Geriatric Nutritional Risk Index as a Simple Predictor of Mortality in Maintenance Hemodialysis Patients: A Single Center Study - International Journal of Clinical Medicine

IJCM > Vol.6 No.5, May 2015

Geriatric Nutritional Risk Index as a Simple Predictor of Mortality in Maintenance Hemodialysis Patients: A Single Center Study ()

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DOI: 10.4236/ijcm.2015.65046 3,618 Downloads 4,950 Views Citations

Author(s)

Sayaka Takahashi¹, Keiko Suzuki¹, Fumiko Kojima¹, Yoshiko Tanaka¹, Kosaku Nitta^2*

Affiliation(s)

¹Department of Nephrology, Shinjuku Ishikawa Clinic.
²Department of Medicine, Kidney Center, Tokyo Women’s Medical University, Tokyo, Japan.

ABSTRACT

Background: Malnutrition is associated with higher risk of mortality in maintenance hemodialysis (MHD) patients. The geriatric nutritional risk index (GNRI) has been developed as a tool to assess the nutritional risk. Objectives: The purpose of the present study was to examine the significance of the GNRI as a mortality predictor in MHD patients. Methods: We retrospectively examined the GNRI of 259 MHD patients aged 59.2 ± 12.8 years, and followed up for 36 months. The patients were divided into two groups according to GNRI values of 91.0. Predictors for all-cause mortality were examined using Kaplan-Meier and Cox proportional-hazards analyses. Results: During the follow-up period of 36 months, a total of 76 patients died. Kaplan-Meier survival analysis showed that the subjects with a GNRI < 91 (n = 29) had a lower survival rate than those with a GNRI > 91 (n = 230) (Log-rank test, p < 0.0001). Multivariate Cox proportional-hazards analysis demonstrated that the GNRI was a significant predictor of adjusted all-cause mortality (hazard ratio 0.927; confidence interval 0.870 - 0.984, p = 0.013). Conclusion: The results of the present study demonstrate that the GNRI is a strong predictor of all-cause mortality in MHD patients.

KEYWORDS

Hemodialysis, Malnutrition, Geriatric Nutritional Risk Index, Mortality

Share and Cite:

Takahashi, S. , Suzuki, K. , Kojima, F. , Tanaka, Y. and Nitta, K. (2015) Geriatric Nutritional Risk Index as a Simple Predictor of Mortality in Maintenance Hemodialysis Patients: A Single Center Study. International Journal of Clinical Medicine, 6, 354-362. doi: 10.4236/ijcm.2015.65046.

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