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Quantification of Solid Residues by Raman Spectroscopy

DOI: 10.4236/opj.2013.35A001    3,082 Downloads   5,159 Views  


We suggest a mathematical route which has the capability to obtain quantitative information of solid residues on a substrate of aluminum, in which the evaporation of the deposited micro-drops has the form of coffee rings. In this job, the glycine aminoacid was used as probe molecule. We suppose that the number of moles present on the study sample is proportional to the Raman signal and to the experimental parameters of the used Raman system. Then, the mass and the number of molecules can be determined with these data. We showed that the mathematical expression is simple and elegant for its implementation. On the other hand, we have applied and demonstrated that the technique of principal component analysis (PCA) can be used to obtain quantitative information of the sample. Our results show quantitative analysis of glycine residues between 10-11 to 10-15 g.

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The authors declare no conflicts of interest.

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E. Araiza-Reyna, R. Sato-Berrú and A. Vázquez-Olmos, "Quantification of Solid Residues by Raman Spectroscopy," Optics and Photonics Journal, Vol. 3 No. 5A, 2013, pp. 1-6. doi: 10.4236/opj.2013.35A001.


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