Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China - International Journal of Clinical Medicine

IJCM > Vol.4 No.7, July 2013

Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China ()

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DOI: 10.4236/ijcm.2013.47057 4,011 Downloads 6,042 Views Citations

Author(s)

Guohong Tian, Lin Sun, Yunhong He, Xiaojun Zhang

Affiliation(s)

Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China..
Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China;.

ABSTRACT

Creutzfeldt-Jakob disease (CJD) is a rare but fatal neurodegenerative prion disease. Classic CJD comprises a clinical triad of rapidly progressive dementia, myoclonus, and EEG abnormality. At initial presentation, this classic triad is present only in a minority of cases. Visual impairment is one of the predominant manifestations in the course of CJD, especially in Heidenhain variant phenotype. We reported a case presenting with progressive blurred vision, along with other neurological symptoms, who diagnosed as sporadic CJD with cortical blindness in China.

KEYWORDS

Creutzfeldt-Jakob Disease; Visual Disturbance; Heidenhain Variant; Diffusion Weighted Imaging

Share and Cite:

G. Tian, L. Sun, Y. He and X. Zhang, "Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China," International Journal of Clinical Medicine, Vol. 4 No. 7, 2013, pp. 321-324. doi: 10.4236/ijcm.2013.47057.

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