Synthesis and Antimicrobial Activity of a New Class of Sulfone Linked Bisheterocycles

Venkatapuram Padmavathi, Thunga Radha Lakshmi, Bhumireddy Chinnachennaiahgari Venkatesh, Konda Mahesh

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DOI: 10.4236/ijoc.2011.13013                

Abstract

A new and novel class of bis(heterocycles) viz., bis pyrroles, pyrrolyl pyrazoles and pyrrolyl isoxazoles are prepared from 1-aroyl-2-styrylsulfonylethenes by 1,3-dipolar cycloaddition of tosylmethyl isocyanide, diazomethane, nitrile imines and nitrile oxides. The lead compounds are screened for antimicrobial activity.

Keywords

1-Aroyl-2-Styrylsulfonylethene, 1, 3-Dipolar Cycloaddition, Chloramine-T, Antimicrobial Activity

Conflicts of Interest

The authors declare no conflicts of interest.

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