Prof. Nelson Leung-Sang TANG

Department of Chemical Pathology

The Chinese University of Hong Kong

Professor

Email: nlstang2014@gmail.com

Qualifications

2002 Doctor of Medicine (CUHK)

1998 Accredited Clinical Biochemists

1997 Fellow of the Royal College of Pathologists of Australasia

1997 Fellow of the Hong Kong Society of Clinical Chemistry

Publications (Selected)

1. Estrada K, Tang NL (100 in 180 authors) et al. (2012). Genome-wide metaanalysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nature Genetics 44(5):491-501.
2. Wan X, Yang C, Yang Q, Xue H, Fan X, Tang NL, Yu W. (2010) BOOST: A fast approach to detecting gene-gene interactions in genome-wide case-control studies. Am J Hum Genet. 87(3):325-40.
3. Wan X, Yang C, Yang Q, Xue H, Tang NL, Yu W. (2010) Detecting two-locus associations allowing for interactions in genome-wide association studies. Bioinformatics. 26(20):2517-25.
4. Khor CC, Tang NL (32 of 35 authors) et al (2010). CISH and susceptibility to infectious diseases. N. Engl. J. Med. 362(22):2092–101.
5. Liu XG, Tang NL (15 of 21 authorsrs) et al. (2009). Genome-wide association and replication studies identified TRHR as an important gene for lean body mass. Am J Hum Genet. 84(3):418-23
6. Tang NL, Chan PK, Hui DS, To KF, Zhang W, Chan FK, Sung JJ, Lo YM (2007). Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infection. Nature Genetics 39(6):691-2.
7. Chan IH, Leung TF, Tang NL, Li CY, Sung YM, Wong GW, Wong CK, Lam CW (2006). Gene-gene interactions for asthma and plasma total IgE concentration in Chinese children. J Allergy Clin Immunol 117(1): 127-33.
8. Tang NL, Hwu WL, Chan RT, Law LK, Fung LM, Zhang WM (2002). A founder mutation (R254X) of SLC22A5 (OCTN2) in Chinese primary carnitine deficiency patients. Hum. Mutat. 20(3):232.
9. Tang NL, Ganapathy V, Wu X, Hui J, Seth P, Yuen PM, Wanders RJ, Fok TF, Hjelm NM (1999). Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency. Hum. Mol. Genet. 8(4):655–60.
10. Tang, NLS; Pang, CP; Yeo, W; Choy, KW; Lam, PK; Suen, M; Law, LK; King, WWK; Johnson, P; Hjelm, M (1999). Prevalence of mutations in the BRCA1 gene among Chinese patients with breast cancer. Journal of the National Cancer Institute, 91 (10): 882-885.
11. Wang X, Tang NL, Leung CC, Kam KM, Yew WW, Tam CM, Chan CY. Association of polymorphisms in the Chr18q11.2 locus with tuberculosis in Chinese population. Hum Genet. 2013 Jun;132(6):691-5. doi: 10.1007/s00439-013-1282-7. Epub 2013 Mar 3. PubMed PMID: 23456169.
12. Ji LD, Chai PF, Zhou BB, Tang NL, Xing WH, Yuan F, Fei LJ, Zhang LN, Xu J. Lack of association between polymorphisms from genome-wide association studies and tuberculosis in the Chinese population. Scand J Infect Dis. 2013 Apr;45(4):310-4. doi: 10.3109/00365548.2012.726739. Epub 2012 Oct 31. PubMed PMID: 23113532.
13. Tang NL, Chan CY, Leung CC, Tam CM, Blackwell J. Tuberculosis susceptibility genes in the chemokine cluster region of chromosome 17 in Hong Kong Chinese. Hong Kong Med J. 2011 Dec;17 Suppl 6:22-5. PubMed PMID: 22147355.
14. Khor CC, Vannberg FO, Chapman SJ, Guo H, Wong SH, Walley AJ, Vukcevic D, Rautanen A, Mills TC, et al. CISH and susceptibility to infectious diseases. N Engl J Med. 2010 Jun 3;362(22):2092-101. doi: 10.1056/NEJMoa0905606. Epub 2010 May 19. PubMed PMID: 20484391; PubMed Central PMCID: PMC3646238.
15. Tang NL, Fan HP, Chang KC, Ching JK, Kong KP, Yew WW, Kam KM, Leung CC, Tam CM, Blackwell J, Chan CY. Genetic association between a chemokine gene CXCL-10 (IP-10, interferon gamma inducible protein 10) and susceptibility to tuberculosis. Clin Chim Acta. 2009 Aug;406(1-2):98-102. doi: 10.1016/j.cca.2009.06.006. Epub 2009 Jun 10. PubMed PMID: 19523460.

Profile Details

http://www.cpy.cuhk.edu.hk/Research/NelsonTang.htm