Advances in Single-Cell Secretion Analysis
Secretion is the movement of material from one point to another, such as a secreted chemical substance from a cell or gland. In contrast, excretion is the removal of certain substances or waste products from a cell or organism. The classical mechanism of cell secretion is via secretory portals at the plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures embedded in the cell membrane, where secretory vesicles transiently dock and fuse to release intra-vesicular contents from the cell.
In the present book, ten typical literatures about Single-cell secretion research published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on Single-cell secretion research. We hope this book can demonstrate advances in Single-cell secretion research as well as give references to the researchers, students and other related people.
Sample Chapter(s)
Preface (44 KB)
Components of the Book:
  • Chapter 1 A cell-penetrating bispeciffc antibody suppresses hepatitis B virus replication and secretion
  • Chapter 2 Beta cell speciffc ZnT8 gene deffciency and resulting loss in zinc content signiffcantly improve insulin secretion
  • Chapter 3 Betagenin ameliorates diabetes by inducing insulin secretion and b-cell proliferation
  • Chapter 4 Dopamine-mediated autocrine inhibition of insulin secretion
  • Chapter 5 Identiffcation of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies
  • Chapter 6 Impaired ApoB secretion triggers enhanced secretion of ApoE to maintain triglyceride homeostasis in hepatoma cells
  • Chapter 7 Insights into the relationship between persistent antibody secretion and metabolic programming–A question for single-cell analysis
  • Chapter 8 Quantitative live-cell imaging of secretion activity reveals dynamic immune responses
  • Chapter 9 Screening and selection of cellulase-secreting yeast single cells using integrated double emulsion droplet and flow cytometry techniques
  • Chapter 10 Tacrolimus regulates extracellular vesicle secretion from T cells via autophagy-lysosomal pathway
Readership: Students, academics, teachers and other people attending or interested in Single-Cell Secretion Analysis
Hangrui Liu

Jonathan V. Rocheleau

Anthony Piro

and more...
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