Universal RNA editing in a human liver at the fetal stage

Dong Liu, Cong Liu, Xiyin Wang, Sigurdur Ingvarsson, Huiping Chen

Department of Medical Genetics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Institute for Experimental Pathology and Faculty of Medicine, University of Iceland, Keldur, Iceland.

DOI: 10.4236/ojgen.2012.23021                

Abstract

It is known that RNA editing occurs in human cells, which can change the information transmission from DNA to RNA and proteins. Most previous studies have focused on editing of the mRNAs. Here we reported that several kinds of RNAs, including miRNA, rRNA, mRNA, miscRNA and unknown RNA, exhibited base editing in a human fetal liver. Several editing types are displayed. Our data reveals that RNA editing may occur in different species of RNAs.

Keywords

RNA Editing; miRNA; rRNA; mRNA; miscRNA; Fetal Liver

Conflicts of Interest

The authors declare no conflicts of interest.

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