Author(s)

Juan Li¹, Zhenling Duan^2*, Ma Jing³, Xiaotao Jing², Li Bian⁴

¹Gynaecology Department, Dali Bai Minority Autonomous Prefecture People’s Hospital, Yunnan, China.
²Gynaecology Department, First Affiliated Hospital of Kunming Medical University, Yunnan, China.
³Obstetrics Department, First Affiliated Hospital of Kunming Medical University, Yunnan, China.
⁴Pathology Department, First Affiliated Hospital of Kunming Medical University, Yunnan, China.

Müllerian adenosarcomas are rare mixed tumors with low malignant potential, and occur mainly in the uterus. Primary adenosarcomas arising in vaginal endometriosis are even more rarely reported. We report a very rare case with Müllerian adenosarcoma arising from vaginal endometriosis. A 43-year-old nulliparous woman has a history of endometriosis. Due to two parallel fistulas in cervix, severe endometriosis and adenosarcoma, she has undergone radical and multiple surgeries. After the surgery, persistent vaginal vault masses were noticed, and eight resections of the polyps at vaginal stump were performed. For the first six resections, all the pathological examinations showed endometriosis. And the last two resections demonstrated vaginal adenosarcoma. Transition between Müllerian adenosarcoma and endometriosis was gradual. Finally, adenosarcoma associated with endometriosis was diagnosed from recurrent vaginal masses. To our knowledge, this report is the sixth case that primary adenosarcomas arising in vaginal endometriosis. But chemo-therapy and radiation therapy were not taken and the patient remained in a good condition throughout the 9-year follow-up period. In addition, we present a review of the literature. The diagnosis and treatment of the tumor are also discussed.

Endometriosis, Vaginal Stump, Müllerian Adenosarcoma, Case Report

Li, J. , Duan, Z. , Jing, M. , Jing, X. and Bian, L. (2018) Müllerian Adenosarcoma of the Vaginal Stump: A Case Report and Literature Review. Journal of Cancer Therapy, 9, 914-924. doi: 10.4236/jct.2018.911076.