Ihn H. Dysregulated Interleukin-23 signalling contributes to the increased collagen production in scleroderma fibroblasts via balancing microRNA expression. Rheumatology, 56: 145-155, 2017.
  4. Noguchi H, Hiruma M, Matsumoto T, Kano R, Ihn H. Ungual hyalohyphomycosis caused by Fusarium proliferatum in an immunocompetent patient. J Dermatol, 44: 88-90, 2017.
  5. Amagai M, Ikeda S, Hashimoto T, Mizuashi M, Fujisawa A, Ihn H, Matsuzaki Y, Ohtsuka M, Fujiwara H, Furuta J, Tago O, Yamagami J, Tanikawa A, Uhara H, Morita A, Nakanishi G, Tani M, Aoyama Y, Makino E, Muto M, Manabe M, Konno T, Murata S, Izaki S, Watanabe H, Yamaguchi Y, Matsukura S, Seishima M, Habe K, Yoshida Y, Kaneko S, Shindo H, Nakajima K, Kanekura T, Takahashi K, Kitajima Y, Hashimoto K. A randomized double-blind trial of intranenous immunoglobulin for bullous pemphigoid. J Dermatol Sci, 85: 77-84, 2017.
  6. Harada M, Jinnin M, Wang Z, Hirano A, Tomizawa Y, Kira T, Igata T, Masuguchi S, Fukushima S, Ihn H. The expression of miR-124 increases in aged skin to cause cell senecense and it decreases in squamous cell carcinoma. Biosci Trends, 10: 454-459, 2017.
  7. Wang Z, Jinnin M, Harada M, Kudo H, Inoue K, Nakayama W, Honda N, Makino K, Kajihara I, Fukushima S, Ihn H. Diagnosis of nail psoriasis: evaluation of nail-derived microRNAs as potential novel biomarkers. Eur J Dermatol, 27: 20-27, 2017.
  8. Maeda S, Kajihara I, Ogata A, Johno T, Jinnin M, Ihn H. Bromoderma in a pituitary adenoma patient treated with bromocriptine. J Dermatol, 44: e95-e96, 2017.
  9. Egashira S, Kajihara I, Kanemaru H, Uemura-Kiyohara M, Yamada-Kanazawa S, Nakahara S, Nagamoto E, Fukushima S, Jinnin M, Inoue Y, Ihn H. Achieved good response of S-1 and docetaxel combination chemotherapy in two patients with metastatic extramammary Paget’s disease. J Dermatol, 44: e103-e104, 2017.
  10. Saeki H, Nakagawa H, Nakajo K, Ishii T, Morisaki Y, Aoki T, Cameron GS, Osuntokun OO, Akasaka T, Asano Y, Etoh T, Fujita Y, Hashimoto T, higashiyama M, Igarashi A, Ihn H, Iwatsuki K, Kabashima K, Kawada A, Kawashima M, Nakamura K, Okubo Y, Okuyama R, Ozawa A, Sayama K, Seishima M, Shiohara T, Takahara M, Takahashi H, Takehara K, Tanase K, Tani M, Umezawa Y, watanabe H, Yamanaka K. Efficacy and safety of ixekizumab treatment for Japanese patients with moderate to severe plaque psoriasis, erythrodermic psoriasis and generalized pustular psoriasis: Results from a 52-week, open-label, phase 3 study (UNCOVER-J). J Dermatol, 44: 355-362, 2017.
  11. Noguchi H, Hiruma M, Matsumoto T, Yaguchi T, Sano A, Mitsui N, Watanabe S, Ihn H. Subcutaneous cystic phaeohyphomycosis due to Pleurostomophora richardiae. J Dermatol, 44: e62-e63, 2017.
  12. Yamazaki N, Takenouchi N, Fujimoto M, Ihn H, Uchi H, Inozume T, Kiyohara Y, Uhara H, Nakagawa K, Furukawa H, Wada H, Noguchi K, Shimamoto T, Yokota K. Phase 1b study of pembrolizumab (MK-3475; anti-PD-1 monoclonal antibody) in Japanese patients with advanced melanoma (KEYNOTE-041). Cancer Chemother Pharmacol, 79: 651-660, 2017.
  13. Torii H, Nakano M, Yano T, Kadono K, Nakagawa H, Fujita Y, Horie K, Ito M, Iitani M, Ito K, Kaneko T, Akasaka T, Ohtsuki M, Yasuda M, Abe M, Tanida Y, Terui T, Arai S, Nakano T, Etoh T, Asano Y, Umezawa Y, Saeki H, Adachi M, Seishima M, Tokura Y, Morita A, Yamanaka K, Tani M, Tanimura H, Yamazaki F, Nishigori C, Kaneko S, Muto M, Nakamura M, Hino R, Nakayama J, Nakano T, Utani A, Sato T, Ihn H. Efficacy and safety of dose escalation of infliximab therapy in Japanese patients with psoriasis: Results of the SPREAD study. J Dermatol, 44: 552-559, 2017.
  14. Terao C, Kawaguchi T, Dieude P, Varga J, Kuwana M, Hudson M, Kawaguchi Y, Matucci M, Ohmura K, Riemekasten G, Kawasaki A, Airo P, Horita T, Oka A, Hachulla E, Yoshifuji H, Japanese Scleroderma Genetic Consortium, Caramaschi P, Hunzelman N, Baron M, Hassouns P, Raychaudhuri S, Liao K, Gregersen P, Torii T, Tsuchiya N, Takehara K, Sato S, Ihn H, Riccieri V, Melchers I, Valentini G, Cauvet A, Martinez M, Mimori T, Matsuda F, Allanore Y. Trans-ethnic meta-analysis of genome-wide association study identifies GSDMA and PRDM1 as susceptibility genes to systemic sclerosis. Ann Rheum Dis, 76: 1150-1158, 2017.
  15. Noguchi H, Hiruma M, Matsumoto T, Kano R, Tanaka M, Yaguchi T, Sonoda K, Ihn H. Fungal melanonychia: Ungual phaeohyphomycosis caused by Botryospheria dothidea. Acta Derm Venereol,97: 765-766, 2017.
  16. Tanigawa H, Miyata K, Tian Z, Aoi J, Kadomatsu T, Fukushima S, Ogata A, Takeda N, Zhao J, Zhu S, Terada K, Endo M, Norinaga J, Sugizaki T, Sato M, Morioka MS, Manabe I, Mashimo Y, Hata A, Takemori Y, Yamamoto K, Murakami M, Araki K, Jinnin M, Ihn H, Oike Y. Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis. Sci Rep, 6: 34690, 2016.
  17. Noguchi H, Hirum M, Maruo K, Jono M, Miyata K, Tanaka H, Tanabe K, Miyazaki Y, Ihn H. Localized cutaneous cryptococcosis: Summary of reported cases in Japan. Med Mycol J 57: E35-E39, 2016.
  18. Yamada S, Jinnin M, Kajihara I, Nakashima T, Aoi J, Harada M, Igata T, Masuguchi S, Fukushima S, Ihn H. Cytokine expression profiles in the sera of cutaneous squamous cell carcinoma patients. Drug Discov Ther, 10: 172-176, 2016.
  19. Kimura T, Fukushima S, Miyashita A, Aoi J, Jinnin M, Kosaka T, Ando Y, Matsukawa M, Inoue H, Kiyotani K, Park J-H, Nakamura Y, Ihn H. Myasthenic crisis and polymyositis induced by one dose of nivolumab. Cancer Sci, 107: 1055-1058, 2016.
  20. Inoue M, Jinnin M, Wang Z, Nakamura K, Inoue K, Ichihara A, Moriya C, Sakai K, Fukushima S, Ihn H. microRNA level is raised in the hair shafts of patients with dermatomyositis in comparison with normal subjects and patients wuth scleroderma. Int J Dermatol, 55: 786-790, 2016.
  21. Nakamura K, Jinnin M, Kudo H, Inoue K, Nakayama W, Honda N, Kajihara I, Masuguchi S, Fukushima S, Ihn H. The role of PSMB9 up-regulation by interferon signature in the pathophysiology of cutaneous lesions of dermatomyositis and lupus erythematosus. Br J Dermatol, 174: 1030-1041, 2016.
  22. Noguchi H, Hiruma M, Miyashita A, Makino K, Miyata K, Ihn H. A case of fingernail onychomycosis due to Aspergillus flavus. Medical Mycol J, 57: E21-E25, 2016.
  23. Uchihara T, Imamura Y, Iwagami S, Kajihara I, Kanemaru H, Karashima R, Ida S, Ishimoto T, Baba Y, Sakamoto Y, Miyamoto Y, Yoshida N, Watanabe M, Iyama K, Ihn H, Baba H. Small bowel perforation due to indistinguishable metasatsis of angiosarcoma: case report and brief literature review. Surg Case Rep 2: 42, 2016.
  24. Koga A, Kajihara I, Yamada S, Makino K, Ichihara A, Aoi J, Makino T, Fukushima S, Jinnin M, Ihn H. Enhanced CCR9 expression levels in psoriatic skin are associated with poor clinical outcome to infliximab treatment. J Dermatol, 43: 522-525, 2016.
  25. Yoshino Y, Ohtsuka M, Kawaguchi M, Sakai K, Hashimoto A, Hayashi M, Madokoro N, Asano Y, Abe M, Ishii T, Isei T, Ito T, Inoue Y, Imafuku S, Irisawa R, Ohtsuka M, Ogawa F, Kadono T, Kawakami T, Kukino R, Kono T, Kodera M, Takahara M, Tanioka M, Nakanishi T, Nakamura Y, Hasegawa M, Fujimoto M, Fujiwara H, Maekawa T, Matsuo K, Yamasaki O, Le Pavoux A, Tachibana T, Ihn H. The woud/ burn guidelines – 6: Guidelines for management of burns. J Dermatol, 43: 989-1010, 2016.


Profile Details

https://www.researchgate.net/profile/Hironobu-Ihn/5

https://clinicalcasereportsjournal.com/profile/100064/hironobu-ihn

https://sciforschenonline.org/journals/clinical-research/hironobu-ihn.php


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