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Biography

Dr. Chunhai Hao

Emory University School of Medicine,USA


Email: chao@emory.edu

Qualifications

1997 F.R.C.P.C. University of Western Ontario

1991 Ph.D., University of Saskatchewan

1985 M.Sc., Norman Bethune University of Medical Sciences

1981 M.D., Jilin Medical College


Publications

  1. Bellail AC, Olson J, Yang X, Chen Z, and Hao C. (2012), A20 ubiquitin ligase-mediated polyubiquitination of RIP1 inhibits caspase-8 cleavage and TRAIL-induced apoptosis in glioblastoma.Cancer Discov2(2), 140-55.
  2. Song JH, Tse MG, Bellail AC, Khuri F, Phuphanich S, Kneteman NM, and Hao C. (2007), Lipid rafts and non-rafts mediate tumor necrosis factor-related apoptosis-inducing ligand-induced apoptotic and non-apoptotic signals in non-small cell lung carcinoma cells.Cancer Res67(14): 6946-6955.
  3. Song JH, Bellail AC, Tse MC, Yong VW, and Hao C.(2006), Human astrocytes are resistant to Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.J Neurosci26(12):3299-3308.
  4. Wang CX, Song JH, Song DK, Yong VW, Shuaib A, and Hao C.(2006), Cyclin-dependent kinase-5 prevents neuronal apoptosis through ERK-mediated upregulation of Bcl-2.Cell Death Differ13(7):1203-1212.
  5. Hao C, Song JH, Hsi B, Lewis J, Song DK, Petruk KC, Tyrrell LJ, and Kneteman NM. (2004), TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice.Cancer Res64 (23):8502-8506.
  6. Song JH,Song DK,Pyrzynska P, Petruk KC, Van Meir EG, and Hao C. (2003),TRAIL induces apoptosis in human glioma cells through extrinsic and intrinsic pathways.Brain Pathol13 (4):539 -553.
  7. Song JH,Song DK, Herlyn M, Petruk KC, and Hao C. (2003),Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1b-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells.Clin Cancer Res9 (11):4255-4266.
  8. Yang BF, Xiao C, Roa WH,Krammer PH, and Hao C. (2003),Calcium/calmodulin-dependent protein kinase II regulation of c-FLIP expression and phosphorylation in modulation of Fas-mediated signaling in malignant glioma cells.J Biol Chem278 (9):7043-7050.
  9. Xiao C, Yang BF, Asadi N, Beguinot F, andHao C. (2002), Tumor necrosis factor-related apoptosis-inducing ligand-induced death inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells.J Biol Chem277(28):25020-25025.
  10. Hao C, Beguinot F, Condorelli G, Trencia A, Van Meir EG, Yong WV, Parney IF, Roa WH, and Petruk KC. (2001), Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apoptosis in human malignant glioma cells.Cancer Res61(3):1162-1170.


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