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Evaluation of Biological Effects of Nanosystems of Directed Transport in Experiments in Vivo and Their Application Possibilities in Anti-Tumor Therapy

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DOI: 10.4236/anp.2013.22023    3,565 Downloads   6,067 Views  

ABSTRACT

The aim of the investigations was to evaluate benefits of the directed transport system - a nanocomposite, based on cisplatin and magnetite combined with local action of constant magnetic field on the tumor, in experiments in vivo in animals with transplantable Guerin carcinoma. Animals were divided into 5 groups according to the type of agent. We showed that nanocomposite in combination with static magnetic field exercises more prominent anti-tumor activity than cisplatin alone. It should be noted that regardless of the therapeutic agent, in Guerin carcinoma we observed

Conflicts of Interest

The authors declare no conflicts of interest.

Cite this paper

Chekhun, V. , Naleskina, L. , Polishchuk, L. , Todor, I. , Demash, D. and Lukianova, N. (2013) Evaluation of Biological Effects of Nanosystems of Directed Transport in Experiments in Vivo and Their Application Possibilities in Anti-Tumor Therapy. Advances in Nanoparticles, 2, 145-153. doi: 10.4236/anp.2013.22023.

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