Portal Venous-Phase CT of the Liver in Patients without Chronic Liver Damage: Does Portal-Inflow Tracking Improve Enhancement and Image Quality?

Abstract

Purpose: This study was undertaken to determine if portal-inflow bolus tracking outperforms aortic bolus tracking with respect to the image quality of contrast-enhanced portal venous-phase CT of the liver in patients without chronic liver damage. Materials and Methods: Contrast-enhanced CT of the liver was performed in 132 consecutive patients without chronic liver damage. Patients were prospectively assigned to three protocols: Protocol A—a portal venous-phase scan delay of 6 seconds after superior mesenteric venous (SMV) enhancement increased by 70 HU or 14 seconds after SMV enhancement was visually confirmed, and Protocols B and C—40 and 50 seconds, respectively, after abdominal aortic enhancement increased by 100 HU. Enhancement (ΔHU) of abdominal aorta, portal trunk, and liver parenchyma and diagnostic acceptability were assessed. Results: ΔHU of aorta was higher for protocol A than for protocols B and C (P < 0.05), whereas ΔHU of portal trunk was higher for protocol B than for protocols A and C (P < 0.05). ΔHUs of liver were similar in three protocols. No difference was found between diagnostic a  ptabilities of three protocols. Conclusion: Portal-inflow bolus tracking did not outperform aortic tracking in terms of optimization of portal venous-phase CT in patients without chronic liver damage.

Share and Cite:

M. Kanematsu, H. Watanabe, H. Kondo, S. Goshima, H. Kawada and Y. Noda, "Portal Venous-Phase CT of the Liver in Patients without Chronic Liver Damage: Does Portal-Inflow Tracking Improve Enhancement and Image Quality?," Open Journal of Radiology, Vol. 3 No. 3, 2013, pp. 112-116. doi: 10.4236/ojrad.2013.33018.

Conflicts of Interest

The authors declare no conflicts of interest.

References

[1] J. P. Heiken, J. A. Brink, B. L. McClennan, S. S. Sagel, H. P. Forman and J. DiCroce, “Dynamic Contrast-Enhanced CT of the Liver: Comparison of Contrast Medium Injec tion Rates and Uniphasic and Biphasic Injection Proto cols,” Radiology, Vol. 187, No. 2, 1993, pp. 327-331.
[2] Y. Yamashita, I. Ogata, J. Urata and M. Takahashi, “Ca vernous Hemangioma of the Liver: Pathologic Correla tion with Dynamic CT Findings,” Radiology, Vol. 203, No. 1, 1997, pp. 121-125.
[3] J. F. Platt, I. R. Francis, J. H. Ellis and K. A. Reige, “Liver Metastases: Early Detection Based on Abnormal Contrast Material Enhancement at Dual-Phase Helical CT,” Radiology, Vol. 205, No. 1, 1997, pp. 49-53.
[4] J. H. Oliver 3rd, R. L. Baron, M. P. Federle, B. C. Jones and R. Sheng, “Hypervascular Liver Metastases: Do Unenhanced and Hepatic Arterial Phase CT Images Affect Tumor Detection?” Radiology, Vol. 205, No. 3, 1997, pp. 709-715.
[5] E. K. Paulson, V. G. McDermott, M. T. Keogan, D. M. DeLong, M. G. Frederick and R. C. Nelson, “Carcinoid Metastases to the Liver: Role of Triple-Phase Helical CT,” Radiology, Vol. 206, No. 1, 1998, pp. 143-150.
[6] L. Kopka, J. Rodenwaldt, U. Fischer, D. W. Mueller, J. W. Oestmann and E. Grabbe, “Dual-Phase Helical CT of the Liver: Effects of Bolus Tracking and Different Vol umes of Contrast Material,” Radiology, Vol. 201, No. 2, 1996, pp. 321-326.
[7] L. van Hoe, G. Marchal, A. L. Baert, S. Gryspeerdt and L. Mertens, “Determination of Scan Delay Time in Spiral CT-Angiography: Utility of a Test Bolus Injection,” Jour nal of Computer Assisted Tomography, Vol. 19, No. 2, 1995, pp. 216-220. doi:10.1097/00004728-199503000-00009
[8] M. Kanematsu, S. Goshima, H. Kondo, H. Nishibori, H. Kato, R. Yokoyama, T. Miyoshi, H. Hoshi, M. Onozuka and N. Moriyama, “Optimizing Scan Delays of Fixed Duration Contrast Injection in Contrast-Enhanced Bi phasic Multidetector-Row CT for the Liver and the De tection of Hypervascular Hepatocellular Carcinoma,” Jour nal of Computer Assisted Tomography, Vol. 29, No. 2, 2005, pp. 195-201. doi:10.1097/01.rct.0000155062.50236.59
[9] F. A. Burgener and D. J. Hamlin, “Contrast Enhancement of Focal Hepatic Lesions in CT: Effect of Size and His tology,” American Journal of Roentgenology, Vol. 140, No. 2, 1983, pp. 297-301. doi:10.2214/ajr.140.2.297
[10] K. Hanafusa, I. Ohashi, Y. Himeno, S. Suzuki and H. Shibuya, “Hepatic Hemangioma: Findings with Two Phase CT,” Radiology, Vol. 196, No. 2, 1995, pp. 465-469.
[11] J. P. Heiken, J. A. Brink, B. L. McClennan, S. S. Sagel, T. M. Crowe and M. V. Gaines, “Dynamic Incremental CT: Effect of Volume and Concentration of Contrast Material and Patient Weight on Hepatic Enhancement,” Radiology, Vol. 195, No. 2, 1995, pp. 353-357.

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.