Bone Cancer Mortality in Inner Mongolia from 2008 to 2012


Objective: The aim of our study was to assess bone cancer mortality and the related social factors in Inner Mongolia in China. Methods: We obtained data from the Centers for Disease Control in Inner Mongolia from five monitoring points of the Death Registry System in Inner Mongolia from 2008 to 2012. We calculated the crude mortality rate for bone cancer. The χ2 test was used to examine differences in bone cancer mortality rates between sexes and years. Unconditional logistic regressions were applied to analyze the effect of socio-demographic characteristics by sex. Results: Between 2008 and 2012, the crude mortality rate of bone cancer was 1.12/100000 (95% confidence interval = 1.02-1.21). The bone cancer mortality was 2.24 in men and 1.25 in women, resulting in a male-female ratio of 1.8. No between-year difference in the mortality rate was observed between 2008 and 2012 (men: χ2 = 4.65, P = 0.325; women: χ2 = 2.21, P = 0.698). In general, mortality increased with increasing age. People with a lower education level exhibited an increased risk of bone cancer among both men and women. Jobs involving extensive manual labor decreased the likelihood of bone cancer mortality, and the odds ratio was higher for men than women (0.6 vs. 0.45). Unmarried people had a higher risk for bone cancer than married people. Conclusion: The mortality rate of bone cancer was not significantly different between men and women from 2008 to 2012. The risk of bone cancer increased with age among both sexes. Unmarried people and those with a low education status had an elevated risk of bone cancer, whereas employment in a field involving extensive manual labor appeared to be a protective factor against bone cancer.

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Guo, W. , Hao, W. , Du, M. , Su, Z. , Hu, Y. , Xia, Y. , Su, X. and Sun, J. (2015) Bone Cancer Mortality in Inner Mongolia from 2008 to 2012. Open Journal of Epidemiology, 5, 59-64. doi: 10.4236/ojepi.2015.51008.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Li, J., Thompson, T.D., Miller, J.W., Pollack, L.A. and Stewart, S.L. (2008) Cancer Incidence among Children and Adolescents in the United States, 2001-2003. Pediatrics, 121, e1470-e1477.
[2] Mirabello, L., Troisi, R.J. and Savage, S.A. (2009) Osteosarcoma Incidence and Survival Rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program. Cancer, 115, 1531-1543.
[3] Mirabello, L., Troisi, R.J. and Savage, S.A. (2009) International Osteosarcoma Incidence Patterns in Children and Adolescents, Middle Ages and Elderly Persons. International Journal of Cancer, 125, 229-234.
[4] Felder-Puig, R., Formann, A.K., Mildner, A., Bretschneider, W., Bucher, B., Windhager, R., et al. (1998) Quality of Life and Psychosocial Adjustment of Young Patients after Treatment of Bone Cancer. Cancer, 83, 69-75.<69::AID-CNCR10>3.0.CO;2-A
[5] Troisi, R., Stephansson, O., Jacobsen, J., Tretli, S., Sorensen, H.T., Gissler, M., et al. (2014) Perinatal Characteristics and Bone Cancer Risk in offspring—A Scandinavian Population-Based Study. Acta Oncologica, 53, 830-838.
[6] Colina, M., La Corte, R., De Leonardis, F. and Trotta, F. (2008) Paget’s Disease of Bone: A Review. Rheumatology International, 28, 1069-1075.
[7] Cooper, C., Harvey, N.C., Dennison, E.M. and van Staa, T.P. (2007) Update on the Epidemiology of Paget’s Disease of Bone. Journal of Bone and Mineral Research, 21, P3-P8.
[8] Li, Q, Xin, K., Liu, R., Li, Y., Li, W., Su, X., et al. (2014) Breast Cancer in Inner Mongolia 2009-2011. Open Journal of Epidemiology, 4, 63-68.
[9] Hu, Y., Li, Y., Wang, W., Qian, Y., Hui, C., Xin, K., et al. (2014) The Characteristics of Breast Cancer Mortality in Inner Mongolia between 2008 and 2010. Open Journal of Epidemiology, 4, 135-140.
[10] Xin, K.P., Du, M.L., Liu, Z.Y., Wang, W.R., Qian, Y.G., Liu, L., et al. (2014) Colorectal Cancer Mortality in Inner Mongolia between 2008 and 2012. World Journal of Gastroenterology, 20, 8209-8214.
[11] Guo, W., Xu, W., Huvos, A.G., Healey, J.H. and Feng, C. (1999) Comparative Frequency of Bone Sarcomas among Different Racial Groups. Chinese Medical Journal, 112, 1101-1104.
[12] Hung, G.Y., Horng, J.L., Yen, H.J., Yen, C.C., Chen, W.M., Chen, P.C., et al. (2014) Incidence Patterns of Primary Bone Cancer in Taiwan (2003-2010): A Population-Based Study. Annals of Surgical Oncology, 21, 2490-2498.
[13] dos Santos Silva, I. and Swerdlow, A.J. (1993) Sex Differences in the Risks of Hormone-Dependent Cancers. American Journal of Epidemiology, 138, 10-28.
[14] Holick, M.F., Matsuoka, L.Y. and Wortsman, J. (1989) Age, Vitamin D, and Solar Ultraviolet. Lancet, 2, 1104-1105.
[15] Garland, C.F., Garland, F.C., Gorham, E.D., Lipkin, M., Newmark, H., Mohr, S.B., et al. (2006) The Role of Vitamin D in Cancer Prevention. American Journal of Public Health, 96, 252-261.
[16] Gallo. V., Mackenbach, J.P., Ezzati, M., Menvielle, G., Kunst, A.E., Rohrmann, S., et al. (2012) Social Inequalities and Mortality in Europe—Results from a Large Multi-National Cohort. PLOS ONE, 7, e39013.
[17] Puigpinós, R., Borrell, C., Antunes, J.L., Azlor, E., Pasarín, M.I., Serral, G., et al. (2009) Trends in Socioeconomic Inequalities in Cancer Mortality in Barcelona: 1992-2003. BMC Public Health, 9, 35.
[18] Gremeaux, V., Gayda, M., Lepers, R., Sosner, P., Juneau, M. and Nigam, A. (2012) Exercise and Longevity. Maturitas, 73, 312-317.
[19] Elliot, J.R., Gilchrist, N.L. and Wells, J.E. (1996) The Effect of Socioeconomic Status on Bone Density in a Male Caucasian Population. Bone, 18, 371-373.
[20] Aizer, A.A., Chen, M.H., McCarthy, E.P., Mendu, M.L., Koo, S., Wilhite, T.J., et al. (2013) Marital Status and Survival in Patients with Cancer. Journal of Clinical Oncology, 31, 3869-3876.
[21] Bookwala, J. (2005) The Role of Marital Quality in Physical Health during the Mature Years. Journal of Aging and Health, 17, 85-104.

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