Amyloïdosis Complicating Behcet’s Disease ()
Author(s)
Amel Harzallah1,2,
Hayet Kaaroud El Jery1,2,
Mariem Hajji1,2,
Ikram Mami1,2,
Rim Goucha2,3,
Sami Turki1,2,
Fethi Ben Hamida2,3,
Madiha Mahfoudhi1,2,
Taieb Ben Abdallah1,2
ABSTRACT
Background: Behcet’s disease is
a vasculitis affecting several organs. A renal involvement is rarely described.
It is most of the time about a renal amyloidosis. Patients and methods: It is a
descriptive retrospective study concerning the patients followed in our department
for a Behcet’s disease having presented a renal amyloidosis. Results: It is about 4 men with average age of 38.25 years old. The renal
involvement was revealed after an average delay of 5.7 years by a nephrotic
syndrome in all cases. A renal insufficiency was noted in 3 cases with an
average serum creatinine of 587 μmol/l (127 - 1490). The type of the
amyloidosis was AA in 2 cases. The treatment contained colchicines in every
case. The evolution was marked by the worsening of the renal function leading
to end stage renal disease in 3 cases. Death occurred in 1 case and one patient
lost to follow up. Discussion: Renal amyloidosis can complicate the evolution
of a Behcet’s disease. It occurs generally 1 to 10 years after the beginning of
the disease. Once installed, it evolves generally towards the chronic renal
insufficiency and can condition the forecast of this affection. Conclusion: Amyloidosis
is a rare complication of the Behcet’s disease. Its screening is so desirable
to improve the renal prognosis of these patients.
Share and Cite:
Harzallah, A. , El Jery, H. , Hajji, M. , Mami, I. , Goucha, R. , Turki, S. , Hamida, F. , Mahfoudhi, M. and Abdallah, T. (2016) Amyloïdosis Complicating Behcet’s Disease.
Open Journal of Clinical Diagnostics,
6, 42-46. doi:
10.4236/ojcd.2016.63008.