TITLE:
Seroprevalence of Human Immunodeficiency Virus and Hepatitis B in Blood Donors at the N’Zérékoré Regional Blood Transfusion Centre in Guinea
AUTHORS:
Alimou Camara, Ernest Thea, Ives Nyankoye Haba, Yamoussa Youla, Ibrahima Sory Diallo, Mariama Sadio Diallo, Djiba Kaba, Jacob Camara, Moussa Condé, Barré Soropogui, Kaba Kourouma, Thierno Mamadou Tounkara, Babacar Mbengue, Abdoulaye Touré, Sanaba Boumbaly
KEYWORDS:
Seroprevalence, HIV, Hepatitis B, Blood Donors, N’Zérékoré, Guinea
JOURNAL NAME:
Open Journal of Immunology,
Vol.14 No.2,
June
28,
2024
ABSTRACT: Blood transfusion saves lives and reduces morbidity and mortality for a large number of diseases and clinical conditions, but it is not without danger. The aim of this study was to determine the seroprevalence of HIV and hepatitis B in blood donors received at the regional Blood Transfusion Centre of N’Zérékoré (Guinea). This was a 5-year retrospective analytical study. We included records of blood donors aged 18 to 60 years admitted to the N’Zérékoré Regional Blood Transfusion Centre for blood donation from January 2016 to December 2020. We performed a descriptive analysis followed by Chi-2 or Fish-er-exact tests and the Student or Wilcoxon test, followed by multivariate logistic regression. In this study, donor age ranged from 18 - 60 years, with a pre-dominance of donors aged 25 - 34 (44.2%). Male donors were the most represented in our study (79.0% versus 21.0% female). More than half of the donors were blood group O (55.6%). We observed a seroprevalence of 3.6% for HIV, 13.4% for HBsAg and 0.2% for co-infection. In our series, age 25 - 34 (OR = 1.89 and P = 0.001) and 35 - 44 for HIV (OR = 2.01 and P = 0.001), HBsAgserostatus (OR = 3.04 and P = 0.001) and blood donation history (OR of 3.04 and P = 0.001) were factors associated with HIV positivity (P