American Journal of Plant Sciences

Volume 3, Issue 7 (July 2012)

ISSN Print: 2158-2742   ISSN Online: 2158-2750

Google-based Impact Factor: 1.20  Citations  h5-index & Ranking

Inhibitory Effects of Several Spices on Inflammation Caused by Advanced Glycation Endproducts

HTML  Download Download as PDF (Size: 1017KB)  PP. 995-1002  
DOI: 10.4236/ajps.2012.327118    5,402 Downloads   10,114 Views  Citations

ABSTRACT

Advanced glycation endproducts (AGEs) is implicated in the pathogenesis of diabetic complications. Inhibiting the formation of AGEs and interfering with AGEs-mediated inflammation are two practicable strategies for developing a dietary adjuvant against diabetic complications. This study evaluated the protective capacities against diabetic complications of several spices based on their inhibition of the formation of AGEs in an in vitro BSA/glucose system and on the AGEs-induced production of proinflammatory cytokine in RAW 264.7 macrophages. Among the tested spices, cinnamon exhibited most strongly inhibited both the formation of AGEs and the AGEs-induced production of nitric oxide, interleukin-6 and tumor necrosis factor-α. Additionally, correlative results revealed that the capacity of spices to inhibit the formation of AGEs is attributable to phenolic compounds and, in contrast, the capacity to inhibit AGEs-induced inflammation is attributable to condensed tannin. This investigation demonstrates the potential of cinnamon to serve as a dietary adjuvant against diabetic complications.

Share and Cite:

S. Ho and P. Chang, "Inhibitory Effects of Several Spices on Inflammation Caused by Advanced Glycation Endproducts," American Journal of Plant Sciences, Vol. 3 No. 7A, 2012, pp. 995-1002. doi: 10.4236/ajps.2012.327118.

Cited by

[1] Phytochemical profile, anti-glycation effect, and advanced glycation end-products protein cross-link breaking ability of Sclerocarya birrea stem-bark crude …
Journal of Herbmed …, 2022
[2] Diet-Derived Antioxidants and Their Role in Inflammation, Obesity and Gut Microbiota Modulation
2021
[3] Inhibitory effect and cross-link breaking activity of Moringa oleifera leaf crude extracts on fructose-derived advanced glycation end-products
2021
[4] Pharmacological Properties of Ceylon Cinnamon
2020
[5] Cinnamaldehyde protects from methylglyoxal‐induced vascular damage: Effect on nitric oxide and advanced glycation end products
2019
[6] Tannins in Artemisia: the hidden treasure of prophylaxis
2018
[7] Green cardamom increases Sirtuin-1 and reduces inflammation in overweight or obese patients with non-alcoholic fatty liver disease: a double-blind …
2018
[8] Antiamylase, Anticholinesterases, Antiglycation, and Glycation Reversing Potential of Bark and Leaf of Ceylon Cinnamon (Cinnamomum zeylanicum Blume) In Vitro
Evidence-Based Complementary and Alternative Medicine, 2017
[9] Un-Junk Your Diet: How to Shop, Cook, and Eat to Fight Inflammation and Feel Better Forever
2017
[10] Les 100 idées reçues qui vous empêchent d'aller bien: Alimentation, sommeil, cerveau, sport, hormones, intestin: le guide santé pour tous
2017
[11] Antiamylase, anticholinesterases, antiglycation, and glycation reversing potential of bark and leaf of Ceylon cinnamon (Cinnamomum zeylanicum Blume) in …
2017
[12] Antioxidant and starch hydrolase inhibitory properties of extracts of the antidiabetic herbPterocarpus marsupium
2016
[13] Antioxidant and starch hydrolase inhibitory properties of extracts of the antidiabetic herb Pterocarpus marsupium
Israel Journal of Plant Sciences, 2016
[14] The Mechanisms of Inhibition of Advanced Glycation End Products Formation through Polyphenols in Hyperglycemic Condition
Planta medica, 2016
[15] Les 100 idées reçues qui vous empêchent d'aller bien: Alimentation, sommeil, sport, hormones, génétique... Ce qu'il faut savoir pour être en bonne santé
2015
[16] Inhibitory effect of plant extract on tumor necrosis factor-α formation from carboxymethyllysine stimulated macrophages
2015
[17] Metabolic and biological profile of autochthonous Vitis vinifera L. ecotypes
Food & function, 2015
[18] Analysis of glycation induced protein cross-linking inhibitory effects of some antidiabetic plants and spices
BMC complementary and alternative medicine, 2015
[19] Strong protein glycation inhibitory potential of clove and coriander
British J Pharmaceutical Res, 2015
[20] Les 100 idées reçues qui vous empêchent d'aller bien
Leduc. s Éditions, 2015
[21] The Mechanisms of Inhibition of Advanced Glycation End Products Formation through Polyphenols in Hyperglycemic Condition.
Planta medica, 2015
[22] Protective Role of Ginger on the Induced Diabetic Retinopathy in Adult Albino Rats
Journal of American Science, 2014
[23] Determination of superoxide dismutase mimetic activity in common culinary herbs
SpringerPlus, 2014
[24] Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells
International journal of oncology, 2013
[25] Experimentally Induced Diabetic Keratopathy in Albino Rats and the Possible Protective Role of Ginger
Journal of American Science, 2013
[26] Experimentally induced diabetic keratopathy in albino rats and the possible protective role of ginger.
2013
[27] Biochemical, antioxidant and antineoplastic properties of Italian saffron (Crocus sativus L.)
American Journal of Plant Sciences, 2012

Journals Menu
Follow SCIRP
Contact us
+1 323-425-8868
customer@scirp.org
WhatsApp +86 18163351462(WhatsApp)
Click here to send a message to me 1655362766
Paper Publishing WeChat

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.