Advances in Osteoporosis

Osteoporosis is a disease where decreased bone strength increases the risk of a broken bone. It is the most common reason for a broken bone among the elderly. Osteoporosis may be due to lower than normal peak bone mass and greater than normal bone loss. Bone loss increases after menopause due to lower levels of estrogen. Osteoporosis may also occur due to a number of diseases or treatments including alcoholism, anorexia, hyperthyroidism, surgical removal of the ovaries, and kidney disease. Certain medications increase the rate of bone loss including some antiseizure medications, chemotherapy, proton pump inhibitors, selective serotonin reuptake inhibitors, and steroids. Not enough exercise and smoking are also risk factors. Osteoporosis is defined as a bone density of 2.5 standard deviations below that of a young adult. This is typically measured by dual-energy X-ray absorptiometry at the hip.


In the present book, fifteen typical literatures about osteoporosis published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on medical science, aging-associated diseases, endocrine diseases, epidemiology, ect. We hope this book can demonstrate advances in osteoporosis as well as give references to the researchers, students and other related people.
Components of the Book:
  • Chapter 1
    Osteoporosis: Are Healthcare Professionals Missing an Opportunity
  • Chapter 2
    Prevalence of Osteoporosis in China: A Meta-Analysis and Systematic Review
  • Chapter 3
    Factors Influencing Diagnosis and Treatment of Osteoporosis after a Fragility Fracture among Postmenopausal Women in Asian Countries: A Retrospective Study
  • Chapter 4
    Lower Circulating Preptin Levels in Male Patients with Osteoporosis Are Correlated With Bone Mineral Density and Bone Formation
  • Chapter 5
    Responsiveness of the Japanese Osteoporosis Quality of Life Questionnaire in Women with Postmenopausal Osteoporosis
  • Chapter 6
    Validation of an Osteoporosis Self-Assessment Tool to Identify Primary Osteoporosis and New Osteoporotic Vertebral Fractures in Postmenopausal Chinese Women in Beijing
  • Chapter 7
    Association between the Awareness of Osteoporosis and the Quality of Care for Bone Health among Korean Women with Osteoporosis
  • Chapter 8
    Association between Gastrointestinal Events and Osteoporosis Treatment Initiation in Women Diagnosed with Osteoporosis in France: A Retrospective Analysis
  • Chapter 9
    Effective Osteoporosis Treatment with Teriparatide Is Associated with Enhanced Quality Of Life in Postmenopausal Women with Osteoporosis: The European Forsteo Observational Study
  • Chapter 10
    Efficacy and Safety of Once-Yearly Zoledronic Acid in Japanese Patients with Primary Osteoporosis: Two-Year Results from a Randomized Placebo-Controlled Double-Blind Study (ZOledroNate Treatment in Efficacy to Osteoporosis; ZONE Study)
  • Chapter 11
    The Reliability of the Arabic Version of Osteoporosis Knowledge Assessment Tool (OKAT) and the Osteoporosis Health Belief Scale (OHBS)
  • Chapter 12
    Disability-Adjusted-Life-Years Losses in Postmenopausal Women with Osteoporosis: A Burden of Illness Study
  • Chapter 13
    Increased Migraine Risk in Osteoporosis Patients: A Nationwide Population‑Based Study
  • Chapter 14
    Patient-Reported Barriers to Osteoporosis Therapy
  • Chapter 15
    Strategies to Overcome Barriers to Implementing Osteoporosis and Fracture Prevention Guidelines in Long-Term Care: A Qualitative Analysis of Action Plans Suggested by Front Line Staff in Ontario, Canada
Readership: Students, academics, teachers and other people attending or interested in Osteoporosis.
Tao Fan, Global Human Health, Outcomes Research, WS2E-76, Merck Sharp and Dohme, One Merck Drive, Whitehouse Station, NJ 08889, USA.

Ning Li, Department of Rheumatology, Shanghai East Hospital, Tong Ji University, Shanghai, China.

Hisashi Urushihara, Division of Drug Development & Regulatory Science, Faculty of Pharmacy, Keio University, Minato-ku, Tokyo, Japan.

Sang Min Park, Department of Family Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

Bernard Cortet, Rheumatology Department, University Hospital of Lille, Lille Cedex, France.

Östen Ljunggren, Division of Endocrinology, Department of Medical Sciences, Uppsala University Hospital, Uppsala S-751 85, Sweden.

and more...
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