TITLE:
Comparison of an Intraoperative Application of a Haemostatic Agent (PerClot®) with Conventional Haemostatic Procedure after Thyroid Resection
AUTHORS:
Thomas von Ahnen, Martin von Ahnen, Ulrich Wirth, Anna Barisic, Hans Martin Schardey, Stefan Schopf
KEYWORDS:
Hemostatic Agent, Thyroid Resection, Drainage Volume, Post-Operative Hematoma, PerClot®
JOURNAL NAME:
Surgical Science,
Vol.6 No.6,
June
15,
2015
ABSTRACT: Background: Postoperative hemorrhage remains an
uncommon but potentially life-threatening complication of thyroid surgery. The
aim of this case-controlled study was to compare the effectiveness of PerClot® hemostatic agent with hemostasis by conventional
technique (HCT) in thyroid surgery. Methods: The thyroid resection was
performed from November 2009 to February 2010. Exclusion criteria were applied.
There were 30 patients in the HCT group and 30 patients in the PerClot® group. The outcome
parameters were postoperative bleeding, the drainage volume 24 hours postoperatively
and adverse events according to PerClot®. Results: There was no
post-operative hemorrhage in both groups. We found no significant difference
between the control andPerClot® group with regard to total drainage volume after 24 h (51
ml ± 36.9 control group/53 ml ± 39.5 PerClot® group (p = 0.79)). There were no adverse events in the PerClot® group. Conclusions: Routine
use of PerClot® hemostatic agent has no
advantage over conventional hemostasis technique (HCT) in thyroid surgery. In
addition, PerClot®is safe and well tolerated.