Author(s)

A. Coulibaly^1*, A. K. Sermé¹, H. Godonou¹, K. S. Somda¹, K. Cissé¹, Sia Romond², Kafando Roch³, R. A. Sombié¹, A. Bougouma¹

¹Gastroenterology Service of the University Hospital Centre Yalgado Ouédraogo (CHUYO), Ouagadougou, Burkina Faso.
²Schipphra Medical Center, Ouagadougou, Burkina Faso.
³Surgery of CHUYO, Ouagadougou, Burkina Faso.

Background: Prevalence of Peptic Ulcer Disease (PUD) is decreasing in developed countries since the use of the treatments for eradication of Helicobacter pylori. Objectives: To revalue the sociodemographic, clinical and evolutionary aspects of the PUD among hospitalized patients in CHUYO. Methodology: This prospective study is related to 65 files of patients hospitalized in hepato-gastroenterology and general surgical services of the CHUYO between March 1st and August 31st, 2015. Results: Hospital utilization rate was 6.59%. The average age of patients was 40.6 years with extremes of 17 and 80 years. The sex ratio was 9.8. The location of the ulcer was 69.23% in stomach. A notion of taking aggressive gastrointestinal products was found in 62 patients (95.4%). The clinical picture was represented by diffuse abdominal pain (76.92%), peritoneal irritation syndrome (64.61%) and epigastric pain (56.92%), anemia (23.07%). Gastric perforations (64.61%) and gastrointestinal bleeding (12.30%) were the main complications. Consumption of non-steroidal anti-inflammatory drugs (NSAIDs) was found in 81.5% of cases. The management was medical and/or surgical with an overall mortality rate of 7.7%. Conclusion: The PUD rate decreased from 10.12% to 6.59% in 5 years. The complications are dominated by stomach perforations. They are relative increase and seem related to NSAIDs. Better management of this disease requires awareness of the population to self-medication.

Peptic Ulcer Disease, Helicobacter pylori, Bleeding Perforation

Coulibaly, A. , Sermé, A. , Godonou, H. , Somda, K. , Cissé, K. , Romond, S. , Roch, K. , Sombié, R. and Bougouma, A. (2016) Peptic Ulcer Disease in CHUYO. Open Journal of Gastroenterology, 6, 353-361. doi: 10.4236/ojgas.2016.611038.