Single Photon Emission Computed Tomography-Computed Tomography (SPECT-CT) Use in Osteosarcoma with Lung Uptake

DOI: 10.4236/crcm.2014.38107   PDF   HTML     3,330 Downloads   3,949 Views  


A 15-year-old patient with osteosarcoma of left distal femur underwent a bone scan with Tc-99m hydroxymethylenediphosphonate (HDP). Whole body bone scan revealed extensive bone and thoracic metastases. Single Photon Emission Computed Tomography-Computed Tomography (SPECT-CT) of the thorax localized the uptake at pleura and lung nodules. In this case study we want to share our experience using SPECT-CT.

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Hamid, K. and Sarji, S. (2014) Single Photon Emission Computed Tomography-Computed Tomography (SPECT-CT) Use in Osteosarcoma with Lung Uptake. Case Reports in Clinical Medicine, 3, 491-495. doi: 10.4236/crcm.2014.38107.

Conflicts of Interest

The authors declare no conflicts of interest.


[1] Kühne, T., Imbach, P. and Arceci, R.J. (2006) Osteosarcoma. In: Pediatric Oncology, Springer, Berlin, Heidelberg, 159-164.
[2] Elgazzar, A.H. and Shehab, D. (2006) Musculoskeletal System. In: The Pathophysiologic Basis of Nuclear Medicine, Springer, Berlin, Heidelberg, 132-208.
[3] Franzius, C., Sciuk, J., Daldrup-Link, H.E., Jürgens, H. and Schober, O. (2000) FDG-PET for Detection of Osseous Metastases from Malignant Primary Bone Tumours: Comparison with Bone Scintigraphy. European Journal of Nuclear Medicine and Molecular Imaging, 27, 1305-1311.
[4] Beyer, T., Freudenberg, L., Townsend, D. and Czernin, J. (2011) The Future of Hybrid Imaging—Part 1: Hybrid Imaging Technologies and SPECT/CT. Insights into Imaging, 2, 161-169.
[5] Aras, M., Dede, F., Ones, T., Dane, F., Inanir, S., Erdil, T.Y., et al. (2012) 99mTc-MDP-and 18F-FDG-avid Metastatic Liver Lesion: The Similarities and Differences between 2 Modalities. Clinical Nuclear Medicine, 37, 380-381.
[6] Othman, S. and El-Desouki, M. (2003) Bone Scan Appearance in Aggressive Osteogenic Sarcoma with Pleural, Lung, Bone, and Soft-Tissue Metastases. Clinical Nuclear Medicine, 28, 926.
[7] Mebarki, M., Medjahedi, A., Menemani, A., Betterki, S., Terki, S. and Berber, N. (2013) Osteosarcoma Pulmonary Metastasis Mimicking Abnormal Skeletal Uptake in Bone Scan: Utility of SPECT/CT. Clinical Nuclear Medicine, 38, e392-e394.

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