Advances of NMR in Biomedical Field

Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a magnetic field absorb and re-emit electromagnetic radiation. This energy is at a specific resonance frequency which depends on the strength of the magnetic field and the magnetic properties of the isotope of the atoms. NMR allows the observation of specific quantum mechanical magnetic properties of the atomic nucleus. Many scientific techniques exploit NMR phenomena to study molecular physics, crystals, and non-crystalline materials through nuclear magnetic resonance spectroscopy. NMR is also routinely used in advanced medical imaging techniques, such as in magnetic resonance imaging (MRI), by which biochemical information can be obtained from living tissue (e.g. human brain tumors) with the technique known as in vivo magnetic resonance spectroscopy or chemical shift NMR Microscopy.

 

In the present book, fifteen typical literatures about NMR in biomedical field published on international authoritative journals were selected to introduce the worldwide newest progress, which contains reviews or original researches on scientific techniques, medical science, biomedical applications, ect. We hope this book can demonstrate advances in NMR in biomedical field as well as give references to the researchers, students and other related people.

Components of the Book:
  • Chapter 1
    Integrative NMR for Biomolecular Research
  • Chapter 2
    NightShift: NMR Shift Inference by General Hybrid Model Training - A Framework for NMR Chemical Shift Prediction
  • Chapter 3
    ASIC‑Based Design of NMR System Health Monitor for Mission/Safety–Critical Applications
  • Chapter 4
    1H-NMR Spectroscopy for Human 3D Neural Stem Cell Cultures Metabolic Profiling
  • Chapter 5
    1H, 23Na and 35Cl Imaging in Cementitious Materials with NMR
  • Chapter 6
    Increasing the Sensitivity of NMR Diffusion Measurements by Paramagnetic Longitudinal Relaxation Enhancement, with Application to Ribosome–Nascent Chain Complexes
  • Chapter 7
    Preparation of Highly and Generally Enriched Mammalian Tissues for Solid State NMR
  • Chapter 8
    Optimization of Protein Samples for NMR Using Thermal Shift Assays
  • Chapter 9
    Arginine‑, D‑Arginine‑Vasopressin, and Their Inverso Analogues in Micellar and Liposomic Models of Cell Membrane: CD, NMR, and Molecular Dynamics Studies
  • Chapter 10
    Ethanol Contamination of Cerebrospinal Fluid during Standardized Sampling and Its Effect on 1H-NMR Metabolomics
  • Chapter 11
    NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib
  • Chapter 12
    NMR Resonance Assignments of the Major Apple Allergen Mal d 1
  • Chapter 13
    The Nitrogen Inversion in Fused Isoxazolidinyl Derivatives of Substituted Uracil: Synthesis, NMR and Computational Analysis
  • Chapter 14
    The Second Round of Critical Assessment of Automated Structure Determination of Proteins by NMR: CASD-NMR-2013
  • Chapter 15
    RESEARCH NOTE: Permeability Control on the Relationship between Nuclear Magnetic Resonance (NMR) Measured Porosity and Routine Core Porosity
Readership: Students, academics, teachers and other people attending or interested in NMR in Biomedical Field
Woonghee Lee
National Magnetic Resonance Facility at Madison and Biochemistry Department, University of Wisconsin-Madison, Madison, USA

P. Balasubramanian
School of Computer Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, Singapore

Sammy H. S. Chan
Institute of Structural and Molecular Biology, University College London and Birkbeck College, London, UK

Veronica Wai Ching Wong
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK

Sandra Kozak
SPC Facility, European Molecular Biology Laboratory (EMBL), Hamburg Outstation, Notkestrasse 85, Hamburg, Germany

Changman Du
National Chengdu Center for Safety Evaluation of Drugs, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, High-tech Development Zone, Chengdu, China

and more...
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