Prof. Jianxun (Jim) Song

College of Medicine

Texas A&M University, USA

Email: songjianxun@yahoo.com (preferred), jus35@tamu.edu

Qualifications

2001 Ph.D., The Third Military Medical University, China

1993 M.Sc., The Third Military Medical University, China

1989 B.Sc., Chongqing University, China

Publications (Selected)

1. Kumar, A., Das, J. K., Peng, H. Y., Wang, L., Ballard, D. J., Ren, Y., ... & Song, J. (2025). Metabolic fitness of NAC1-deficient Tregs in the tumor microenvironment fuels tumor growth. JCI insight, 10(4), e186000.
2. Thomas, C. J., Delgado, K., Sawant, K., Roy, J., Gupta, U., Song, C. S., ... & Song, J. (2024). Harnessing Bacterial Agents to Modulate the Tumor Microenvironment and Enhance Cancer Immunotherapy. Cancers, 16(22), 3810.
3. Ngule, C., Shi, R., Ren, X., Jia, H., Oyelami, F., Li, D., ... & Yang, J. M. (2024). NAC1 promotes stemness and regulates myeloid-derived cell status in triple-negative breast cancer. Molecular cancer, 23(1), 188.
4. Cabello, A. L., Wells, K., Peng, W., Feng, H. Q., Wang, J., Meyer, D. F., ... & de Figueiredo, P. (2024). Brucella-driven host N-glycome remodeling controls infection. Cell Host & Microbe, 32(4), 588-605.
5. Xu, Y., Sun, F., Tian, Y., Zeng, G., Lei, G., Bai, Z., ... & Liu, R. (2024). Enhanced NK cell activation via eEF2K-mediated potentiation of the cGAS–STING pathway in hepatocellular carcinoma. International Immunopharmacology, 129, 111628.
6. Peng, H. Y., Wang, L., Das, J. K., Kumar, A., Ballard, D. J., Ren, Y., ... & Song, J. (2023). Control of CD4+ T cells to restrain inflammatory diseases via eukaryotic elongation factor 2 kinase. Signal Transduction and Targeted Therapy, 8(1), 415.
7. Wang, L., Peng, H. Y., Kishore Das, J., Kumar, A., Ren, Y., Ballard, D. J., ... & Song, J. (2023). NAC1 confines virus‐specific memory formation of CD4+ T cells through the ROCK1‐mediated pathway. Journal of medical virology, 95(7), e28957.
8. Ngule, C. M., Hemati, H., Ren, X., Obaleye, O., Akinyemi, A. O., Oyelami, F. F., ... & Yang, J. M. (2023). Identification of a NACC1-regulated gene signature implicated in the features of triple-negative breast cancer. Biomedicines, 11(4), 1223.
9. Wang, L., Peng, H. Y., Pham, A., Villazana, E., Ballard, D. J., Das, J. K., ... & Song, J. (2023). T cell response to SARS-CoV-2 coinfection and comorbidities. Pathogens, 12(2), 321.
10. Ren, Y., Kumar, A., Das, J. K., Peng, H. Y., Wang, L., Balllard, D., ... & Song, J. (2022). Tumorous expression of NAC1 restrains antitumor immunity through the LDHA-mediated immune evasion. Journal for Immunotherapy of Cancer, 10(9), e004856.
11. Wang, L., Kumar, A., Das, J. K., Ren, Y., Peng, H. Y., Ballard, D. J., ... & Song, J. (2022). Expression of NAC1 restrains the memory formation of CD8+ T cells during viral infection. Viruses, 14(8), 1713.
12. Yang, J. M., Ren, Y., Kumar, A., Xiong, X., Das, J. K., Peng, H. Y., ... & Song, J. (2022). NAC1 modulates autoimmunity by suppressing regulatory T cell–mediated tolerance. Science Advances, 8(26), eabo0183.
13. Deng, Z., Tian, Y., Song, J., An, G., & Yang, P. (2022). mRNA vaccines: the dawn of a new era of cancer immunotherapy. Frontiers in Immunology, 13, 887125.
14. Chen, X., Wang, K., Jiang, S., Sun, H., Che, X., Zhang, M., ... & Cheng, Y. (2022). eEF2K promotes PD-L1 stabilization through inactivating GSK3β in melanoma. Journal for Immunotherapy of Cancer, 10(3), e004026.
15. Guo, F., Das, J. K., Kobayashi, K. S., Qin, Q. M., Ficht, T. A., Alaniz, R. C., ... & De Figueiredo, P. (2022). Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment. Journal for immunotherapy of cancer, 10(1), e003760.
16. Ballard, D. J., Peng, H. Y., Das, J. K., Kumar, A., Wang, L., Ren, Y., ... & Song, J. (2021). Insights into the pathologic roles and regulation of eukaryotic elongation factor-2 kinase. Frontiers in molecular biosciences, 8, 727863.
17. Wang, L., Das, J. K., Kumar, A., Peng, H. Y., Ren, Y., Xiong, X., ... & Song, J. (2021). Autophagy in T‐cell differentiation, survival and memory. Immunology and Cell Biology, 99(4), 351-360.

Profile Details

WoS ResearcherID: A-8089-2009

https://orcid.org/0000-0002-9734-6176

https://medicine.tamu.edu/faculty-listings/song.htm

https://scholar.google.com/citations?user=rquSjvcAAAAJ&hl=en

https://www.researchgate.net/lab/Jianxun-Song-Lab