[1]
|
Newby, A.C. (2007) Metalloproteinases and Vulnerable Atherosclerotic Plaques. Trends in Cardiovascular Medicine, 17, 253-258. https://doi.org/10.1016/j.tcm.2007.09.001
|
[2]
|
Naghavi, M., Libb, P., Falk, E., Casscells, S.W., Litovsky, S., Rumberger, J., et al. (2003) From Vulnerable Plaque to Vulnerable Patient: A Call for New Definitions and Risk Assessment Strategies: Part II. Circulation, 108, 1772-1778. https://doi.org/10.1161/01.CIR.0000087481.55887.C9
|
[3]
|
Liu, X.Q., Mao, Y., Wang, B., Lu, X.T., Bai, W.W., Sun, Y.Y., et al. (2014) Specific Matrix Metalloproteinases Play Different Roles in Intraplaque Angiogenesis and Plaque Instability in Rabbits. PLoS ONE, 9, e107851. https://doi.org/10.1371/journal.pone.0107851
|
[4]
|
Virmani, R., Kolodgie, F.D., Burke, A.P., Finn, A.V., Gold, H.K., Tulenko, T.N., et al. (2005) Atherosclerotic Plaque Progression and Vulnerability to Rupture: Angiogenesis as a Source of Intraplaque Hemorrhage. Arteriosclerosis, Thrombosis, and Vascular Biology, 25, 2054-2061. https://doi.org/10.1161/01.ATV.0000178991.71605.18
|
[5]
|
Kim, V.N. (2005) MicroRNA Biogenesis: Coordinated Cropping and Dicing. Nature Reviews Molecular Cell Biology, 6, 376-385. https://doi.org/10.1038/nrm1644
|
[6]
|
Siddeek, B., Inoubli, L., Lakhdari, N., Rachel, P.B., Fussell, K.C., Schneider, S., et al. (2014) MicroRNAs as Potential Biomarkers in Diseases and Toxicology. Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 764-765, 46-57. https://doi.org/10.1016/j.mrgentox.2014.01.010
|
[7]
|
Bartel, D.P. (2004) MicroRNAs: Genomics, Biogenesis, Mechanism, and Function. Cell, 116, 281-297. https://doi.org/10.1016/S0092-8674(04)00045-5
|
[8]
|
Fichtlscherer, S., De, R.S., Fox, H., Schwietz, T., Fischer, A., Liebetrau, C., et al. (2010) Circulating microRNAs in Patients with Coronary Artery Disease. Circulation Research, 107, 677-684. https://doi.org/10.1161/CIRCRESAHA.109.215566
|
[9]
|
Vasa-Nicotera, M., Chen, H., Tucci, P., Yang, A.L., Saintigny, G., Menghini, R., et al. (2011) MiR-146a Is Modulated in Human Endothelial Cell with Aging. Atherosclerosis, 217, 326-330. https://doi.org/10.1016/j.atherosclerosis.2011.03.034
|
[10]
|
Kuppusamy, K.T., Jones, D.C., Sperber, H., Madan, A., Fischer, K.A., Rodriguez, M.L., et al. (2015) Let-7 Family of MicroRNA Is Required for Maturation and Adult-Like Metabolism in Stem Cell-Derived Cardiomyocytes. Proceedings of the National Academy of Sciences of the United States of America, 112, E2785-E2794. https://doi.org/10.1073/pnas.1424042112
|
[11]
|
Kuppusamy, K.T., Sperber, H. and Ruohola-Baker, H. (2013) MicroRNA Regulation and Role in Stem Cell Maintenance, Cardiac Differentiation and Hypertrophy. Current Molecular Medicine, 13, 757-764. https://doi.org/10.2174/1566524011313050007
|
[12]
|
Zampetaki, A. and Mayr, M. (2012) MicroRNAs in Vascular and Metabolic Disease. Circulation Research, 110, 508-522. https://doi.org/10.1161/CIRCRESAHA.111.247445
|
[13]
|
Chen, K.C., Wang, Y.S., Hu, C.Y., Chang, W.C., Liao, Y.C., Dai, C.Y., et al. (2011) OxLDL Up-Regulates microRNA-29b, Leading to Epigenetic Modifications of MMP-2/MMP-9 Genes: A Novel Mechanism for Cardiovascular Diseases. FASEB Journal, 25, 1718-1728. https://doi.org/10.1096/fj.10-174904
|
[14]
|
Lovren, F., Pan, Y., Quan, A., Singh, K.K., Shukla, P.C., Gupta, N., et al. (2012) MicroRNA-145 Targeted Therapy Reduces Atherosclerosis. Circulation, 126, S81-S90. https://doi.org/10.1161/circulationaha.111.084186
|
[15]
|
Thornton, J.E. and Gregory, R.I. (2012) How Does Lin28 let-7 Control Development and Disease? Trends in Cell Biology, 22, 474-482. https://doi.org/10.1016/j.tcb.2012.06.001
|
[16]
|
Mendell, J.T. and Olson, E.N. (2012) MicroRNAs in Stress Signaling and Human Disease. Cell, 148, 1172-1187. https://doi.org/10.1016/j.cell.2012.02.005
|
[17]
|
Frangogiannis, N.G. (2014) MicroRNAs and Endothelial Function: Many Challenges and Early Hopes for Clinical Applications. Journal of the American College of Cardiology, 63, 1695-1696. https://doi.org/10.1016/j.jacc.2013.10.056
|
[18]
|
Bye, A., Rosjo, H., Nauman, J., Silva, G.J., Follestad, T., Omland, T., et al. (2016) Circulating microRNAs Predict Future Fatal Myocardial Infarction in Healthy Individuals—The HUNT Study. Journal of Molecular and Cellular Cardiology, 97, 162-168. https://doi.org/10.1016/j.yjmcc.2016.05.009
|
[19]
|
Chen, K.C., Hsieh, I.C., Hsi, E., Wang, Y.S., Dai, C.Y., Chou, W.W., et al. (2011) Negative Feedback Regulation between microRNA let-7g and the oxLDL Receptor LOX-1. Journal of Cell Science, 124, 4115-4124. https://doi.org/10.1242/jcs.092767
|
[20]
|
Libby, P., Lichtman, A.H. and Hansson, G.K. (2013) Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans. Immunity, 38, 1092-1104. https://doi.org/10.1016/j.immuni.2013.06.009
|
[21]
|
Karunakaran, D., Geoffrion, M., Wei, L., Gan, W., Richards, L., Shangari, P., et al. (2016) Targeting Macrophage Necroptosis for Therapeutic and Diagnostic Interventions in Atherosclerosis. Science Advances, 2, e1600224. https://doi.org/10.1126/sciadv.1600224
|
[22]
|
Legein, B., Temmerman, L., Biessen, E.A. and Lutgens, E. (2013) Inflammation and Immune System Interactions in Atherosclerosis. Cellular and Molecular Life Sciences, 70, 3847-3869. https://doi.org/10.1007/s00018-013-1289-1
|
[23]
|
Hansson, G.K. and Hermansson, A. (2011) The Immune System in Atherosclerosis. Nature Immunology, 12, 204-212. https://doi.org/10.1038/ni.2001
|
[24]
|
Liao, Y.C., Wang, Y.S., Guo, Y.C., Lin, W.L., Chan, M.H. and Juo, S.H. (2014) Let-7g Improves Multiple Endothelial Functions through Targeting Transforming Growth Factor-Beta and SIRT-1 Signaling. Journal of the American College of Cardiology, 63, 1685-1694. https://doi.org/10.1016/j.jacc.2013.09.069
|
[25]
|
Rom, S., Dykstra, H., Zuluaga-Ramire, V., Reichenbach, N.L. and Persidsky, Y. (2015) MiR-98 and let-7g Protect the Blood-Brain Barrier under Neuroinflammatory Conditions. Journal of Cerebral Blood Flow & Metabolism, 35, 1957-1965. https://doi.org/10.1038/jcbfm.2015.154
|
[26]
|
Medbury, H.J., Williams, H. and Fletcher, J.P. (2014) Clinical Significance of Macrophage Phenotypes in Cardiovascular Disease. Clinical and Translational Medicine, 3, 63. https://doi.org/10.1186/s40169-014-0042-1
|
[27]
|
Hofnagel, O., Robenek, H. and Cathepsin, K. (2009) Boon or Bale for Atherosclerotic Plaque Stability? Cardiovascular Research, 81, 242-243. https://doi.org/10.1093/cvr/cvn343
|
[28]
|
Vacek, T.P., Rehman, S., Neamtu, D., Yu, S., Givimani, S. and Tyagi, S.C. (2015) Matrix Metalloproteinases in Atherosclerosis: Role of Nitric Oxide, Hydrogen Sulfide, Homocysteine, and Polymorphisms. Vascular Health and Risk Management, 11, 173-183. https://doi.org/10.2147/VHRM.S68415
|
[29]
|
Austin, K.M., Covic, L. and Kuliopulos, A. (2013) Matrix Metalloproteases and PAR1 Activation. Blood, 121, 431-439. https://doi.org/10.1182/blood-2012-09-355958
|
[30]
|
Heo, S.H., Cho, C.H., Kim, H.O., Jo, Y.H., Yoon, K.S., Lee, J.H., et al. (2011) Plaque Rupture Is a Determinant of Vascular Events in Carotid Artery Atherosclerotic Disease: Involvement of Matrix Metalloproteinases 2 and 9. Journal of Clinical Neurology, 7, 69-76. https://doi.org/10.3988/jcn.2011.7.2.69
|
[31]
|
Allahverdian, S., ChehroudiM, A.C., McManus, B.M., Abraham, T. and Francis, G.A. (2014) Contribution of Intimal Smooth Muscle Cells to Cholesterol Accumulation and Macrophage-Like Cells in Human Atherosclerosis. Circulation, 129, 1551-1559. https://doi.org/10.1161/CIRCULATIONAHA.113.005015
|
[32]
|
Johnson, J.L., Devel, L., Czarny, B., George, S.J., Jackson, C.L., Rogakos, V., et al. (2011) A Selective Matrix Metalloproteinase-12 Inhibitor Retards Atherosclerotic plaque Development in Apolipoprotein E-Knockout Mice. Arteriosclerosis, Thrombosis, and Vascular Biology, 31, 528-535. https://doi.org/10.1161/ATVBAHA.110.219147
|
[33]
|
Abbas, A., Aukrust, P., Russell, D., Krohg-Sorensen, K., Almas, T., Bundgaard, D., et al. (2014) Matrix Metalloproteinase 7 Is Associated with Symptomatic Lesions and Adverse Events in Patients with Carotid Atherosclerosis. PLoS ONE, 9, e84935. https://doi.org/10.1371/journal.pone.0084935
|
[34]
|
Jin, Z.X., Xiong, Q., Jia, F., Sun, C.L., Zhu, H.T. and Ke, F.S. (2015) Investigation of RNA Interference Suppression of Matrix Metalloproteinase-9 in Mouse Model of Atherosclerosis. International Journal of Clinical and Experimental Medicine, 8, 5272-5278.
|
[35]
|
Libby, P. (2001) What Have We Learned about the Biology of Atherosclerosis? The Role of Inflammation. American Journal of Cardiology, 88, 3J-6J. https://doi.org/10.1016/s0002-9149(01)01879-3
|
[36]
|
Yoon, Y.W., Kwon, H.M., Hwang, K.C., Choi, E.Y., Hong, B.K., Kim, D., et al. (2005) Upstream Regulation of Matrix Metalloproteinase by EMMPRIN. Extracellular Matrix Metalloproteinase Inducer in Advanced Atherosclerotic Plaque. Atherosclerosis, 180, 37-44. https://doi.org/10.1016/j.atherosclerosis.2004.11.021
|
[37]
|
Newby, A.C. (2008) Metalloproteinase Expression in Monocytes and Macrophages and Its Relationship to Atherosclerotic Plaque Instability. Arteriosclerosis, Thrombosis, and Vascular Biology, 28, 2108-2114. https://doi.org/10.1161/ATVBAHA.108.173898
|
[38]
|
Cimmino, G., Ragni, M., Cirillo, P., Petrillo, G., Loffredo, F., Chiariello, M., et al. (2013) C-Reactive Protein Induces Expression of Matrix Metalloproteinase-9: A Possible Link between Inflammation and Plaque Rupture. International Journal of Cardiology, 168, 981-986. https://doi.org/10.1016/j.ijcard.2012.10.040
|
[39]
|
Benjamin, M.M. and Khalil, R.A. (2012) Matrix Metalloproteinase Inhibitors as Investigative Tools in the Pathogenesis and Management of Vascular Disease. Exs, 103, 209-279. https://doi.org/10.1007/978-3-0348-0364-9_7
|
[40]
|
Qian, P., Zuo, Z., Wu, Z., Meng, X., Li, G., Wu, Z., et al. (2011) Pivotal Role of Reduced Let-7g Expression in Breast Cancer Invasion and Metastasis. Cancer Research, 71, 6463-6474. https://doi.org/10.1158/0008-5472.CAN-11-1322
|
[41]
|
Colles, S.M., Maxson, J.M., Carlson, S.G. and Chisolm, G.M. (2001) Oxidized LDL-Induced Injury and Apoptosis in Atherosclerosis. Potential Roles for Oxysterols. Trends in Cardiovascular Medicine, 11, 131-138. https://doi.org/10.1016/S1050-1738(01)00106-2
|
[42]
|
Mallat, Z. and Tedgui, A. (2000) Apoptosis in the Vasculature: Mechanisms and Functional Importance. British Journal of Pharmacology, 130, 947-962. https://doi.org/10.1038/sj.bjp.0703407
|
[43]
|
Schwerk, C. and Schulze-Osthoff, K. (2003) Non-Apoptotic Functions of Caspases in Cellular Proliferation and Differentiation. Biochemical Pharmacology, 66, 1453-1458. https://doi.org/10.1016/S0006-2952(03)00497-0
|
[44]
|
Acarin, L., Villapol, S., Faiz, M., Rohn, T.T., Castellano, B. and Gonzalez, B. (2007) Caspase-3 Activation in Astrocytes Following Postnatal Excitotoxic Damage Correlates with Cytoskeletal Remodeling but Not with Cell Death or Proliferation. Glia, 55, 954-965. https://doi.org/10.1002/glia.20518
|
[45]
|
Nhan, T.Q., Liles, W.C. and Schwartz, S.M. (2006) Physiological Functions of Caspases beyond Cell Death. American Journal of Pathology, 169, 729-737. https://doi.org/10.2353/ajpath.2006.060105
|
[46]
|
Zhang, Y., Chen, N., Zhang, J. and Tong, Y. (2013) Hsa-Let-7g miRNA Targets Caspase-3 and Inhibits the Apoptosis Induced by OX-LDL in Endothelial Cells. International Journal of Molecular Sciences, 14, 22708-22720. https://doi.org/10.3390/ijms141122708
|
[47]
|
Ding, Z., Wang, X., Khaidakov, M., Liu, S. and Mehta, J.L. (2012) MicroRNA Hsa-Let-7g Targets Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Expression and Inhibits Apoptosis in Human Smooth Muscle Cells. Experimental Biology and Medicine, 237, 1093-1100. https://doi.org/10.1258/ebm.2012.012082
|
[48]
|
Ding, Z., Wang, X., Schnackenberg, L., Khaidakov, M., Liu, S., Singla, S., et al. (2013) Regulation of Autophagy and Apoptosis in Response to OX-LDL in Vascular Smooth Muscle Cells, and the Modulatory Effects of the microRNA Hsa-Let-7g. International Journal of Cardiology, 168, 1378-1385. https://doi.org/10.1016/j.ijcard.2012.12.045
|
[49]
|
Wu, K., Yang, Y., Zhao, J. and Zhao, S. (2016) BAG3-Mediated miRNA Let-7g and Let-7i Inhibit Proliferation and Enhance Apoptosis of Human Esophageal Carcinoma Cells by Targeting the Drug Transporter ABCC10. Cancer Letters, 371, 125-133. https://doi.org/10.1016/j.canlet.2015.11.031
|
[50]
|
Sluimer, J.C., Gasc, J.M., van Wanroij, J.L., Kisters, N., Groeneweg, M., Sollewijn Gelpke, M.D., et al. (2008) Hypoxia, Hypoxia-Inducible Transcription Factor, and Macrophages in Human Atherosclerotic Plaques Are Correlated with Intraplaque Angiogenesis. Journal of the American College of Cardiology, 51, 1258-1265. https://doi.org/10.1016/j.jacc.2007.12.025
|
[51]
|
Lin, H.L., Zhang, L., Liu, C.X., Xu, X.S., Tang, M.X., Lv, H.X., et al. (2010) Haemin-Enhanced Expression of Haem Oxygenase-1 Stabilizes Erythrocyte-Induced Vulnerable Atherosclerotic Plaques. British Journal of Pharmacology, 160, 1484-1495. https://doi.org/10.1111/j.1476-5381.2010.00799.x
|
[52]
|
Lin, H.L., Xu, X.S., Lu, H.X., Zhang, L., Li, C.J., Tang, M.X., et al. (2007) Pathological Mechanisms and Dose Dependency of Erythrocyte-Induced Vulnerability of Atherosclerotic Plaques. Journal of Molecular and Cellular Cardiology, 43, 272-280. https://doi.org/10.1016/j.yjmcc.2007.05.023
|
[53]
|
de Vries, M.R. and Quax, P.H. (2016) Plaque Angiogenesis and Its Relation to Inflammation and Atherosclerotic Plaque Destabilization. Current Opinion in Lipidology, 27, 499-506. https://doi.org/10.1097/MOL.0000000000000339
|
[54]
|
Marsch, E., Theelen, T.L., Demandt, J.A., Jeurissen, M., van Gink, M., Verjans, R., et al. (2014) Reversal of Hypoxia in Murine Atherosclerosis Prevents Necrotic Core Expansion by Enhancing Efferocytosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 34, 2545-2553. https://doi.org/10.1161/ATVBAHA.114.304023
|
[55]
|
Bot, I., Jukema, J.W., Lankhuizen, I.M., van Berkel, T.J. and Biessen, E.A. (2011) Atorvastatin Inhibits Plaque Development and Adventitial Neovascularization in ApoE Deficient Mice Independent of Plasma Cholesterol Levels. Atherosclerosis, 214, 295-300. https://doi.org/10.1016/j.atherosclerosis.2010.11.008
|
[56]
|
Michel, J.B., Virmani, R., Arbustini, E. and Pasterkamp, G. (2011) Intraplaque Haemorrhages as the Trigger of Plaque Vulnerability. European Heart Journal, 32, 1977-1985. https://doi.org/10.1093/eurheartj/ehr054
|
[57]
|
Madrigal-Matute, J., Rotllan, N., Aranda, J.F. and Fernandez-Hernando, C. (2013) MicroRNAs and Atherosclerosis. Current Atherosclerosis Reports, 15, 322. https://doi.org/10.1007/s11883-013-0322-z
|
[58]
|
Tabuchi, T., Satoh, M., Itoh, T. and Nakamura, M. (2012) MicroRNA-34a Regulates the Longevity-Associated Protein SIRT1 in Coronary Artery Disease: Effect of Statins on SIRT1 and microRNA-34a Expression. Clinical Science, 123, 161-171. https://doi.org/10.1042/CS20110563
|
[59]
|
Tan, K.S., Armugam, A., Sepramaniam, S., Lim, K.Y., Setyowati, K.D., Wang, C.W., et al. (2009) Expression Profile of MicroRNAs in Young Stroke Patients. PLoS ONE, 4, e7689. https://doi.org/10.1371/journal.pone.0007689
|
[60]
|
Rippe, C., Blimline, M., Magerko, K.A., Lawson, B.R., LaRocca, T.J., Donato, A.J., et al. (2012) MicroRNA Changes in Human Arterial Endothelial Cells with Senescence: Relation to Apoptosis, eNOS and Inflammation. Experimental Gerontology, 47, 45-51. https://doi.org/10.1016/j.exger.2011.10.004
|
[61]
|
Santulli, G. (2015) MicroRNAs Distinctively Regulate Vascular Smooth Muscle and Endothelial Cells: Functional Implications in Angiogenesis, Atherosclerosis, and In-Stent Restenosis. Advances in Experimental Medicine and Biology, 887, 53-77. https://doi.org/10.1007/978-3-319-22380-3_4
|
[62]
|
Kuehbacher, A., Urbich, C., Zeiher, A.M. and Dimmeler, S. (2007) Role of Dicer and Drosha for Endothelial microRNA Expression and Angiogenesis. Circulation Research, 101, 59-68. https://doi.org/10.1161/CIRCRESAHA.107.153916
|
[63]
|
Suarez, Y., Fernandez-Hernando, C., Pober, J.S. and Sessa, W.C. (2007) Dicer Dependent microRNAs Regulate Gene Expression and Functions in Human Endothelial cells. Circulation Research, 100, 1164-1173. https://doi.org/10.1161/01.RES.0000265065.26744.17
|
[64]
|
Otsuka, M., Zheng, M., Hayashi, M., Lee, J.D., Yoshino, O., Lin, S., et al. (2008) Impaired microRNA Processing Causes Corpus Luteum Insufficiency and Infertility in Mice. Journal of Clinical Investigation, 118, 1944-1954. https://doi.org/10.1172/JCI33680
|
[65]
|
Frangogiannis, N.G. (2012) Matricellular Proteins in Cardiac Adaptation and Disease. Physiological Reviews, 92, 635-688. https://doi.org/10.1152/physrev.00008.2011
|
[66]
|
Gonzalez-Quesada, C., Cavalera, M., Biernacka, A., Kong, P., Lee, D.W., Saxena, A., et al. (2013) Thrombospondin-1 Induction in the Diabetic Myocardium Stabilizes the Cardiac Matrix in Addition to Promoting Vascular Rarefaction through Angiopoietin-2 Upregulation. Circulation Research, 113, 1331-1344. https://doi.org/10.1161/CIRCRESAHA.113.302593
|