Prof. Nelson Leung-Sang TANG
Department of Chemical Pathology
The Chinese University of Hong Kong
Professor
Email: nlstang2014@gmail.com
Qualifications
2002 Doctor of Medicine (CUHK)
1998 Accredited Clinical Biochemists
1997 Fellow of the Royal College of Pathologists of Australasia
1997 Fellow of the Hong Kong Society of Clinical Chemistry
Publications (Selected)
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Huang, J., Chow, A. C., Tang, N. L., & Yam, S. C. P. (2025). An in‐depth benchmark framework for evaluating single cell RNA‐seq dropout imputation methods and the development of an improved algorithm afMF. Clinical and Translational Medicine, 15(4), e70283.
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Huang, J., Yam, P. S., & Tang, N. L. (2025). ‘Trans-differentiation of neutrophils from plasmablast’is an artefact caused by over-reliance on machine algorithms in single cell RNA sequencing analysis: Lesson learnt and steps ahead. bioRxiv, 2025-02.
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Huang, J., Yam, P. S. C., Leung, K. S., Deng, M., & Tang, N. L. S. (2025). Compositional data modeling of high-dimensional single cell RNA-seq (CoDA-hd): its advantages over commonly used normalization approaches. bioRxiv, 2025-03.
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Huang, B., Huang, J., Chiang, N. H., Chen, Z., Lui, G., Ling, L., ... & Tang, N. L. S. (2024). Interferon response and profiling of interferon response genes in peripheral blood of vaccine-naive COVID-19 patients. Frontiers in Immunology, 14, 1315602.
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Yeung, S. S., Ma, S. L., Wang, X., Chen, Y., Tsui, S. K. W., Tang, N. L. S., & Woo, J. (2023). Telomere length among Chinese aged 75+ years. Gerontology, 69(12), 1414-1423.
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Tam, C. H., Lim, C. K., Luk, A. O., Shi, M., Man Cheung, H., Ng, A. C., ... & Ma, R. C. (2023). Identification of a common variant for coronary heart disease at PDE1A contributes to individualized treatment goals and risk stratification of cardiovascular complications in Chinese patients with type 2 diabetes. Diabetes Care, 46(6), 1271-1281.
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Xiao, F. H., Wang, H. T., Chen, X. Q., Ge, M. X., Yan, D., Yang, X. L., ... & Kong, Q. P. (2023). Hypermethylation in H3K9me3 regions characterizes the centenarian methylomes in healthy aging. National Science Review, 10(6), nwad067.
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Jin, Q., Luk, A. O., Lau, E. S., Tam, C. H., Ozaki, R., Lim, C. K., ... & Lee, Y. M. (2022). Nonalbuminuric diabetic kidney disease and risk of all-cause mortality and cardiovascular and kidney outcomes in type 2 diabetes: findings from the Hong Kong Diabetes Biobank. American Journal of Kidney Diseases, 80(2), 196-206.
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Jiang, G., Luk, A. O., Tam, C. H., Ozaki, R., Lim, C. K., Chow, E. Y., ... & Hong Kong Diabetes Biobank Study Group:. (2022). Clinical predictors and long-term impact of acute kidney injury on progression of diabetic kidney disease in Chinese patients with type 2 diabetes. Diabetes, 71(3), 520-529.
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Tam, C. H., Lim, C. K., Luk, A. O., Ng, A. C., Lee, H. M., Jiang, G., ... & Hong Kong Diabetes Biobank Study Group. (2021). Development of genome-wide polygenic risk scores for lipid traits and clinical applications for dyslipidemia, subclinical atherosclerosis, and diabetes cardiovascular complications among East Asians. Genome medicine, 13, 1-18.
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van de Stadt, S. I., Mooyer, P. A., Dijkstra, I. M., Dekker, C. J., Vats, D., Vera, M., ... & Ferdinandusse, S. (2021). Biochemical studies in fibroblasts to interpret variants of unknown significance in the ABCD1 gene. Genes, 12(12), 1930.
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Xu, L., Feng, Z., Dai, Z., Lee, W. Y., Wu, Z., Liu, Z., ... & Zhu, Z. (2021). A functional SNP in the promoter of LBX1 is associated with the development of adolescent idiopathic scoliosis through involvement in the myogenesis of paraspinal muscles. Frontiers in Cell and Developmental Biology, 9, 777890.
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Yang, S., Gong, Z., Liu, Z., Wei, M., Xue, L., Vlantis, A. C., ... & Chen, G. G. (2021). Differential effects of estrogen receptor alpha and beta on endogenous ligands of peroxisome proliferator-activated receptor gamma in papillary thyroid cancer. Frontiers in Endocrinology, 12, 708248.
Profile Details
https://orcid.org/0000-0002-3607-5819
https://www.cuhk.edu.hk/med/cpy/Research/NelsonTang.htm
https://scholar.google.com/citations?user=nBtfmp8AAAAJ&hl=en
https://www.researchgate.net/profile/Nelson-Tang-3