Prof. Yuhua Ruan

Chinese Center for Disease Control and Prevention, China

Email: ruanyuhua92@gmail.com

Qualifications

1999  Ph.D., Shanghai Medical University, SOPH

1996  M.S., Suzhou Medical College

Publications (Selected)

1. Ruan Yuhua, Chen Kanglin, Hong Kunxue, et al. Community-Based survey of HIV transmission modes among injection drug users in Sichuan, China. Sexually Transmitted Diseases, 2004, 31(10): 623-62
2. Ruan Yuhua, Qin Guangming, Liu Shizhu, Qian Han-zhu, et al. HIV Incidence and factors contributed to retention in a 12-month follow-up study of injection drug users in Sichuan Province, China. Journal of Acquired Immune Deficiency Syndromes, 2005, 39(4):459-463
3. Wei L, Chen J, Rodolph M, Beauchamp G, Masse B, Wang S, Li R, Ruan YH, et al. HIV prevalence among injection drug users in rural Guangxi China. Addiction 2006;101:1493-1498.
4. Ruan YH, Cao X, Qian HZ, et al. Syphilis among female sex workers in southwestern China: Potential for HIV transmission. Sex Transm Dis 2006, 33(12):719-723
5. 5. Qian Han-Zhu, Schumacher Joseph E, Chen Huey T, Ruan Yuhua. Injection drug use and HIV/AIDS in China: Review of current situation, prevention and policy implications, Harm Reduction Journal 2006, 3:4   doi:10.1186/1477-7517-3-4
6. Xu Jian-qing, Wang Jian-jun, Han Li-feng, Xu Chen, Ruan Yuhua, et al. Epidemiology, clinical and laboratory characteristics of currently alive HIV-1 infected former blood donors naive to antiretroviral therapy in Anhui Province, China. Chin Med J (Engl), 2006; 119(23): 1941-1948
7. Liu HW, Hong KX, Ma J, Yuan L, Liu S, Chen JP, Zhang YZ, Ruan YH, Xu JQ, Shao YM., 2006, 119(19):1616-1621. Identification of HIV-1 specific T lymphocyte responses in highly exposed persistently seronegative Chinese. Chin Med J (Engl)
8. Zhang XY, Huang XG, Xu JQ, Li SW, Jiang SL, Zhang XX, Li DL, Ruan YH, Xing H, Shao YM. HIV-specific T cell immunity across the entire HIV genome in Chinese men who have sex with men. Chin Med J (Engl), 2006;119(23):1958-1965.
9. Lu Yin, Guangming Qin, Han-Zhu Qian, Yu Zhu, Wei Hu, Li Zhang, Kanglin Chen, Yunxia Wang, Shizhu Liu, Feng Zhou, Hui Xing, Ruan Yuhua, Ning Wang, Yiming Shao. Continued spread of HIV among injecting drug users in southern Sichuan Province, China, Harm Reduction Journal, 2007, 4:6, doi:10.1186/1477-7517-4-6.
10. Wei L, Chen J, Rodolph M, Beauchamp G, Li R, Wang S, Ruan YH, et al. HIV incidence, retention, and changes of high-risk behaviors among rural injection drug users in Guangxi, China. Subst Abus. 2006, 27(4):53-61.
11. Ruan YH, Li DL, Li XX, Qian HZ, et al. Relation between syphilis and HIV infections among men who have sex with men in Beijing, China. Sex Transm Dis. 2007, 34(8):592-597.
12. Zhang Y, Shan H, Trizzino J, Ruan YH, et al. HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. International Journal of Infectious Diseases, 2007, 11, 318-323
13. Yin Lu, Guangming Qin, Ruan Yuhua, Han-Zhu Qian, Chun Hao, Lianzhi Xie, Xanglin Chen, Yafeng Zhang, Yaowen Xia, Junlin Wu, Shenghan Lai, and Yiming Shao. Nonfatal overdose among heroin users in Southwestern China. The American Journal of Drug and Alcohol Abuse. 2007, 33(4): 505-516
14. Guo YF, Ma LY, Yuan L, Wang SH, Sun JP, Xu WS, Xu JQ, Xing H, Ong KX, Zhang XY, Ruan YH, Zhang YX, Shao YM. R5 to X4 coreceptor switch of human immunodeficiency virus type 1 B' and B'/C recombinant subtype isolates in China. Chin Med J (Engl). 2007, 120(6):522-525.
15. Wang Jun, Li Fan, Mo Lanrong, Li Lin, Guan Yongsheng, Hao Chun, Yin Lu, LI Xinxu, Chen xi, Ruan Yuhua, Shao yiming. Factors associated with retention in a community-based methadone maintenance treatment among drug users in urumqi, xinjiang uigur autonomous region. Chinese Journal of Epidemiology, 2007, 28(1): 37-41.
16. Chen J, Hong K, Jia M, Liu H, Zhang Y, Liu S, Zhang X, Zhao H, Peng H, Ma P, Xing H, Ruan YH, Williams KL, Yu XG, Altfeld M, Walker BD, Shao Y. Human immunodeficiency virus type 1 specific cytotoxic T lymphocyte responses in Chinese infected with HIV-1 B'/C Recombinant (CRF07_BC). Retrovirology, 2007, 4:62 doi:10.1186/1742-4690-4-62.
17. Song YH, Meng ZF, Xing H, Ruan YH,et al. Analysis of HIV-1 CRF07_BC gag p6 sequences indicating novel deletions in the central region of p6. Arch Virol, 2007, 152 (8); 1553-1558.
18. Liao L, Xing H, Li X, Ruan YH, Zhang Y, Qin G, Shao Y.Genotypic Analysis of the Protease and Reverse Transcriptase of HIV Type 1 Isolates from Recently Infected Injecting Drug Users in Western China. AIDS Res Hum Retroviruses, 2007, 23(8):1062-1065.
19. Yuhua Ruan, Guangming Qin, Lu Yin, Kanglin Chen, Han-Zhu Qian, Chun Hao, Shu Liang, Junling Zhu, Hui Xing, Kunxue Hong, Yiming Shao. Incidence of HIV, hepatitis C and hepatitis B viruses among injection drug users in southwestern China: a 3-year follow-up study. AIDS, 2007, 21 (suppl 8):S39–S46.
20. Ruijun Zhang, Jianqing Xu, Kunxue Hong, Lin Yuan, Hong Peng, Haili Tang, Pengfei Ma, Yuanzhi Zhang, Hui Xing, Yuhua Ruan and Yiming Shao. Increased NKG2A found in cytotoxic natural killer subset in HIV-1 patients with advanced clinical status. AIDS, 2007, 21 (suppl 8):S9–S17.
21. Xiaoxi Zhang, Chen Wang, Wang Hengwei, Xinxu Li, Dongliang Li, Yuhua Ruan, Xiaoyan Zhang and Yiming Shao. Risk factors of HIV infection and prevalence of co-infections among men who have sex with men in Beijing, China. AIDS, 2007, 21 (suppl 8):S53–S57.
22. Xiaoyan Zhang, Shenwei Li, Xinping Li, Xinxu Li, Jianqing Xu, Dongliang Li, Yuhua Ruan, Hui Xing, Xiaoxi Zhang and Yiming Shao. Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China. AIDS, 2007, 21 (suppl 8):S59–S65.
23. Yuhua Ruan, Li Zhang, Jun Wei, Han-Zhu Qian, et al. Risk Factors for Death in Subjects with Transfusion-Related HIV Infection in Rural China. AIDS Patient Care and STDs, 2008, 22(2): 95-97.
24. Lu Yin, Yuanzhi Zhang, Han-Zhu Qian, Baoling Rui, Lijiang Zhang, Junling Zhu, Yongsheng Guan, Yunxia Wang, Qingchun Li, Yuhua Ruan, Yiming Shao. Willingness of Chinese injection drug users to participate in HIV vaccine trials. Vaccine, 2008, 26: 762-768.
25. Yican Zhou, Yiming Shao, Yuhua Ruan, Jianqing Xu, Zhien Ma, Changlin Mei, Jianhong Wu. Modeling and prediction of HIV in China: Transmission rates structured by infection ages. Mathematical Biosciences and Engineering, 2008, 5(2): 430-418.
26. Li SW, Zhang XY, Li XX, Wang MJ, Li DL, Ruan YH, Zhang XX, Shao YM 2008;121(12):1105-8.. Detection of recent HIV-1 infections among men who have sex with men in Beijing during 2005-2006. Chin Med J (Engl).
27. Qian HZ, Hao C, Ruan Y, Cassell HM, Chen K, Qin G, Yin L, Schumacher JE, Liang S, Shao Y. Impact of methadone on drug use and risky sex in China. Journal of Substance Abuse Treatment, 2008;34(4):391-7
28. Haishan Li, Hong Peng, Pengfei Ma, Yuhua Ruan, Bing Su, Xinping Ding, Chen Xu, C. David Pauza, Yiming Shao. Association between Vg2Vd2 T cells and disease progression after infection with closely related strains of HIV in China. Clinical Infectious Diseases, 2008; 46:1466-72.
29. Li Zhang, Junling Zhu, Baoling Rui, Yuanzhi Zhang, Lijiang Zhang, Lu Yin, Yuhua Ruan, Han-Zhu Qian, Yiming Shao. High HIV risk among Uigur minority ethnic drug users in northwestern China. Tropical Medicine & International Health, 2008, doi:10.1111/j.1365-3156.2008.02071.x.
30. Qian HZ, Li Q, Yao H, Ruan Y, Kristensen S, Schumacher JE, Pan SW, Shao Y, Kimerling ME. Tuberculosis co-morbidity and perceptions about health care among HIV-infected plasma donors in rural China. Southeast Asian J Trop Med Public Health. 2009;40(1):108-12
31. Zhang X, Xu J, Peng H, Ma Y, Han L, Ruan Y, Su B, Wang N, Shao Y. HCV coinfection associated with slower disease progression in HIV-infected former plasma donors naive to ART. PLoS ONE. 2008;3(12):e3992.
32. Yuhua Ruan, Fengji Luo, Yujiang Jia, Xinxu Li, Qingchun Li, Hongyuan Liang, Xiaoxi Zhang, Dongliang Li, Wei Shi, Jennifer M. Freeman, Sten H. Vermund, Yiming Shao. Risk factors for syphilis and prevalence of HIV, hepatitis B and C among men who have sex with men in Beijing, China: Implications for HIV prevention. AIDS Behav,2009;13(4):663-70.
33. Yuhua Ruan, Han-Zhu Qian, Dongliang Li, Wei Shi, Qingchun Li, Hongyuan Liang, Ye Yang, Fengji Luo, Sten H. Vermund, Yiming Shao. Willingness to be circumcised for preventing HIV among Chinese men who have sex with men. AIDS Patient Care and STDs,2009; 23(5):315-21.
34. Ruan Y, Jia Y, Zhang X, Liang H, Li Q, Yang Y, Li D, Zhou Z, Luo F, Shi W, Shao Y. Incidence of HIV-1, Syphilis, Hepatitis B, and Hepatitis C Virus Infections and Predictors Associated With Retention in a 12-Month Follow-Up Study Among Men Who Have Sex With Men in Beijing, China. J Acquir Immune Defic Syndr. 2009; 52(5): 604-10.
35. Yuan L, Ma L, Fan X, Feng Y, Peng H, Zhao Q, Ruan Y, Levy JA, Shao Y. CD8+ cell noncytotoxic antiviral response in long-term HIV-1 infected former blood donors in China.Curr HIV Res. 2009;7(4):437-40.
36. Jie Lou, Jianhong Wu, Li Chen, Yuhua Ruan, Yiming Shao. A sex-role-preference model for HIV transmission among men who have sex with men in China. BMC Public Health. 2009 Nov 18;9 Suppl 1:S10.
37. Wang Z, Liu HW, Hong KX, Yu ZJ, Chen JP, Ruan YH, Kan QC, Shao YM. Complete human immunodeficiency virus-1 specific T lymphocyte response to Chinese human immunodeficiency virus-1 B/C chronic infectors. Biomed Environ Sci. 2009;22(6):522-8.
38. Yuhua Ruan, Stephen W. Pan, Eric Chamot, Han-zhu Qian, Dongliang Li, Qing-chun Li, Hong-yuan Liang, Patricia Spittal, Yiming Shao, Sibylle Kristensen. Sexual mixing patterns among social networks of HIV-positive and HIV-negative Beijing men who have sex with men: a multilevel comparison using roundtable network mapping. AIDS Care, Vol. 00, No. 00, 2010, 1_10
39. Feng YM, Wan YM, Liu LX, Qiu C, Ma PF, Peng H, Ruan YH, Han LF, Hong KX, Xing H, Shao YM. HIV-Specific IL-2(+) and/or IFN-γ(+) CD8(+) T Cell Reponses during Chronic HIV-1 Infection in Former Blood Donors. Biomed Environ Sci. 2010 Oct;23(5):391-401.
40. Yuhua Ruan, Hui Xing, Xia Wang, Heng Tang, Zhe Wang, Hongwei Liu, Bin Su, Jianjun Wu, Hanping Li, Lingjie Liao, Jingyun Li, Julia Wei Wu, Yiming Shao. Virologic outcomes of first-line HAART and associated factors among Chinese patients with HIV in three sentinel antiretroviral treatment sites. Trop Med Int Health. 2010 15(11):1357-63.
41. Dongliang Li, Yujiang Jia, Yuhua Ruan, Yingjie Liu, Qingchun Li, Hongyuan Liang, Zhenhai Zhou, Fengji Luo, Xiaoxi Zhang, Shulin Jiang, Wei Shi, Hui Xing, Yiming Shao. Correlates of incident infections for HIV, syphilis, and hepatitis B virus in a cohort of men who have sex with men in Beijing. AIDS Patient Care and STDs, 2010;2 4(9):595-602.
42. Li Q, Luo F, Zhou Z, Li S, Liu Y, Li D, Shi W, Raymond HF, Yuhua Ruan, Shao Y. Willingness to participate in HIV vaccine clinical trials among Chinese men who have sex with men. Vaccine. 2010;28(29):4638-43.
43. Gao L, Zhou F, Li XW, Yang Yu, Ruan YH, Jin Q. Anal HPV Infection in HIV-positive Men Who Have Sex with Men from China. PLoS one 2010; 5:e15256.
44. Ruan Y, Pan SP, Chamot E, Qian HZ, Li D, Li QC, Liang HY, Spittal P, Shao Y, Kristensen S. Sexual mixing patterns among social networks of HIV-positive and HIVnegative Beijing men who have sex with men: a multilevel comparison using roundtable network mapping. AIDS Cares 2011 Mar 10:1-12.