Targeted temperature management (TTM), previously known as therapeutic hypothermia or protective hypothermia, is an active treatment that tries to achieve and maintain a specific body temperature in a person for a specific duration of time in an effort to improve health outcomes during recovery after a period of stopped blood flow to the brain. This is done in an attempt to reduce the risk of tissue injury following lack of blood flow. Periods of poor blood flow may be due to cardiac arrest or the blockage of an artery by a clot as in the case of a stroke. 

In the present book, fifteen typical literatures about Targeted temperature management published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on Targeted temperature management. We hope this book can demonstrate advances in Targeted temperature management as well as give references to the researchers, students and other related people.