Dr. Zhong-Ping Feng
University of Toronto, Canada
Email: zp.feng@utoronto.ca
Qualifications
2008-Present Associate
Professor, University of Toronto, Canada
2003-2008 Assistant Professor, University of Toronto, Canada
1999-2002 Research Scientist,
NeuroMed Technologies Inc. Vancouver/Calgary, Canada
Publications (Selected)
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Guo C., Senzel A., Li, K., Feng Z.-P.*
(2010) De novo protein synthesis of syntaxin-1 and dynamin-1 in long-term
memory formation requires CREB1 gene transcription in Lymnaea stagnalis. Behav.
Genet. Epub ahead of print
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Pajouhesh H., Feng Z.-P., Zhang L., Ding
Y., Zhang L., Pajouhesh H., Belardetti F., Tringham E., Simonson E., Vanderah
T.W., Porreca F., Zamponi G.W., Mitscher L.A., Snutch T.P. (2010)
Structure-activity relationships of diphenylpiperazine N-type calcium channel
inhibitors. Bioorganic Med. Chem. Lett. 20(4):1378-83.
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Feng Z.-P.*, Zhang Z.*, van Kesteren
R.E., Straub V., van Nierop P., Jin K., Nejatbakhsh N., Goldberg J.I., Spencer
G., Yeoman M., Wildering W., Coorssen J.R., Croll R.P., Buck L., Syed N.I.*,
Smit A.B.* (2009) Transcriptome analysis of the central nervous system of the
mollusk Lymnaea stagnalis. BMC Genomics. 10(1):451
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Zamponi GW, Feng Z.-P., Zhang L,
Pajouhesh H, Ding Y., Belardetti F., Pajouhesh H., Dolphin D., Mitscher L.A.,
Snutch T.P. (2009) Scaffold-based design and synthesis of potent N-type calcium
channel blockers. Bioorganic Med. Chem. Lett. 19(22):6467-72.
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Silverman-Gavrila L.B., Lu T.Z.,
Prashad, P.C., Nejabakhsh N., Charlton M.P., and Feng Z.-P.* (2009) Neural
phosphoproteomics of a chronic hypoxia model - Lymnaea stagnalis. Neurosci.
161(2):632-34
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Hui K., Kwok T.C.Y., Kosteleski W.,
Leen J., Roy P.C.*, and Feng Z.-P.* (2009) Differential sensitivities of CaV1.2
IIS5-S6 mutants to 1,4-dihydropyridine (DHP) analogous. Euro. J. Pharmacol.
602(2-3):255-61
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Betourne A., Bertholet A.M., Labroue
E, Halley H., Sun H.S., Lorsignol A., Feng Z.-P., French R.J., Penicaud L.,
Lassalle J.-M., and Frances B. (2009) Involvement of hippocampal CA3 KATp
Kir6.2/SUR1 channels in contextual memory. Neuropharmacol. 56, 615-625
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Sun H.S., French R.J., and Feng Z.-P.*
(2009) A simple and reliable technique for identifying both viable and damaged
neurons in single brain slices exposed to oxygen and glucose deprivation. Acta
Histochem. Feb 7
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Kwok T.C.Y.#, Hui K.#, Kosteleski W.,
Ricker N., Selman G., Feng Z.-P.*, and Roy P.C.* (2008) A screen for
dihydropyridine (DHP)-resistant worms reveals a mechanism for DHPblockage of
mammalian calcium channels. PloS Genetics 4(5):e1000067.
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Fei G.H., and Feng Z.-P.* (2008)
Oxygen supplement rescues chronic hypoxia induced neural suppression. Neurosci.
153(1):318-28.
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Hui K., and Feng Z.-P.* (2008)
Differences in growth cone and somata calcium current properties revealed by
NCS-1. Euro J Neurosci. 27(3):631-43
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Kim I., Mai W., Hui K., Moeckel G., Li
C., Liang D., Huang S., Zuo A., Cho S., Li Q., Zhao P., Ma J., Fu Y., Che X.,
Guo C., Yu X., George A.L. Jr., Coffey R.J., Wu D., Feng Z.-P., and Wu G.
(2008) Pkhd1 mediates Pkd2 expression and functions in the same cystogenic
pathway. J. Am. Soc. Nephrol. 19(3):455-68
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Wu J., Sun Z., Sun H.S., Wu J., Weisel
R.D., Keating A., Feng Z.-P., and Li R.-K. (2008) Intravenous implantation of
bone marrow stem cells decreases neuron damage and improves neural function.
Cell Transplant. 16(10):993-1005
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Fei G., Guo C., Sun S.H., and Feng
Z.-P.* (2008) HSP70 reduces chronic hypoxia-induced neural suppression via
direct interaction with syntaxin. Adv Exp Med Biol. 605:35-40.
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Hui K., Fei G., Saab B., Sue J., Roder
J., and Feng Z.-P.* (2007) NCS-1 selectively regulates growth cone voltage-dependent
Ca2+ channel and is involved in neurite branching in Lymnaea stagnalis neurons.
Development. 134:4479-89.
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Sun H.S., Hui K., Lee D.W.K., and Feng
Z.-P.* (2007) Zn sensitivity of high- and low-voltage activated calcium
channels. Biophys J. 93(4):1175-83
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Gardzinski P., Lee D.W.K., Fei G.H.,
Hui K., Huang G., Sun H.-S., and Feng Z.-P.* (2007) Mechanisms underlying
synaptic target cell - induced synaptotagmin clustering during synapse
formation between identified Lymnaea neurons. J Physiol. (Lond.) 581:75-90.
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Fei G., Guo C., Sun S.H., and Feng
Z.-P.* (2007) Chronic hypoxia stress induced differential modulation of HSP70
and presynaptic proteins. J Neurochem. 100:50-61.
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Sun H.S., Feng Z.-P., Barber P.A.,
Alastair M., and French R.J. (2007) Kir6.2-contraining KATP channels protect
cortical neurons from ischemic/anoxic injury in vitro and in vivo. Neuroscience
144(4):1509-15. (SHS: Visiting Ph.D. student in my lab)