Dr. Alexander A. Konstantinov
Moscow State
University, Russia
E-mail: konst@genebee.msu.su
Qualifications
1987
Doctor of Biological Sciences (the highest scientific degree in Russia;
approx. equivalent to British “Doctor of Sciences”); speciality, Biochemistry
and Biophysics
1985 PhD
in Biochemistry, Moscow State University
1972
BS/MS summa cum laude in Biochemistry, School of
Biology, Moscow State University
Publications (Selected)
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Arutjunjan,A.M., Konstantinov,A.A. and Sharonov,Yu.A. Magnetic
circular dichroism and magnetooptical rotatory dispersion of submitochondrial
particles at room and liquid nitrogen temperatures. (1974) FEBS Lett. 46,
317-320.
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Konstantinov,A.A. On the mechanism of H+-electrochemical
potential generation in the first two sites of the respiratory chain. (1975)
Dokl.Akad.Nauk SSSR 220, 736-739 (in Russian).
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Konstantinov,A.A., Maslov,S.P., Severina,I.I. and
Skulachev,V.P. Protamine as a specific inhibitor of electron transfer from
cytochrome c to cytochrome a at the outer
face of the mitochondrial membrane (1975) Biokhimiya 40, 401-407 (in Russian).
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Kamensky,Yu.A., Konstantinov,A.A. and Jasaitis,A.A.
Studies on cytochromes b in beef heart submitochondrial
particles in the presence of the succinate/fumarate redox buffer (1975)
Biokhimiya 40, 1022-1031 (in Russian).
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Kiselev,A.V. and Konstantinov,A.A. Studies on the nature
of redox equivalents transferred by cytochrome c and
localization of this respiratory chain component at the outer face of the
mitochondrial membrane. (1976) Bioorg.Chem.(USSR) 2, 253-258 (in Russian).
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Artzatbanov,V.Yu., Konstantinov,A.A. and Skulachev,V.P.
Localization of cytochrome a at the inner side of the
mitochondrial coupling membrane.(1976) Dokl.Akad.Nauk SSSR, 228, 1222-1225 (in
Russian).
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Ruuge,E.K. and Konstantinov,A.A. EPR signal of Q
semiquinone with unusual relaxation characteristics. (1976) Biofizika 21,
586-588 (in Russian).
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Peskin,A.V., Zbarsky,I.B. and Konstantinov,A.A. Studies
on superoxide dismutase activity in tumour tissues. (1976) Dokl.Akad.Nauk SSSR
220, 751-754 (in Russian).
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Tikhonov,A.N., Burbaev,D.Sh., Grigolava,I.V.,
Konstantinov,A.A., Ksenzenko,M.Yu. and Ruuge,E.K. Interaction of ubisemiquinone
with the high-potential iron-sulfur centre of succinate dehydrogenase of
submitochondrial particles. EPR study at 240 and 12 K. (1977) Biofizika 22,
734-736 (in Russian).
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Konstantinov,A.A. and Ruuge,E.K. ESR studies on the coenzyme
Q semiquinone in submitochondrial particles from beef heart (1977) Bioorg.Chem.
(USSR) 3, 787-799 (in Russian).
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Peskin,A.V., Koen,Ya.M., Zbarsky,I.B. and
Konstantinov,A.A. Superoxide dismutase and glutathione peroxidase activities in
tumors. (1977) FEBS Lett. 78, 41-45.
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Grigolava,I.V. and Konstantinov,A.A. Components of
coupling site II accesible to p-diazobenzenesulfonate from the
outside of mitochondria. (1977) FEBS Lett. 78, 36-40.
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Konstantinov,A.A. and Ruuge,E.K. Semiquinone Q in the
respiratory chain of electron transfer particles. (1977) FEBS Lett. 81, 137-141.
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Artzatbanov,V.Yu., Konstantinov,A.A.and Skulachev,V.P.
Studies on cytochrome oxidase localization in the coupling membrane:
interaction of cytochrome a with H+-ions from
mitochondrial matrix.(1977) Dokl.Akad.Nauk SSSR 237, 461-464 (in Russian).
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Konstantinov,A.A. Role of protons in the mitochondrial
respiratory chain coupling site 3 mechanism: cytochrome oxidase as an
electron-proton generator of membrane potential. (1977) Dokl.Akad.Nauk USSR 237,
713-716 (in Russian).
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Subchinsky,V.K., Konstantinov,A.A. and Ruuge,E.K. Studies
on the spin probes interaction with the submitochondrial particle membrane
(1978) Biofizika 23, 57-60 (in Russian).
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Smirnova,I.A., Konstantinov,A.A. and Skulachev,V.P.
Direct measurement of membrane potential generation by submitochondrial
particles (1978) Dokl.Akad.Nauk SSSR 241, 970-973 (in Russian).
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Artzatbanov,V.Yu., Konstantinov,A.A. and Skulachev,V.P.
Involvement of intramitochondrial protons in redox reactions of cytochrome a.(1978).
FEBS Lett.87, 180-185.
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Arutjunjan,A.M., Kamensky,Yu.A., Milgrom,E., Surkov,S.,
Konstantinov,A.A. and Sharonov,Yu.A. Is mitochondrial cytochrome b-566/558
a single hemoprotein or two individual components? A magnetic circular
dichroism study.(1978) FEBS Lett.95, 40-44.
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Koen,Ya.M., Peskin,A.V., Baru,V.A., Fedorchenko,V.V.,
Zbarsky,I.B. and Konstantinov,A.A. Transport of RNA from rat liver cell nuclei in
vitro. Effect of superoxide dismutase on the release of rapidly labeled RNA
from isolated nuclei (1978) Biokhimiya 43, 2124-2129 (in Russian).
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Grigolava,I,V. and Konstantinov,A.A. Localization of
cytochrome b-566 at the outer side of the coupling mitochondrial
membrane. (1979) Biokhimiya 44, 1329-1332 (in Russian).
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Andreev,I.M, Artzatbanov,V.Yu.,Konstantinov,A.A. and
Skulachev,V.P. Cyanide binding with ferricytochrome a in rat
liver mitochondria. (1979) Dokl.Akad.Nauk SSSR 244, 1013-1017 (in Russian).
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Kamensky Yu.A., Artzatbanov, V.Yu., Shevchenko,D.V. and
Konstantinov,A.A. Effect of antimycin on the redox-linked protonation of
cytochromes b in the mitochondrial respiratory chain. (1979)
Dokl.Akad.Nauk SSSR 249, 994-997 (in Russian).
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Smirnova,I.A., Tikhonov,A.N., Konstantinov, A.A. and
Ruuge,E.K. On the free radical centres in chromatophores and reaction centre
preparations from Rhodospirillum rubrum . (1979) Biofizika 24,
761-762 (in Russian).
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Surkov,S.A. and Konstantinov,A.A. Dibromothymoquinone
interaction with the mitochondrial respiratory chain. Further evidence for the
Q-cycle. (1980) FEBS Lett. 109, 283-288.
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Konstantinov,A.A., Skulachev,V.P. and Smirnova,I.A.
Membrane potential generation by submitochondrial particles associated with a
lipid-impregnated filter. (1980) FEBS Lett. 114, 302-306.
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Peskin,A.V., Zbarsky,I.B. and Konstantinov,A.A. A novel
type of superoxide generating system in nuclear membranes from Hepatoma 22a
ascites cells. (1980) FEBS Lett. 17, 44-48.
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Konstantinov,A.A., Kamensky,Yu.A., Ksenzenko,M.Yu. and
Surkov,S. Studies on the Q-cycle in the mitochondrial respiratory chain. (1980)
EBEC Reports, v.1, 63-64.
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Artzatbanov,V.Yu. and Konstantinov,A.A. Effect of
antimycin on the Em/pH-dependence of b cytochromes
in beef heart submitochondrial particles. (1980) EBEC Reports, v.1, 73-74.
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Grigolava,I.V., Ksenzenko,M.Yu., Konstantinov,A.A.,
Tikhonov,A.N., Kerimov,T.M. and Ruuge,E.K. Tiron as a spin-trap for superoxide
radicals generated by the respiratory chain of submitochondrial particles.
(1980) Biokhimiya 45, 75-81 (in Russian).
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Ksenzenko,M.Yu.and Konstantinov,A.A. Effect of
2,3-dimercaptopropanol on electron transfer in the coupling site 2 of the
respiratory chain: evidence for the Q-cycle. (1980) Biokhimiya 45, 343-354 (in
Russian).
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Peskin,A.V., Zbarsky, I.B.and Konstantinov,A.A. Studies on
the electron transfer systems in the microsomal and nuclear membranes from rat
liver and Hepatoma 22a. (1981) Biokhimiya 46, 579-589 (in Russian).
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Smirnova,I.A., Konstantinov,A.A. and Skulachev,V.P. The
role of cofactors in membrane potential generation by Rhodospirillun
rubrum chromatophores incorporated into a teflon filter. (1981)
Biokhimiya 46, 1155-1166 (in Russian).
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Konstantinov,A.A., Kunz,W.S. and Kamensky,Yu.A. The Q
cycle in the mitochondrial respiratory chain. (1981) In:"Chemiosmotic
Proton Circuits in Biological Membranes" (Skulachev,V.P. and Hinkle,P.C.,
eds.) pp.123-146, Addison-Wesley, Reading.
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Kunz,W.S., Ksenzenko,M.Yu. and Konstantinov,A.A.
Different effects of antimycin, HOQNO and mucidin on electron transfer in bc -site
of the mitochondrial respiratory chain. (1982) EBEC Reports, v.2, 381-382.
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Konstantinov,A.A., Kaminskaya,O.P. and Grigoriev,V.A.
Photochemical injection of protons into ice (1982) Dokl.Akad.Nauk SSSR 264,
488-490 (In Russian).
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Ksenzenko,M.Yu., Konstantinov,A.A.,Tikhonov,A.N. and
Ruuge,E.K. Inhibition of H2O2 and O2- generation
in the respiratory chain treated by 2,3-dimercaptopropanol. (1982) Biokhimiya
47, 1570-1572 (in Russian).
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Grigolava,I.V., Konstantinov,A.A., Ksenzenko,M.Yu.,
Tikhonov,A.N. and Ruuge,E.K. Interaction of ubisemiquinone with succinate
dehydrogenase and the cytochrome chain of mitochondria. (1982) Biokhimiya 47,
1970-1982 (in Russian).
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Artzatbanov,V.Yu., Grigoriev,V.A. and Konstantinov,A.A.
Redox-dependent protonation of cytochrome oxidase hemes in beef heart submitochondrial
particles. (1983) Biokhimiya 48, 48-53 (in Russian).
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Andreev,I.M., Myakotina,O.L., Popova,E.Yu. and
Konstantinov,A.A. Acceleration of cyanide binding with cytochrome c oxidase
by cytochrome c.(1983) Biokhimiya 48, 219-223 (in Russian).
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Andreev,I.M. and Konstantinov,A.A. Reaction of the
oxidized cytochrome oxidase with cyanide. Effects of pH, cytochrome c and
membrane environment. (1983) Bioorg.Chem. (Moscow) 9, 216-227 (in Russian).
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Kunz,W.S. and Konstantinov,A.A. Energy-linked spectral
shift of ferrocytochrome b in beef heart submitochondrial
particles. (1983) FEBS Lett. 152, 53-56.
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Ksenzenko,M.Yu., Konstantinov,A.A., Khomutov,G.B.,
Tikhonov,A.N. and Ruuge,E.K. Effect of electron transfer inhibitors on
superoxide generation in the cytochrome bc1 site of
the mitochondrial respiratory chain. (1983) FEBS Lett. 155, 19-24.
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Kunz,W.S. and Konstantinov,A.A. Effect of bc1 -site
inhibitors on the midpoint potentials of mitochondrial cytochromes b.
(1983) FEBS Lett. 155, 237-240.
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Kunz,W.S., Kushnarenko,S.V. and Konstantinov,A.A.
Differences in the effects of antimycin and 2-nonyl-4-hydroxyquinoline-N-oxide
on the oxidation-reduction of mitocondrial cytochromes b. (1983)
Biokhimiya 48, 1456-1462 (in Russian).
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Tkachenko,T.A., Kunz,W.S. and Konstantinov,A.A.
Localization of the interaction site of the oxidized form of N,N,N’,N’-tetramethyl-p-phenylene
diamine (Wurster’s Blue) with bc1 site of the
mitochondrial respiratory chain. (1983) Dokl.Akad.Nauk SSSR 273, 242-245 (in
Russian).
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Kunz,W.S., Konstantinov,A.A. Cytochrome b reduction
in mitochondria and submitochondrial particles. Evidence for heme b-562
localisation at the M-side of the mitochondrial membrane. (1984) FEBS Lett.
175, 100-104.
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Peskin,A.V., Zbarsky,I.B. and Konstantinov,A.A. Superoxide
dismutase-sensitive NADP(H) dependent reduction of oxygen by the membrane-bound
redox chains of liver microsomes and Hepatoma nuclei in the presence of
adrenaline. (1984) Biochem.Internat. 8, 733-738.
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Kunz,W.S., Konstantinov,A.A., Tsofina,L. and Liberman,E,A.
Localization of a ferricyanide-reactive site of cytochrome bc1 complex,
possibly of cytochrome b or ubisemiquinone,at the outer face
of submitochondrial particles. (1984) FEBS Lett. 172, 261-266.
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Peskin,A.V., Zbarsky,I.B. and Konstantinov,A.A.
HAD(P)H-dependent oxidation of adrenaline by nuclear membranes from Hepatoma
22a. (1984) Biol.Membr.(Moscow) 1, 721-727 (in Russian).