TITLE:
Emergence of New Injectable Lipid Emulsions in the USA: Guidance for Pediatric Clinicians
AUTHORS:
Oscar R. Herrera, Lisa A. Caviness, Richard A. Helms
KEYWORDS:
Lipid Emulsions, Fatty Acids, Parenteral Nutrition, Pediatrics
JOURNAL NAME:
Food and Nutrition Sciences,
Vol.10 No.7,
July
30,
2019
ABSTRACT: With the advent of new, particularly mixed-oil lipid emulsions approved
by the United States Food & Drug Administration (FDA), clinicians have more
options when choosing one as part of the parenteral nutrition support of
patients. Lipid products long-standing availability in Europe and other parts
of the world has certainly facilitated the process in the United States, where
there was little evolution before 2014. These newer oil-based emulsions are finding their way to be used in pediatrics, as studies
are being carried out that will result in
pediatric labeling. Pediatric clinicians may find themselves wondering
how these lipid emulsions are different from those that have come before; whether the same dosing or administration practices
apply as with the traditional soybean-oil lipid emulsion, and if they can be used
for other more emergent interventions. We present this review of the current
lipid emulsions available in the U.S. market, highlighting the differences
among them, as well as, providing some practical information for clinicians
that can assist them in their day-to-day duties.