Wasserman, R.L., Irani, A.M., Tracy, J., Tsoukas, C., Stark, D., Levy, R., Chen, J., Sorrells, S., Roberts, R. and Gupta, S. (2010) Pharmacokinetics and safety of subcutaneous immune globulin (human), 10% caprylate/ chromatography purified in patients with primary immunodeficiency disease. Clinical & Experimental Immunology, 161, 518-526. doi10.1111/j.1365-2249.2010.04195.x - References

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Wasserman, R.L., Irani, A.M., Tracy, J., Tsoukas, C., Stark, D., Levy, R., Chen, J., Sorrells, S., Roberts, R. and Gupta, S. (2010) Pharmacokinetics and safety of subcutaneous immune globulin (human), 10% caprylate/ chromatography purified in patients with primary immunodeficiency disease. Clinical & Experimental Immunology, 161, 518-526. doi:10.1111/j.1365-2249.2010.04195.x

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JOURNAL NAME: Open Journal of Immunology, Vol.1 No.3, December 31, 2011

ABSTRACT: Several groups are investigating the mechanisms of action of therapeutic immunoglobulins (IVIg) in order to improve their use. In vitro models such as CD40-CD154 interaction are necessary to study the physiological response of human B lymphocytes to IVIg. Human B lymphocytes treated with IVIg triggers a rapid phospho-rylation (

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