Uremia is the term for high levels of urea in the blood. Urea is one of the primary components of urine. It can be defined as an excess of amino acid and protein metabolism end products, such as urea and creatinine, in the blood that would be normally excreted in the urine. Uremic syndrome can be defined as the terminal clinical manifestation of kidney failure (also called renal failure). It is the signs, symptoms and results from laboratory tests which result from inadequate excretory, regulatory, and endocrine function of the kidneys. Both uremia and uremic syndrome have been used interchangeably to denote a very high plasma urea concentration that is the result of renal failure. The former denotation will be used for the rest of the article.
Sample Chapter(s)
Preface (48 KB)
Components of the Book:
- Chapter1
Uremia does not affect neointima formation in mice
- Chapter2
Identifying prognostic factors of severe metabolic acidosis and uraemia in African children with severe falciparum malaria: a secondary analysis of a randomized trial
- Chapter3
A Novel Mouse Model of Peritoneal Dialysis: Combination of Uraemia and Long-Term Exposure to PD Fluid
- Chapter4
Uremia increases QRS duration after β‐adrenergic stimulation in mice
- Chapter5
Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia
- Chapter6
ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model
- Chapter7
Renal function, uraemia and early arteriovenous fistula failure
- Chapter8
Co-Expression Analysis of Blood Cell Genome Expression to Preliminary Investigation of Regulatory Mechanisms in Uremia
- Chapter9
Resveratrol Reduces Kidney Injury in a Rat Model of Uremia and is Associated with Increased Expression of Heat Shock Protein 70 (Hsp70)
- Chapter10
Aging and uremia: Is there cellular and molecular crossover?
- Chapter11
Thrombotic Role of Blood and Endothelial Cells in Uremia through Phosphatidylserine Exposure and Microparticle Release
- Chapter12
Increased Neutrophil Extracellular Trap Formation in Uremia Is Associated with Chronic Inflammation and Prevalent Coronary Artery Disease
- Chapter13
Coagulation activation, depletion of platelet granules and endothelial integrity in case of uraemia and haemodialysis treatment
- Chapter14
Coagulation activation, depletion of platelet granules and endothelial integrity in case of uraemia and haemodialysis treatment
- Chapter15
Conformational Changes of Blood ACE in Chronic Uremia
Readership:
Students, academics, teachers and other people attending or interested in Uremia
Annemarie Aarup
Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark
Carsten H. Nielsen
Department of Clinical Physiology, Nuclear Medicine & PET and Cluster for Molecular Imaging, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Ilze Bot
Division of Biopharmaceutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands
Lars B. Nielsen
Copenhagen University Hospital, Rigshospitalet, Department of Clinical Biochemistry, Copenhagen, Denmark
and more...