Prof. Ping Yang
Mayo Clinic, USA

Email: yang.ping@mayo.edu

Qualifications
1992  Post-Doctoral Fellowship, Fox-Chase Cancer Center
1990  Doctor of Philosophy, Johns Hopkins University
1985  Master of Public Health, Johns Hopkins University
1983  Bachelor of Medicine, Beijing Medical College

Publications (Selected)

1. Peng, Y., Li, D., Wampfler, J. A., Luo, Y. H., Kumar, A. V., Gu, Z., Kosuru, N., Yu, N. Y., Wang, Z., Leventakos, K., Ernani, V., & Yang, P. (2025). Targeted therapy‑associated cardiotoxicity in patients with stage‑IV lung cancer with or without cardiac comorbidities. Oncology reports, 53(2), 25. https://doi.org/10.3892/or.2024.8858
2. Zuo, X., Kumar, A., Shen, S., Li, J., Cong, G., Jin, E., Chen, Q., Warner, J. L., Yang, P., & Xu, H. (2024). Extracting Systemic Anticancer Therapy and Response Information From Clinical Notes Following the RECIST Definition. JCO clinical cancer informatics, 8, e2300166. https://doi.org/10.1200/CCI.23.00166
3. Rajaganapathy, S., Chowdhury, S., Buchner, V., He, Z., Jiang, X., Yang, P., Cerhan, J. R., & Zong, N. (2024). Synoptic Reporting by Summarizing Cancer Pathology Reports using Large Language Models. medRxiv : the preprint server for health sciences, 2024.04.26.24306452. https://doi.org/10.1101/2024.04.26.24306452
4. Peng, Y., Ernani, V., Liu, D., Guo, Q., Hopps, M., Cappelleri, J. C., Gupta, R., de Andrade, M., Chen, J., Yi, E. S., & Yang, P. (2024). Lung adenocarcinoma patients with ROS1-rearranged tumors by sex and smoking intensity. Heliyon, 10(7), e28285. https://doi.org/10.1016/j.heliyon.2024.e28285
5. Dos Santos, P. A. R., Li, Y., Ernani, V., D'Cunha, J., Aubry, M. C., & Yang, P. (2023). Clinical outcomes of stage-IV non-small-cell lung cancer in young patients and the impact of tumor markers. Cancer treatment and research communications, 36, 100723. https://doi.org/10.1016/j.ctarc.2023.100723
6. Ernani, V., Appiah, A. K., Rodriguez, D., Kusne, Y., Beamer, S. E., Ravanbakhsh, S., Jaroszewski, D., Reck Dos Santos, P., Sio, T. T., Yu, N., Yang, P., Schild, S., & D'Cunha, J. (2023). Lobar versus sublobar resection for atypical lung carcinoid: An analysis from the National Cancer Database. Cancer, 129(6), 860–866. https://doi.org/10.1002/cncr.34614
7. He, Y., Wei, C., Sun, Z., Cunningham, J. M., Wang, L., Wei, Z., & Yang, P. (2022). Genome-wide methylation profiling reveals differentially methylated genes in blood DNA of small-cell lung cancer patients. Precision clinical medicine, 5(3), pbac017. https://doi.org/10.1093/pcmedi/pbac017
8. Kehl, K. L., Zahrieh, D., Yang, P., Hillman, S. L., Tan, A. D., Sands, J. M., Oxnard, G. R., Gillaspie, E. A., Wigle, D., Malik, S., Stinchcombe, T. E., Ramalingam, S. S., Kelly, K., Govindan, R., Mandrekar, S. J., Osarogiagbon, R. U., & Kozono, D. (2022). Rates of Guideline-Concordant Surgery and Adjuvant Chemotherapy Among Patients With Early-Stage Lung Cancer in the US ALCHEMIST Study (Alliance A151216). JAMA oncology, 8(5), 717–728. https://doi.org/10.1001/jamaoncol.2022.0039
9. Dai, J., He, Y., Maneenil, K., Liu, H., Liu, M., Guo, Q., Bennett, A. C., Stoddard, S. M., Wampfler, J. A., Jiang, G., & Yang, P. (2021). Timing of chronic obstructive pulmonary disease diagnosis in lung cancer prognosis: a clinical and genomic-based study. Translational lung cancer research, 10(3), 1209–1220. https://doi.org/10.21037/tlcr-20-1017
10. Musolf, A. M., Simpson, C. L., Moiz, B. A., Pikielny, C. W., Middlebrooks, C. D., Mandal, D., de Andrade, M., Cole, M. D., Gaba, C., Yang, P., You, M., Li, Y., Kupert, E. Y., Anderson, M. W., Schwartz, A. G., Pinney, S. M., Amos, C. I., & Bailey-Wilson, J. E. (2021). Genetic Variation and Recurrent Haplotypes on Chromosome 6q23-25 Risk Locus in Familial Lung Cancer. Cancer research, 81(12), 3162–3173. https://doi.org/10.1158/0008-5472.CAN-20-3196
11. Li, X., Sigworth, E. A., Wu, A. H., Behrens, J., Etemad, S. A., Nagpal, S., Go, R. S., Wuichet, K., Chen, E. J., Rubinstein, S. M., Venepalli, N. K., Tillman, B. F., Cowan, A. J., Schoen, M. W., Malty, A., Greer, J. P., Fernandes, H. D., Seifter, A., Chen, Q., Chowdhery, R. A., … Warner, J. L. (2020). Seven decades of chemotherapy clinical trials: a pan-cancer social network analysis. Scientific reports, 10(1), 17536. https://doi.org/10.1038/s41598-020-73466-6
12. Wang, L., Wampfler, J., Dispenzieri, A., Xu, H., Yang, P., & Liu, H. (2020). Achievability to Extract Specific Date Information for Cancer Research. AMIA ... Annual Symposium proceedings. AMIA Symposium, 2019, 893–902.
13. Murphy, S. J., Harris, F. R., Kosari, F., Barreto Siqueira Parrilha Terra, S., Nasir, A., Johnson, S. H., Serla, V., Smadbeck, J. B., Halling, G. C., Karagouga, G., Sukov, W. R., Leventakos, K., Yang, P., Peikert, T., Mansfield, A. S., Wigle, D. A., Yi, E. S., Kipp, B. R., Vasmatzis, G., & Aubry, M. C. (2019). Using Genomics to Differentiate Multiple Primaries From Metastatic Lung Cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 14(9), 1567–1582. https://doi.org/10.1016/j.jtho.2019.05.008
14. Cathcart-Rake, E., Smith, D., Zahrieh, D., Jatoi, A., Yang, P., & Loprinzi, C. L. (2018). Nasal vestibulitis: an under-recognized and under-treated side effect of cancer treatment?. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 26(11), 3909–3914. https://doi.org/10.1007/s00520-018-4261-7
15. Klee EW, Erdogan S, Tillmans L, Kosari F, Sun Z, Wigle DA, Yang P, Aubry MC, Vasmatzis G. Impact of sample acquisition and linear amplication on gene expression profiling of lung adenocarcinoma: Laser capture micro-dissection cell-sampling versus bulk tissue-sampling. BMC Medical Genomics. 2009 Mar 9;2:13. PMCID: PMC 2667433.
16. You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW. Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.
17. Gegg-Harrison T, Zhang M, Meng N, Sun Z, Yang P. Porting a cancer treatment prediction to a mobile device. IEEE Engineering in Medicine and Biology Society. 2009;September 2-6:6218-9221; PMCID: PMC2797080.
18. Zhang M, Zhang W, Sicotte H, Yang P. A new validity measure for a correlation-based fuzzy C-means clustering algorithm. IEEE Engineering in Medicine and Biology Society. 2009;September 2-6:3865-3868; PMCID: PMC2818127.
19. Yang P. Increased risk for lung cancer found in alpha-1antitrypsin deficiency carriers. EGRP Research Highlights - Epidemiology and Genetics Research Program. Bethesda, National Cancer Institute 2009;(Spring):7.
20. Chen J, Jiang R, Garces YI, Jatoi A, Stoddard SM, Sun Z, Marks RS, Liu Y, Yang P. Prognostic factors for limited -stage small cell lung cancer: A study of 284 patients.Lung Cancer 2010;67(2):221-226; PMCID: PMC2815153.
21. Yang P, Mandrekar SJ, Hillman SH, Allen Ziegler KL, Sun Z, Wampfler JA, Cunningham JM, Sloan JA, Adjei AA, Perez E, Jett JR. Evaluation of glutathione metabolic genes on outcomes in advanced non-small cell lung cancer patients after initial treatment with platinum-based chemotherapy: An NCCTG-97-24-51 based study.Journal of Thoracic Oncology 2009;4(4):479-485. PMCID: (in process).
22. Boland JM, Erdogan S, Vasmatzis G, Yang P, Tillmans LS, Erickson Johnson MR, Wang X, Peterson LM, Halling KC, Oliveira AM, Aubry MC, Yi ES. Anaplastic lymphoma kinase (ALK) immunoreactivity correlates with ALK gene rearrangement and transcriptional upregulation in non-small cell lung carcinomas. Human Pathology 2009; 40(8):1152-8. PMCID: (in process).
23. Aubry MC, Savci-Heijink CD, Kosari F, Caron BL, Sun Z, Yang P, Vasmatzis G. The role of desmoglein-3 in the diagnosis of squamous cell carcinoma of the lung. American Journal of Pathology 2009; 174(5):1629-37. PMCID: PMC2671252.
24. Landi MT, Dracheva T, Rotunno M, Figueroa JD, Liu H, Dasgupta A, Mann FE, Fukuoka J, Hames M, Bergen AW, Murphy SE, Yang P, Pesatori AC, Consonni D, Bertazzi PA, Wacholder S, Shih JH, Caporaso NE, Jen J. Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival. PLoS One 2008; 3(2):e1651.
25. Ahmed AU, Schmidt RL, Park CH, Reed NR, Hesse SE, Thomas CF, Molina JR, Deschamps C, Yang P, Aubry MC, Tang AH. Effect of disrupting seven-in-absentia homolog 2 function on lung cancer cell growth. JNCI 2008; 100(22):1606-1629.
26. Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M. Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. JNCI 2008; 100(18):1326-1330. PMCID: PMC2538550.
27. Macarenco RS, Uphoff TS, Flynn Gilmer H, Jenkins RB, Thibodeau SN, Lewis JE, Molina J, Yang P, Aubry MC. Salivary gland-type lung carcinomas: an EGFR immunohistochemical, molecular genetic, and mutational analysis study. Modern Pathol 2008; 21:1168-1175.
28. Molina JR, Yang P, Cassivi SD, Schild SE, Adjei AA. Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship.Mayo Clin Proc 2008; 83(5):584-594.
29. Sun Z, Wigle DA, and Yang P. Non-overlapping and non-cell type specific gene expressionsignatures predict lung cancer survival. J Clin Oncol 2008; 26(6):877-883.
30. Clark MM, Novotny PJ, Patten CA, Rausch SM, Garces YI, Jatoi A, Sloan JA, Yang P. Motivational Readiness for Physical Activity and Quality of Life in Long Term Lung Cancer Survivors.Lung Cancer 2008;61:117-122.
31. Hong KM, Yang SH, Chowdhuri SR, Player A, Hames M, Fukuoka J, Meerzaman D,Dracheva T, Sun Z, Yang P, Jen J. Inactivation of LLC1 gene in nonsmall cell lung cancer. Int J Cancer 2007;120(11):2353-58.
32. Yang P, Sun Z, Krowka, MJ, Aubry MC, Bamlet WR, Wampfler JA, Thibodeau SN,Katzmann JA, Allen MS, Midthun DE, Marks RS, de Andrade M. Alpha-1 AntitrypsinDeficiency Carriers, Tobacco Smoke, Chronic Obstructive Pulmonary Disease, and LungCancer Risk. Archives of Internal Medicine 2008;168(10):1097-1103.
33. Jatoi A, Novotny P, Cassivi S, Clark MM, Midthun D, Patten CA, Sloan J, Yang P. DoesMarital Status Impact Survival and Quality of Life in Patients with Non-Small Cell LungCancer? Observations from the Mayo Clinic Lung Cancer Cohort. The Oncologist2007;12(12):1456-1463.
34. Malmer B, Adatto P, Armstrong G, Barnholtz-Sloan J, Berstein JL, Claus E, Davis F,Houlston R, Il’yasova D, Jenkins R, Johnsen C, Lai R, Lau C, McCarthy B, Nielsen H, OlsonSH, Sadetzki S, Shete S, Wiklund F, Wrensch M, Yang P, Bondy M. GLIOGENE - aninternational consortium to understand familial glioma. Cancer Epidemiol Biomarkers Prev2007;16(9):1730-1734.
35. Taioli E, Benhamou S, Bouchardy C, Cascorbi I, Cajas-Salazar N, Dally H, Fong KM,Larsen JE, Le Marchand L, London SJ, Risch A, Spitz MR, Stucker I,Weinshenker B, Wu X,Yang P. Myeloperoxidase g-463 polymorphism and lung cancer: A HuGE geneticsusceptibility to environmental carcinogens pooled analysis. Genetics in Medicine2007;9:67-73.
36. Molina JR, Aubry MC, Lewis JE, Wampfler JA, Williams BA, Midthun DE, Yang P,Cassivi SD. Primary salivary-type lung cancer. Spectrum of clinical presentation,histopathology, and prognostic factors. Cancer 2007;110:2253-2259.
37. Aubry MC, Heinrich MC, Molina J, Lewis JE, Yang P, Cassivi SD, Corless CL. Primaryadenoid cystic carcinoma of the lung: Absence of KIT mutations. Cancer 2007;110:2507-2510.
38. Savic-Heijink CD, Kosari F, Vasmatzis G, Sun Z, Yang P, Aubry MC. The role ofdesmoglein-3 in the diagnosis of squamous cell carcinoma of the lung. Mod Pathol 2007;20(Suppl 2):330A-331A.