[1]
|
Spahn, L., Siligan, C., Bachmaier, R., Schmid, J.A., Aryee, D.A.T. and Kovar, H. (2003) Homotypic and heterotypic interactions of EWS, Fli-1 and their oncogenic fusion proteins. Oncogene, 22, 6819-6829.
doi:10.1038/sj.onc.1206810
|
[2]
|
Ng, K.P., Potikyan, G., Savene, R.O.V., Denny, C.T., Uversky, V.N. and Lee, K.A.W. (2007) Multiple aromatic side chains within a disordere structure are critical for transcription and transforming activity of EWS family oncoproteins. PNAS, 104, 479-484.
doi:10.1073/pnas.0607007104
|
[3]
|
Dosztanyi, Z., Csizmok, V., Tompa, P. and Simon, I. (2005) IUPred: Web server for the prediction of intrinsically unstructured regions of proteins based on estimated energy content. Bioinformatics, 21, 3433-3434.
doi:10.1093/bioinformatics/bti541
|
[4]
|
Linding, R., Russell, R.B., Neduva, V. and Gibson, T.J. (2003) GlobPlot: Exploring protein sequences for globularity and disorder. Nucleic Acids Research, 31, 3701- 3708. doi:10.1093/nar/gkg519
|
[5]
|
Linding, R., Jensen, L.J., Diella, F., Bork, P., Gibson, T.J. and Russell, R.B. (2003) Protein disorder prediction: Implications for structural proteomics. Structure, 11, 1453- 1459. doi:10.1016/j.str.2003.10.002
|
[6]
|
Prilusky, J., Felder, C.E., Zeev-Ben-Mordehai, T., Rydberg, E.H., Man, O., Beckmann, J.S., Silman, I., Sussman, J.L. (2005) FoldIndex: A simple tool to predict whether a given protein sequence is intrinsically unfolded. Bioinformatics, 21, 3435-3438.
doi:10.1093/bioinformatics/bti537
|
[7]
|
Yang, Z.R., Thomson, R., McNeil, P. and Esnouf, R.M. (2005) RONN: The bio-basis function neural network technique applied to the detection of natively disordered regions in proteins. Bioinformatics, 21, 3369-3376.
doi:10.1093/bioinformatics/bti534
|
[8]
|
Xue, B., Dunbrack, R.L., Williams, R.W., Dunker, A.K. and Uversky, V.N. (2010) PONDR-FIT: A meta-predictor of intrinsically disordered amino acids. Biochim Biophys Acta, 1804, 996-1010.
|
[9]
|
Obradovic, Z., Peng, K., Vucetic, S., Radivojac, P., Brown, C.J. and Dunker, A.K. (2003) Predicting intrinsic disorder from amino acid sequence. Proteins, 53, 566-572.
doi:10.1002/prot.10532
|
[10]
|
Uversky, V.N., Oldfield, C.J., Midic, U., Xie, H., Xue, B., Vucetic, S., Iakoucheva, L.M., Obradovic, Z. and Dunker, A.K. (2009) Unfoldomics of human diseases: Linking protein intrinsic disorder with diseases. BMC Genomics, 10, S7. doi:10.1186/1471-2164-10-S1-S7
|
[11]
|
Liu, J., Perumal, N.B., Oldfield, C.J., Su, E.W., Uversky, V.N. and Dunker, A.K. (2006) Intrinsic disorder in transcription factors. Biochemistry, 45, 6873-6888.
doi:10.1021/bi0602718
|
[12]
|
Hegyi, H., Buday, L. and Tompa, P. (2009) Intrinsic Structural Disorder Confers Cellular Viability on Oncogenic Fusion Proteins. PLoS Computational Biology, 5, e1000552. doi:10.1021/bi0602718
|
[13]
|
Pan, S., Ming, K.Y., Dunn, T.A., Li, K.K. and Lee, K.A. (1998) The EWS/ATF1 fusion protein contains a dispersed activation domain that functions directly. Oncogene, 16, 1625-1631.
doi:10.1038/sj.onc.1201671
|
[14]
|
Heyerdahl, S.L., Rozenberg, J., Jamtgaard, L., Rishi, V., Varticovski, L., Akah, K., Scudiero, D., Shoemaker, R.H., Karpova, T.S., Day, R.N., McNally, J.G. and Vinson, C. (2010) The arylstibonic acid compound NSC13746 disrupts B-ZIP binding to DNA in living cells. European Journal of Cell Biology, 89, 564-573.
doi:10.1016/j.ejcb.2009.11.029
|
[15]
|
Bertolotti, A., Melot, T., Acker, J., Vigneron, M., Dellatre, O. and Tora, L. (1998) EWS, but not EWS-Fli-1, is associated with both TFIID and RNA-polymerase II: Interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA Polymerase II complexes. Molecular Cell Biology, 18, 1489-1497.
|
[16]
|
Uren, A., Tcherkasskaya, O. and Toretsky, J.A. (2004) Recombinant EWS-FLI1 oncoprotein activates transcription. Biochemistry, 42, 13579-13589.
doi:10.1021/bi048776q
|
[17]
|
Kim, J., Lee, J.M., Branton, P.E. and Pelletier, J. (1999) Modification of EWS/WT1 functional properties by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America, 96, 14300- 14305. doi.org/10.1073/pnas.96.25.14300
|
[18]
|
Butticè, G., Duterque-Coquillaud, M., Basuyaux, J.P., Carrère, S., Kurkinen, M. and Stéhelin, D. (1996) Erg, an Ets-family member, differentially regulates human collagenase1 (MMP1) and stromelysin1 (MMP3) gene expression by physically interacting with the Fos/Jun complex. Oncogene, 13, 2297-2306.
|
[19]
|
Basuyaux, J.P., Ferreira, E., Stéhelin, D. and Butticè, G. (1997) The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner. Journal of Biological Chemistry, 272, 26188- 26195. doi.org/10.1074/jbc.272.42.26188
|
[20]
|
Lee, K.A. (2007) Ewings family oncoproteins: drunk, disorderly and in search of partners. Cell Research, 17, 286-288. doi:10.1038/cr.2007.22
|
[21]
|
Taggart, A.K. and Pugh, B.F. (1996) Dimerization of TFIID when not bound to DNA. Science, 272, 1331-1333.
doi:10.1126/science.272.5266.1331
|
[22]
|
Carrère, S., Verger, A., Flourens, A., Stehelin, D. and Duterque-Coquillaud, M. (1998) Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains. Oncogene, 16, 3261-3268.
doi:10.1038/sj.onc.1201868
|
[23]
|
Todorova, R. (2009) In vitro interaction between the N-terminus of the Ewing’s sarcoma protein and the subunit of RNA polymerase II hsRPB7. Molecular Biology Reports, 36, 1269-1274.
doi:10.1007/s11033-008-9308-2
|
[24]
|
Erkizan, H.V., Kong, Y., Merchant, M., Schlottmann, S., Barber-Rotenberg, J.S., Yuan, L., Abaan, O.D., Chou, T.-H., Dakshanamurthy, S., Brown, M.L., Uren, A. and Toretsky, J.A. (2009) A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing’s sarcoma. Nature Medicine, 15, 750-757. doi:10.1038/nm.1983
|