Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. In an adult, CBF is typically 750 millilitres per minute or 15% of the cardiac output. This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. CBF is tightly regulated to meet the brain's metabolic demands. Too much blood (a clinical condition of a normal homeostatic response of hyperemia) can raise intracranial pressure (ICP), which can compress and damage delicate brain tissue. Too little blood flow (ischemia) results if blood flow to the brain is below 18 to 20 ml per 100 g per minute, and tissue death occurs if flow dips below 8 to 10 ml per 100 g per minute. In brain tissue, a biochemical cascade known as the ischemic cascade is triggered when the tissue becomes ischemic, potentially resulting in damage to and the death of brain cells. Medical professionals must take steps to maintain proper CBF in patients who have conditions like shock, stroke, cerebral edema, and traumatic brain injury.
Components of the Book:
- Chapter 1
Cerebral Blood Flow Decrease as an Early Pathological Mechanism in Alzheimer’S Disease
- Chapter 2
Regional Cerebral Blood Flow as Predictor of Response to Occipital Nerve Block in Cluster Headache
- Chapter 3
Inverse Correlation of Fluctuations of Cerebral Blood and Water Concentrations in Humans
- Chapter 4
Glucagon‑Like Peptide‑1 (Glp‑1) Receptor Activation Dilates Cerebral Arterioles, Increases Cerebral Blood Flow, And Mediates Remote (Pre) Conditioning Neuroprotection Against Ischaemic Stroke
- Chapter 5
The Relationship Between Cerebral Blood Flow And Venous Sinus Pressure: Can Hyperemia Induce Idiopathic Intracranial Hypertension?
- Chapter 6
Genetic Enhancement of Microsomal Epoxide Hydrolase Improves Metabolic Detoxification But Impairs Cerebral Blood Flow Regulation
- Chapter 7
Cortical Cerebral Blood Flow in Ageing: Effects of Haematocrit, Sex, Ethnicity and Diabetes
- Chapter 8
Effects of Hypoglycaemia on Working Memory and Regional Cerebral Blood Flow in Type 1 Diabetes: A Randomised, Crossover Trial
- Chapter 9
A Pilot Study Exploring the Effect of Repetitive Transcranial Magnetic Stimulation (Rtms) Treatment on Cerebral Blood Flow and Its Relation to Clinical Outcomes in Severe Enduring Anorexia Nervosa
- Chapter 10
Temporal and Spatial Changes in Cerebral Blood Flow in Neuropsychiatric Systemic Lupus Erythematosus: A Subtraction Brain Spect Study
- Chapter 11
Temporal Dynamics Of Cerebral Blood Flow During The Acute Course Of Severe Subarachnoid Hemorrhage Studied By Bedside Xenon‑Enhanced Ct
- Chapter 12
Synthesis And Evaluation Of N‑Isopropyl‑P‑[11c]Methylamphetamine as A Novel Cerebral Blood Flow Tracer For Positron Emission Tomography
- Chapter 13
Tau Pathology and Relative Cerebral Blood Flow Are Independently Associated with Cognition in Alzheimer’S Disease
- Chapter 14
Blood Flow Response to Orthostatic Challenge Identifies Signatures of The Failure Of Static Cerebral Autoregulation in Patients With Cerebrovascular Disease
- Chapter 15
Multivitamins and Minerals Modulate Whole-Body Energy Metabolism and Cerebral Blood-Flow during Cognitive Task Performance: A Double-Blind, Randomised, Placebo-Controlled Trial
Readership:
Students, academics, teachers and other people attending or interested in Cerebral Blood Flow.
Nils Korte
Department of Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
Tara Renton
Busch V et al (2007) Occipital nerve blockade in chronic cluster headache patients and functional connectivity between trigeminal and occipital nerves. Cephalalgia 27(11):1206–1214
Viola Borchardt
Oulu Functional Neuroimaging Group, Research Unit of Medical Imaging Physics and Technology (MIPT), University of Oulu, Oulu, Finland
Shereen Nizari
Centre for Cardiovascular and Metabolic Neuroscience, Neuroscience, Physiology and Pharmacology, University College London, Gower Street, London WC1E 6BT, UK
Tracie Barber
School of Mechanical Engineering, University of New South Wales, Library Rd, Kensington, NSW 2052, Australia
and more...