TITLE:
Serological Profile of Viral Hepatitis B at the SOLABGUI Analysis Laboratory from January 1, 2020 to December 31, 2024
AUTHORS:
Diallo Kadiatou, Barry Mamadou Bailo, Diallo Mamadou Sarifou, Diallo Djenabou, Wann Thierno Amadou, Diallo Ahmed Tidiane, Bah Mamadou Lamine Yaya, Illa Hamidine, Sylla Djibril, Tounkara Mamadou Oury, Diallo Abdourahmane N’Djouria
KEYWORDS:
Viral Hepatitis B, Prevalence, Laboratory, Sampling, Conakry University Hospital
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.15 No.2,
May
8,
2025
ABSTRACT: Introduction: viral hepatitis B is a major public health problem. The objective of this study was to determine the prevalence of HBsAgat the laboratory of the Biomedical Analysis Laboratory Society of Guinea (SOLABGUI). Materials and Methods: it was a retrospective descriptive study from January 1, 2020 to December 31, 2024. It concerned all samples for which HBs antigen was requested during the study period at the SOLABGUI laboratory. Results: we listed a total of 2000 bulletins for which HBsAg was requested. We obtained 390 HBsAg positive bulletins, representing a prevalence of 19.5%. Men were the most represented with a frequency of 63.59% (n = 248) with a sex ratio M/F equal to 1.74. The average age of our patients was 22 ± 4 years with extremes of 1 and 80 years. The age group of 31 - 40 years was the most affected with a frequency of 30.77% (n = 120) followed by that over 50 years with a frequency of 23.85% (n = 93) and that of 21 - 30 years with a frequency of 17.69% (n = 69). Merchants and civil servants were the most represented with an identical frequency of 18.46% (n = 72). Married people were the most affected with a frequency of 59.49% (n = 232), single people 40.51% (n = 158). HBV co-infections with HIV and HCV were 2.22% and 1.54% respectively. Conclusion: the prevalence of hepatitis B is considerable and confirms that our country belongs to the area of high endemicity of hepatitis B virus infection.