Biography

Prof. Francisco Javier Flores Murrieta
Instituto Politécnico Nacional, Mexico

Email: fjfloresmurrieta@prodigy.net.mx

Qualifications
1991  Doctor in Sciences, Centro de Investigación y de Estudios Avanzados del I.P.N., Pharmacology
1988  Master in Sciences, Centro de Investigación y de Estudios Avanzados del I.P.N., Pharmacology
1985  Bachelor in Chemist, Universidad Autónoma de Sinaloa, Pharmacy and Biology


Publications (Selected)
  1. Preza-Murrieta, B., Noa-Carrazana, J. C., Flores-Estévez, N., Estrella-Maldonado, H., Santillán-Mendoza, R., Matilde-Hernández, C., ... & Flores-de la Rosa, F. R. (2024). WRKY transcription factors identified in the transcriptome of Citrus latifolia Tan. and their expression in response to Huanglongbing disease. Journal of General Plant Pathology, 90(6), 309-321.
  2. Vargas-Ruiz, R., Montiel-Ruiz, R. M., Zamilpa, A., Gonzalez-Cortazar, M., Herrera-Ruiz, M. L., Molina-Cabrera, J., ... & Flores-Murrieta, F. J. (2023). Bio-guided study of the antinociceptive, anti-inflammatory, and free-radical scavenging capacity of the leaves of Rhus virens Lindh. ex A. Gray and its possible mechanism of antinociception. Journal of Ethnopharmacology, 300, 115756.
  3. Salazar-Valencia, I. G., Villamil-Ramírez, H., Barajas-Olmos, F., Guevara-Cruz, M., Macias-Kauffer, L. R., García-Ortiz, H., ... & Canizales-Quinteros, S. (2022). Effect of the Melanocortin 4-Receptor Ile269Asn Mutation on Weight Loss Response to Dietary, Phentermine and Bariatric Surgery Interventions. Genes, 13(12), 2267.
  4. Rodríguez-Silverio, J., Sánchez-Mendoza, M. E., Rocha-González, H. I., Reyes-García, J. G., Flores-Murrieta, F. J., López-Lorenzo, Y., ... & Arrieta, J. (2021). Evaluation of the antinociceptive, antiallodynic, antihyperalgesic and anti-inflammatory effect of polyalthic acid. Molecules, 26(10), 2921.
  5. León-Mimila, P., Villamil-Ramírez, H., Macías-Kauffer, L. R., Jacobo-Albavera, L., López-Contreras, B. E., Posadas-Sánchez, R., ... & Canizales-Quinteros, S. (2021). Genome-wide association study identifies a functional SIDT2 variant associated with HDL-C (high-density lipoprotein cholesterol) levels and premature coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology, 41(9), 2494-2508.
  6. Osuna-Padilla, I. A., Briceno, O., Aguilar-Vargas, A., Rodríguez-Moguel, N. C., Villazon-De la Rosa, A., Pinto-Cardoso, S., ... & Reyes-Teran, G. (2020). Zinc and selenium indicators and their relation to immunologic and metabolic parameters in male patients with human immunodeficiency virus. Nutrition, 70, 110585.
  7. Méndez-Sánchez, N., Dibildox-Martinez, M., Sosa-Noguera, J., Sánchez-Medal, R., & Flores-Murrieta, F. J. (2019). Superior silybin bioavailability of silybin–phosphatidylcholine complex in oily-medium soft-gel capsules versus conventional silymarin tablets in healthy volunteers. BMC Pharmacology and Toxicology, 20, 1-6.
  8. Roa-Coria, J. E., Pineda-Farias, J. B., Barragán-Iglesias, P., Quiñonez-Bastidas, G. N., Zúñiga-Romero, Á., Huerta-Cruz, J. C., ... & Rocha-González, H. I. (2019). Possible involvement of peripheral TRP channels in the hydrogen sulfide-induced hyperalgesia in diabetic rats. BMC neuroscience, 20, 1-17.
  9. Quiñonez-Bastidas, G. N., Pineda-Farias, J. B., Flores-Murrieta, F. J., Rodríguez-Silverio, J., Reyes-García, J. G., Godínez-Chaparro, B., ... & Rocha-González, H. I. (2018). Antinociceptive effect of (−)-epicatechin in inflammatory and neuropathic pain in rats. Behavioural Pharmacology, 29(2 and 3), 270-279.
  10. Patiño-Camacho, S. I., Campos, M. D., Beltrán-Villalobos, K., Castro-Vidal, D. A., Montiel-Ruiz, R. M., & Flores-Murrieta, F. J. (2017). Low doses of tizanidine synergize the anti-nociceptive and anti-inflammatory effects of ketorolac or naproxen while reducing of side effects. European journal of pharmacology, 805, 51-57.
  11. Pineda-Farias, J. B., Barragán-Iglesias, P., Valdivieso-Sánchez, A., Rodríguez-Silverio, J., Flores-Murrieta, F. J., Granados-Soto, V., & Rocha-González, H. I. (2017). Spinal 5-HT4 and 5-HT6 receptors contribute to the maintenance of neuropathic pain in rats. Pharmacological Reports, 69(5), 916-923.
  12. L. Cruz-Antonio, F.J. Flores-Murrieta, P. García-López, G. Guízar-Sahagún, G. Castañeda-Hernández. Understanding drug disposition alterations induced by acute spinal cord injury: role of injury level and route of administration for agents submitted to extensive liver metabolism. J Neurotrauma 23: 75-85, 2006.
  13. T. Mixcoatl-Zecuatl, F.J. Flores-Murrieta, V. Granados-Soto V. The nitric oxide-cyclic GMP-protein kinase G-K+ channel pathway participates in the antiallodynic effect of spinal gabapentin. Eur J Pharmacol 531: 87-95, 2006.
  14. I.E. Juárez-Rojop, V. Granados-Soto, J.C. Díaz-Zagoya, F.J. Flores-Murrieta, J.E. Torres-López. Involvement of cholesystokinin in peripheral nociceptive sensitization during diabetes in rats as revealed by the formalin response. Pain 122: 118-125, 2006.
  15. M.C. Carrasco-Portugal, J.E. Herrera, G. Reyes-García, R. Medina-Santillán, F.J. Flores-Murrieta. Comparative bioavailability of two oral suspensions of naproxen sodium. Arzneim Forsch/Drug Res 56: 589-592, 2006.
  16. M.C. Carrasco-Portugal, J.E. Herrera, F.J. Flores-Murrieta. Bioequivalence of two oral formulations of metoprolol. Proc West Pharmacol Soc 49: 42-44, 2006.
  17. H. Aguilar-Mariscal, J. Rodríguez-Silverio, J.E. Torres-López, F.J. Flores-Murrieta. Comparison of the anti-hyperalgesic and anti-inflammatory effects of meloxicam in the rat. Proc West Pharmacol Soc 49: 45-47, 2006.
  18. J.C. Aguilar-Carrasco, N.A. Carrasco-Portugal, M.C. Carrasco-Portugal, J.E. Herrera, F.J. Flores-Murrieta. Comparative bioavailability of two oral formulations of danazol in mexican subjects. Proc West Pharmacol Soc 49: 48-50, 2006.
  19. G. Reyes-García, R. Medina-Santillán, F.J. Flores-Murrieta, N.L. Caram-Salas, V. Granados-Soto. Analgesic effects of B vitamins: a review. Current Topics in Pharmacology 10: 1-31, 2006.
  20. J.E. Torres-López, I.E. Juárez-Rojop, V. Granados-Soto, J.C. Díaz-Zagoya, F.J. Flores-Murrieta, J.U.S. Ortíz-López, J. Cruz-Vera. Peripheral participation of cholecystokinin in the morphine-induced peripheral antinociceptive effect in non-diabetic and diabetic rats. Neuropharmacology 52: 788-795, 2007.
  21. F.J. Flores-Murrieta, M.C. Carrasco-Portugal, G. Reyes-García, R. Medina-Santillán, J. E. Herrera. Bioequivalence of Two Oral Formulations of Glyburide (glibenclamide). Proc. West. Pharmacol. Soc. 50: 64-66, 2007.
  22. B. Pérez-Guillé, M.C. Carrasco-Portugal, A. Alfaro-Rodríguez, N. Labra-Ruiz, R. Soriano-Rosales, F.J. Flores-Murrieta,F. Ayala-Guerrero. Kainic Acid Does Not Modify the Oral Pharmacokinetics of Carbamazepine in Rats Proc. West. Pharmacol. Soc. 50: 67-68, 2007.
  23. M.C. Carrasco-Portugal and F.J. Flores-Murrieta. Gender Differences in the Oral Pharmacokinetics of Fluconazole. Clin. Drug Invest. 27: 851-856, 2007.
  24. H. Aguilar-Mariscal, S.I. Patiño-Camacho, J. Rodríguez-Silverio, J.E. Torres-López, F.J. Flores-Murrieta. Oral Pharmacokinetics of Meloxicam in the Rat Using a High-Performance Liquid Chromatography Method in Micro-Whole-Blood Samples. Methods Find Exp Clin Pharmacol 29: 587-591, 2007.
  25. M.C. Carrasco-Portugal, M. Luján, F.J. Flores-Murrieta. Evaluation of gender in the oral pharmacokinetics of clindamycin in humans. Biopharm Drug Disposit29: 427-430, 2008.
  26. M.C. Carrasco-Portugal, A.G. Camacho-Vieyra, F.J. Flores-Murrieta. The influence of malnutrition on the oral pharmacokinetics of nimesulide in rats. Proc West Pharmacol Soc 51: 52-54, 2008.
  27. M.C. Carrasco-Portugal, F.J. Flores-Murrieta. Comparison of suspension composition on the pharmacokinetics of nimesulide in rats. Proc West Pharmacol Soc 51: 58-59, 2008.
  28. F.J. Flores-Murrieta, M.C. Carrasco-Portugal, C. Landa. Comparison of the oral pharmacokinetics of fluconazole and itraconazole in mexicans. Proc West Pharmacol Soc 51: 63-65, 2008.
  29. M.C. Carrasco-Portugal, F.J. Flores-Murrieta. Comparative bioavailability of two oral formulations of levofloxacin in mexican healthy volunteers. Int J Clin Pharmacol Ther 47: 283-286, 2009.
  30. L. Calderón-Garcidueñas, A Mora-Tiscareño, G. Gómez-Garza, M.C. Carrasco-Portugal, B. Pérez-Guillé, F.J. Flores-Murrieta, G. Pérez-Guillé, N. Osnaya, H. Juárez-Olguin, M.E. Monroy, A. González-Maciel, R. Reynoso-Robles, R. Villarreal-Calderón, S.A. Patel, P. Kumarathasan, R. Vincent, C. Henríquez-Roldán, R. Torres-Jardón, R.R. Maronpot. Effects of a cyclooxygenase-2 preferential inhibitor in young healthy dogs exposed to air pollution. A pilot study. Toxicol Pathol 37: 644-660, 2009.
  31. León-Molina H, Flores-Murrieta FJ. Estrategias para evaluar la intercambiabilidad de fármacos inhalados. Neumología y Cirugía de Tórax 68: 62-70, 2009.
  32. Flores-Murrieta FJ, Carrasco-Portugal MC, Reyes-García G, Medina-Santillán R, Herrera JE. Comparative bioavailability of two oral formulations of omeprazole. Proc West Pharmacol Soc 52: 18-20, 2009.
  33. Montiel-Ruíz RM, Reyes-García G, Flores-Murrieta FJ, Déciga-Campos M. Antinociceptive interaction between benfotiamine and resveratrol in capsaicin-induced licking. Proc West Pharmacol Soc. 52: 67-71, 2009.
  34. Granados-Soto V, Argüelles CF, Rocha-González HI, Godínez-Chaparro B, Flores-Murrieta FJ, Villalón CM. The role of peripheral 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E and 5-HT1F serotonergic receptors in the reduction of nociception in rats. Neuroscience 165: 561-568, 2010.


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