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Role of Apoptosis in Microbial Infection

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DOI: 10.4236/ojapo.2014.32004    4,503 Downloads   7,621 Views  


Apoptosis plays a central role in the pathogenesis of a number of human diseases. Because apoptosis represents a fundamental process in the response to such infections, it may represent a therapeutic target for their treatment. There is thus likely to be future clinical relevance in harnessing our growing knowledge both of apoptotic mechanisms, and their regulation, in the search to achieve modalities for therapeutic benefit. This brief review aims to summarize what we currently know about the role of apoptosis in response to a range of microbial infections (including bacterial and viral).

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The authors declare no conflicts of interest.

Cite this paper

Alenzi, F. , Alotaibi, A. , Almotiri, G. , Alanazi, A. , Alanazi, F. , Alenazi, M. , Alanazi, K. , Alenzi, M. and Ahmad, S. (2014) Role of Apoptosis in Microbial Infection. Open Journal of Apoptosis, 3, 32-38. doi: 10.4236/ojapo.2014.32004.


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